Anne Vassalli
@annevassalli.bsky.social
Sleep and hypothalamic control of brain states & cell fates | Arousal disorders incl Narcolepsy, ADHD, OCD 🔶@Innosuisse "Proof-of-concept of narcolepsy reversal by epigenetic therapy" https://wp.unil.ch/vassallilab/ Migrated from https://x.com/AnneVassalli
Excited to share our freshly published @nature.com Reviews Neurology Perspective ⭐️ 💎 #Narcolepsy may not just be the irreversible autoimmune killing of #hypocretin/orexin neurons but amenable to their functional restoration. rdcu.be/fpFes @fbm-unil.bsky.social #ali.seifinejad
Excited to share our new preprint! www.biorxiv.org/content/10.1... Divergent modulation of dopaminergic neurons by hypocretin/orexin receptors-1 and -2 shapes dopaminergic cell activity and socio-emotional behavior Tzanoulinou et al Supported by @snsf.ch
Join us in Lausanne 🇨🇭 for the Lac Léman Regenerative Medicine Symposium, Sept 17–19, 2025! 🔬 Stem cells, aging, bioengineering — shaping the future of regenerative medicine. habiblab.org/l2rm 🎟️ Students 25 CHF | Postdocs/Faculty 50 CHF | Industry 150 CHF #L2RM #RegenMed #StemCells
Our follow-up study on the orexin↔dopamine neuronal interplay is here to share! We discover opposite action of #hypocretin/orexin A vs B via #OX1R vs #OX2R on VTADA cell excitability +demonstrate striking distinct impact of DA cell Ox1 vs 2R loss on mouse behavior in socioemotional&cognitive domain
Divergent modulation of dopaminergic neurons by hypocretin/orexin receptors-1 and -2 shapes dopaminergic cell activity and socio-emotional behavior
Many neuropsychiatric disorders involve dysregulation of the dopaminergic (DA) input to the forebrain. Of particular relevance are DA projections originating from the midbrain ventral tegmental area (...
biorxiv.org