Cyberattacks have halted care and disrupted devices across U.S. clinics. In a new piece, @arpa-h.bsky.social explains why it’s funding real-world cyber protections. Proud our CHC team built CRASHCART, restoring critical systems fast when ransomware hits. Read⬇️ arpa-h.gov/news-and-eve...

Modern Cyber Defenses: Resilient networks mean healthier patients and uninterrupted care

The Advanced Research Projects Agency for Health (ARPA-H) supports transformative research to drive biomedical and health breakthroughs ranging from molecular to societal to provide transformative hea...

arpa-h.gov

Osteoarthritis is the 3rd most common disease in the U.S. With funding from @arpa-h.bsky.social, researchers at CU Boulder, @cuanschutz.bsky.social and CSU developed therapies that help damaged joints repair themselves within weeks (animal studies). More via @nytimes.com ↓ https://nyti.ms/4c7hgxl

Federal Agency Unveils Three Potential Osteoarthritis Treatments

With funding from ARPA-H, three teams of researchers have regrown bone and cartilage, even entire knees, in animal studies. Human trials are not far off.

nyti.ms

Review of biosensing technologies for detecting airborne pathogens, led by Rajan Chakrabarty with small contributions from me. www.sciencedirect.com/science/arti... funded by @arpa-h.bsky.social

Airborne pathogen detection using electrochemical biosensors: Research status and future directions

Airborne pathogens pose a significant public health challenge. The ability to detect them efficiently and provide actionable data to mitigate risk in …

sciencedirect.com

Our friends at @arpa-h.bsky.social are looking for multidisciplinary teams for HEARING (Hearing Enhancement through Artificially Intelligent Neurotechnology), a new program focused on developing the first brain-driven, minimally invasive hearing system. arpa-h.gov/news-and-eve... #keeplistening

ARPA-H launches program to restore natural hearing through first brain-driven hearing system

The Advanced Research Projects Agency for Health (ARPA-H) supports transformative research ranging in scale from molecular to societal to deliver health breakthroughs in years, not decades.

arpa-h.gov

What if cancer treatment took days — not months? 1-CURE is pursuing a single, fast, low-cost radiotherapy effective across ALL cancers — even metastatic and treatment-resistant tumors. Register for hybrid Proposers' Day on 3/24 in Houston, TX. arpa-h.gov/explore-fund...

A child’s chance of surviving cancer shouldn’t depend on their ZIP code. PCX is building secure, AI-powered data sharing across 200+ pediatric centers — designed with family and clinician input from day one. arpa-h.gov/news-and-eve...

Pediatric Care eXpansion (PCX): It takes a community to save a child

The Advanced Research Projects Agency for Health (ARPA-H) supports transformative research to drive biomedical and health breakthroughs ranging from molecular to societal to provide transformative hea...

arpa-h.gov

Children with life-threatening rare diseases can’t wait for better data. UNICORN is building a predictive model to determine which cell therapy designs deliver the safest, most durable cures — unlocking progress for ~600 rare pediatric diseases. arpa-h.gov/explore-fund...

UNICORN: UNIfying Cell Therapy Outcome prediction and Regulatory Navigation

The Advanced Research Projects Agency for Health (ARPA-H) supports transformative research to drive biomedical and health breakthroughs ranging from molecular to societal to provide transformative hea...

arpa-h.gov

The body doesn’t send push notifications. It should. ARPA-H's new Delphi program was built to empower people to know themselves in a way never before possible. Learn more and register for hybrid Proposers’ Day on March 27 in Tempe, AZ: www.arpa-h.gov/news-and-eve...

On #WorldLymphedemaDay, we’re standing with the lymphedema community to confront a system medicine has overlooked for too long. For decades, the lymphatic system has been understudied. Under-imaged. Underestimated. (1/3)

Boston, you reminded us why this work matters. The minds, the mission, the momentum — thank you for opening your doors for our visit.

Creating more “Happy Birthday”s & “Happy Anniversary”s. By monitoring the immune system during critical care, our CIRCLE program will empower doctors to fine-tune treatments, halt disease progression & save lives. Register for Proposers' Day in Arlington, VA on 3/11. www.arpa-h.gov/explore-fund...

There's a reason Boston is a global hub for health innovation. Thank you for having us for a second jam-packed day — the energy here is unmatched and we're just getting started.

For decades, medicine managed chronic disease symptoms — while ignoring the system connecting them all. When it breaks down, the damage radiates everywhere — heart failure, diabetes, autoimmune disease, obesity. And there are zero FDA-approved treatments that actually repair it. (1/2)

We’re LIVE in Boston and surrounded by innovators who refuse to accept the status quo in health. Boston is where biotech's brightest minds push boundaries and save lives. That's exactly why we're doubling down here ensuring every dollar drives game changing breakthroughs. (1/2)

What if the ultimate health monitor was invisible? OCULAB teams are building sensors that live in your tear duct, read your body's chemistry in real time, and deliver treatment when you need it — not on a fixed schedule. arpa-h.gov/news-and-eve...

Day 1: Boston doesn't just talk about the future — it builds it. Grateful to be in a city that matches our urgency.

50% of childhood cancers are rare. Pediatric Care eXpansion is building a network so every kid can access care—no matter their zip code. These are the voices moving us — and our partners — forward. #RareDiseaseDay www.youtube.com/playlist?lis...

PCX ~ Creating Change for Pediatric Care in Rare Disease - YouTube

50% of childhood cancers are rare. ARPA-H's Pediatric Care eXpansion (PCX) is building a network so every kid can access care—no matter their zip code. These...

youtube.com

Your proteins are making deadly typos. BIOGAMI is teaching them to spell correctly. When proteins in the body misfold, they can trigger diseases like ALS, Parkinson's and Alzheimer's – but what if we intervene before that happens? Watch Proposers' Day highlights ⬇️ arpa-h.gov/explore-fund...

Last week's PCX Roadshow proved something powerful: when you put the right mission in front of the right people, momentum builds fast. 200+ pediatric hospitals & care centers. One network. This is what happens when dedication meets urgency. Learn more: arpa-h.gov/news-and-eve...

Most of us don’t just want longer lives, but more years of good health. PROSPR awardees are spotting early signs that health is slipping, building systems for aging clinical trials & testing new drugs that could be the 1st gen drugs to extend healthy years. Meet the teams: arpa-h.gov/news-and-eve...

200+ hospitals. One mission: ending pediatric brain cancer. Our Pediatric Care eXpansion (PCX) effort launched with $50M to ensure every child and their families have access to the best possible care, regardless of where they live. (1/2)

Critical illness moves fast. We need to track its every move. CIRCLE is making that possible — using AI + digital twin technology to control the body’s immune response in real time, so clinicians can personalize care when every second counts. Learn more: arpa-h.gov/news-and-eve...

Cancer changes. Your treatment should too. Too many of our loved ones have been treated with a plan made on Day 1, even when their tumor evolves, resists, and outsmarts that plan by month three. ADAPT trials will track tumors in real-time — (1/2)

World-class care, no matter where you live. Every town, every county, every zip code. This week, ARPA-H collaborated with HHS Deputy Secretary Jim O’Neill and CMS Administrator Dr. Mehmet Oz to do something big... (1/2)

🚨 BIOGAMI Proposers' Day Registration is closing soon – sign up by Feb. 18 at 5pm ET for in-person attendance, or by Feb. 19 at noon ET for virtual attendance. arpa-h.gov/explore-fund...

ARPA-H@arpa-h.bsky.social · 7mo ago

What if we could detect & repair the earliest stages of protein dysfunction in the body to eliminate diseases like ALS & Parkinson's? Our BIOGAMI program will crack the code on disordered proteins—and then harness that knowledge to force misfolded proteins back into line. arpa-h.gov/news-and-eve...

PROSPR (Proactive Solutions for Prolonging Resilience) is tackling humanity's most ambitious challenge: stopping age-related diseases before they start, extending years of vitality. ARPA-H Program Manager Dr. Andrew Brack spoke to TIME about "The Age of Longevity" ⬇️ time.com/collections/...

The Race to Measure How We Age

As biological age tests proliferate, experts are excited about their potential—but warn of their limits.

time.com

Big healthcare breakthroughs rarely happen in silos. Our programs are built for multidisciplinary teams — bringing together builders across the biomedical ecosystem to turn ambitious ideas into real-world solutions. Learn how to assemble the ultimate team 👇 arpa-h.gov/news-and-eve...

ARPA-H 101: Assembling a research team

The Advanced Research Projects Agency for Health (ARPA-H) supports transformative research to drive biomedical and health breakthroughs ranging from molecular to societal to provide transformative hea...

arpa-h.gov

Clinical need is constant. Supply chains aren’t. We can’t keep relying on slow and outdated paths to produce the active ingredients our medicines depend on. WHEAT is building a simpler, scalable way to produce APIs — using American-grown wheat and wheat germ extract. (1/3)

Freezers shouldn’t decide who gets life-changing therapies. BoSS is pushing past cold-chain limits to develop room-temperature stable biologics — unlocking access for patients in every community. Catch the Proposers’ Day highlights! arpa-h.gov/explore-fund...