Arnaud Le Rouzic

@arnaudlerouzic.bsky.social

CNRS researcher (IDEEV, Université Paris-Saclay, France). Evolutionary genetics, theoretical quantitative genetics, systems biology. Associate editor at J. Evol. Biol. Bridge to my Mastodon account: @arnaudlerouzic.fediscience.org.ap.brid.gy

Do we really understand how complex systems evolve? Based on experimental evolution in stable vs fluctuating temperature conditions, we show that adaptive mutations in the fungus Zymoseptoria tritici are (i) massively pleiotropic, and (ii) opposed to the phenotypic plasticity.

Graphical summary of the experimental evolution protocol. Strains of the fungus Zymoseptoria tritici were raised in stable cool, stable warm, or fluctuating temperature conditions for ~ 250 generations, with 2 initial genotypes are three evolutionary replicates. The transcriptome was sequenced before and after evolution at both temperatures. Illustration of the unexpected response of gene expression plasticity to the evolutionary treatment. Plasticity (i.e. the difference in expression between 23°C and 17°C) evolved more in stable conditions than in fluctuating conditions. Contergradient plasticity: gene expression in stable conditions evolved in a direction opposite to the initial plasticity, as if plasticity in the initial strains was maladaptive.
bioRxiv Evolutionary Biology@biorxiv-evobio.bsky.social · 9mo ago

Adaptive evolution of transcriptome and transcriptomic plasticity in stable and fluctuating environments https://www.biorxiv.org/content/10.64898/2026.02.16.706080v1

We were all very sad to learn the death of Pierre Capy. Pierre was a professor at University Paris Saclay, in the 1990s, he started a group working on the evolutionary genomics of transposable elements; this group is still very active today. He was a great teacher, mentor, and colleague.

@ideevl.bsky.social · 9mo ago

Pierre Capy était un généticien, un drosophiliste, un acteur majeur dans l'essor de la génétique des éléments transposables en France. Très impliqué dans l'administration de la vie scientifique, il a aussi été directeur du laboratoire LEGS (actuel @EGCE), et un des fondateurs en 2016 de @IDEEV.

Very proud to see this work highlighted by the journal! Publishing in Evolution has always meant something special to me. Congrats to the first author Sylvain Pouzet who found the energy to keep on working on his master project during his PhD.

Evolution@journal-evo.bsky.social · last yr.

Don't miss this issue's Editor's Choice article: "Gene network topology drives the mutational landscape of gene expression" by Sylvain Pouzet & Arnaud Le Rouzic. Free to read here: doi.org/10.1093/evol...

SpringerNature keeps on creating new outlet after new outlet... Seems like nothing can stop them. Just like that joke of a guy putting coins into the soda vending machine: "So long as I'm winning, I'm playing"... But who pays? We researchers are the fools and we seem to like it.

Nature Portfolio@natureportfolio.nature.com · 2y ago

Introducing Nature Reviews Biodiversity! This Review explores the relationship between emerging infectious diseases and biodiversity loss, and how both are connected to global environmental changes in the Anthropocene. https://go.nature.com/42fzUQk 🧪

This is figure 2, which shows two perspectives on land use as a driver of biodiversity loss and disease emergence.