The paper from my postdoc days @mblscience.bsky.social and @zakswartz.bsky.social Lab is available in @natcomms.nature.com. www.nature.com/articles/s41... With Beverly Naigles, @carsten-wolff.bsky.social and @danivoronov.bsky.social
Arnone Lab
@arnonelab.bsky.social
Group established in 2000, studying echinoderms to unravel the evolution of organs and body parts by comparison of gene regulatory networks. https://arnonelab.it/
Fantastic seminar by Chris @lowelab.bsky.social. It’s been a real pleasure having you at @szndohrn.bsky.social these days. With @arnonelab.bsky.social
🔬 Meet Ina Arnone, ZooCELL PI at @szndohrn.bsky.social In this Q&A, she shares how she discovered EvoDevo, the big questions driving their research and her passion for mentoring the next generation of scientists. Follow the thread to learn more. 👇 #MSCA #ZooCELL #EvoDevo @arnonelab.bsky.social
(1/2) What a fantastic week for the Arnone Lab at #EED2026 in Glasgow! Our lab’s work was showcased through contributed talks by @perievodevo.bsky.social in S19 and @mlrusciano.bsky.social in S02, as well as an invited talk by Ina in S15.
At @szndohrn.bsky.social, the floor tiles have stitching and segmentation artifacts :) Just finished teaching the marvels of spatial omics to the great group of PhD students of @zoocell.biologists.social.ap.brid.gy, together with @alvarocrevenna.bsky.social. What a week! 🔬🍕🍝🍷🧪
Thrilled to present our comparative study on the evolution of zygotic genome activation (ZGA)!! 🥚🧬 Amazing PhD work of @campobes.bsky.social together with @fedemantica.bsky.social and many collaborators! @melisupf.bsky.social @crg.eu. Thread below 1/15 www.biorxiv.org/content/10.6...
biorxiv.org
These images show live embryos of animals (jellyfish, crustacean, worm, sea urchin, sea squirt, beetle) and one of animals closest single-celled relatives. They were captured taking advantage of fluorescent proteins localised on the outer membrane of cells, allowing us to observe cell outlines. 1/9
Finding molecular tags that localise fluorescent proteins to the cell membrane was the goal of our latest paper, now published in Development @dev-journal.bsky.social. The tags act as address labels, sending proteins to the cell membrane, where they highlight the shape and arrangement of cells. 2/9
Targeting the cell membrane in established and emerging model organisms
Summary: Screening a toolkit of diverse membrane-localising tags identifies candidates that efficiently localise proteins to the plasma membrane in a wide range of animals and choanoflagellates.
journals.biologists.com
There are just a few days (and spots!) left to apply to this EM course with a focus on marine samples 🌊 do not miss it!
Don’t forget to apply to this beautiful Electron Microscopy course at @szndohrn.bsky.social in Napoli, Italy by February 12th! 🌊 ☀️ Stay tuned for the preliminary program, in the meantime take a look here: www.szn.it/index.php/it...
We are excited to share that we are hosting a hands-on course on "Electron Microscopy of Marine Environmental Samples" 🔬🌊 📍Naples, Italy 🗓️ 8th-11th of April 2026 If you are interested, check the program below! Registration is open until the 12th of February. We look forward to seeing you there!
New findings on genomic regulation mechanisms throughout evolution | EurekAlert! www.eurekalert.org/news-release...
New findings on genomic regulation mechanisms throughout evolution
The conservation of genome regulatory elements over long periods of evolution is not limited to vertebrates, as previously thought, but also in echinoderms (invertebrates). This is one of the most not...
eurekalert.org
EMHOC’s preliminary program is out. Check it out to stay updated!
EMHOC 2026 preliminary program
EMHOC 2026 Preliminary Program Day 1 - Wednesday, April 8th 13h00 - 14h00 Arrival and registration 14h00 - 14h15 Welcome and introduction to the course Giovanna Benvenuto, Stazione Zoologica Napoli, ...
docs.google.com
Our work on the evolution of the regulatory genome of echinoderms is now out in @natecoevo.nature.com. Led by my former PhD Marta Magri, Danila Voronov & Saoirse Foley. Great collaboration of Arnone, Hinman & Maeso labs, started long time ago with our missed José Luis Gomez-Skarmeta: rdcu.be/eXX8l
Deep conservation of cis-regulatory elements and chromatin organization in echinoderms uncover ancestral regulatory features of animal genomes
Nature Ecology & Evolution - Analysis of the 3D chromatin architecture and cis-regulatory elements in a sea urchin and a sea star reveals mechanisms of 3D chromatin organization in echinoderms...
rdcu.be
I am extremely proud and happy to announce that another paper from my PhD days has just been published in @natecoevo.nature.com on evolution of genome and gene regulation thanks to all the amazing people involved. Check the paper out at: www.nature.com/articles/s41...
Deep conservation of cis-regulatory elements and chromatin organization in echinoderms uncover ancestral regulatory features of animal genomes - Nature Ecology & Evolution
Analysis of the 3D chromatin architecture and cis-regulatory elements in a sea urchin and a sea star reveals mechanisms of 3D chromatin organization in echinoderms and the long-term evolutionary dynam...
nature.com
Exciting news to start the new year! We’re thrilled to see this work finally out in @natecoevo.nature.com, the result of a major collaboration between my lab and the labs of Veronica Hinman and Nacho Maeso, began many years ago with the dear José Luis Gómez-Skarmeta. www.nature.com/articles/s41...
Don’t forget to apply to this beautiful Electron Microscopy course at @szndohrn.bsky.social in Napoli, Italy by February 12th! 🌊 ☀️ Stay tuned for the preliminary program, in the meantime take a look here: www.szn.it/index.php/it...
I am deeply honored to share that my project NeurEvoFun has been awarded support from the Fondo Italiano per la Scienza (FIS), the Advanced Grant by the Italian Ministry of Education, Universities and Research, supporting fundamental research inspired by the ERC model. Excited for what’s ahead!
Beautiful course on electron microscopy coming soon in Naples, do not miss it!
The "Electron Microscopy Hands-On Course" returns for its 2nd edition in April 8-11, 2026, at the Stazione Zoologica Anton Dohrn in Naples, Italy. Explore the course overview and start your application here: www.szn.it/index.php/it...
What a nice way to end the year - last shift of 2025 on the EMBL beamline P14 on Petra III in Hamburg! With @mlrusciano.bsky.social we did x-ray imaging of sea urchin larvae and had the honor of using the synchrotron ourselves! Many thanks to Angelika Svetlove. @embl.org
In preprints: cell type-specific gene regulation through the lens of echinoderms Periklis Paganos and @arnonelab.bsky.social discuss a recent #preprint by Jonas Maurice Brandenburg, David Aaron Garfield and colleagues doi.org/10.1242/dev....
Our study, just published in #ScienceAdvances and funded by @hfspo.bsky.social, explores the post metamorphic cell composition of the sea urchin juvenile, revealing that its body is head-like. Long considered brainless creatures, they’re all brain instead! www.science.org/doi/10.1126/...
Single-nucleus profiling highlights the all-brain echinoderm nervous system
A sea urchin is a head with a brain-like organization and a vertebrate-type retinal signature.
science.org
We discuss new research on sea urchins, how echinoderms remain relevant experimental systems in the multiomics era, and the future of the cell type evolution and development field.
Thrilled to share my newest perspective article with @arnonelab.bsky.social in @dev-journal.bsky.social journals.biologists.com/dev/article/...
In preprints: cell type-specific gene regulation through the lens of echinoderms
One of the most intriguing questions in developmental biology is how a single cell, the zygote, gives rise to hundreds or millions of distinct cell types during embryogenesis. Decades of research have...
journals.biologists.com
We‘re thrilled to be involved in this great open science initiative; @mlrusciano.bsky.social really enjoyed testing this tool in sea urchins!
How can we see the cells that make up a living organism? Membrane-localising tags can drive fluorescent proteins to the cell's outer membrane, making their outlines visible. But the tags don't work well in all organisms. How do you find one for your species of interest? 🧵 Check our latest preprint
Very proud to be a part of this!
Happy to share the Biodiversity Cell Atlas white paper, out today in @nature.com. We look at the possibilities, challenges, and potential impacts of molecularly mapping cells across the tree of life. www.nature.com/articles/s41...
Do you want to unravel the function of fluorescent cells in marine organisms? Join the Annunziata lab @szn.it for a PhD project exploring embryonic origins, function and biotechnological potential of fluorescent cell type in sea cucumbers! To apply: www.szn.it/.../ph-d-pro...
Do you want to understand how developmental programs are encoded in animal genomes? Join our lab at the @szndohrn.bsky.social for a PhD project to unravel the developmental dynamics in sea urchins during the metamorphosis from larva to juvenile. Deadline JUNE 14th! www.szn.it/index.php/it...
It's only mid-April, but course season at the MBL is already underway! 🔬 Gene Regulatory Networks for Development started on April 6 and wraps up later this week 🧬 Congrats to this year's cohort! 👏 📲 Read more about the GRN course: bit.ly/3Wi6LQE