Arnone Lab

@arnonelab.bsky.social

Group established in 2000, studying echinoderms to unravel the evolution of organs and body parts by comparison of gene regulatory networks. https://arnonelab.it/

These images show live embryos of animals (jellyfish, crustacean, worm, sea urchin, sea squirt, beetle) and one of animals closest single-celled relatives. They were captured taking advantage of fluorescent proteins localised on the outer membrane of cells, allowing us to observe cell outlines. 1/9

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Finding molecular tags that localise fluorescent proteins to the cell membrane was the goal of our latest paper, now published in Development @dev-journal.bsky.social. The tags act as address labels, sending proteins to the cell membrane, where they highlight the shape and arrangement of cells. 2/9

Targeting the cell membrane in established and emerging model organisms

Summary: Screening a toolkit of diverse membrane-localising tags identifies candidates that efficiently localise proteins to the plasma membrane in a wide range of animals and choanoflagellates.

journals.biologists.com

We are excited to share that we are hosting a hands-on course on "Electron Microscopy of Marine Environmental Samples" 🔬🌊 📍Naples, Italy 🗓️ 8th-11th of April 2026 If you are interested, check the program below! Registration is open until the 12th of February. We look forward to seeing you there!

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I am deeply honored to share that my project NeurEvoFun has been awarded support from the Fondo Italiano per la Scienza (FIS), the Advanced Grant by the Italian Ministry of Education, Universities and Research, supporting fundamental research inspired by the ERC model. Excited for what’s ahead!

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Our study, just published in #ScienceAdvances and funded by @hfspo.bsky.social, explores the post metamorphic cell composition of the sea urchin juvenile, revealing that its body is head-like. Long considered brainless creatures, they’re all brain instead! www.science.org/doi/10.1126/...

Single-nucleus profiling highlights the all-brain echinoderm nervous system

A sea urchin is a head with a brain-like organization and a vertebrate-type retinal signature.

science.org