Tomoko Miyakubo et al. from Teikyo University investigate morphological changes in fungal elements and antifungal drug susceptibility in an Ex Vivo model of fungal keratitis. doi.org/10.1167/iovs.67.10.13
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Rafael André da Silva et al. from UNESP, São José do Rio Preto nvestigate the role of the AnxA1 protein in diabetic retinopathy (DR) and to understand how its absence affects inflammation and vascular dysfunction in DR. doi.org/10.1167/iovs.67.10.12
Yasuo Yanagi et al. from Singapore Eye Research Institute find that caveola and Its resident proteins, caveolin-1 and -2, play critical roles in the pathogenesis of nAMD and PCV. doi.org/10.1167/iovs.67.10.10
Jinling Fu et al. from the Second Hospital of Jilin University find that WDR34 deficiency disrupts retrograde intraflagellar transport and induces unfolded protein response-driven inflammation and retinal degeneration. doi.org/10.1167/iovs.67.10.9
Sayan Basu et al. from the L. V. Prasad Eye Institute investigate the association of IL-8 and IL-18 expression with histone-associated NETosis in aqueous-deficient and evaporative dry eye disease. doi.org/10.1167/iovs.67.10.8
Divya Rodrigues et al. from Macquarie Medical School investigate the impact of continuous positive airway pressure treatment on retinal vasculature in obstructive sleep apnea. doi.org/10.1167/iovs.67.10.7
Ruibo Yang et al. from Tianjin Medical University Eye Hospital investigate the role of Z‑nucleic acids (Z‑NAs) in the pathogenesis of fungal keratitis (FK), focusing on its regulatory effects on fungal immune escape, inflammation, and biofilm activity. doi.org/10.1167/iovs.67.10.6
Ryo Kawasaki et al. from the University of Osaka estimate the distribution and temporal trends of refractive errors among spectacle wearers in Japan using a nationwide database of optical chain stores. doi.org/10.1167/iovs.67.10.5
Lisa A. Ostrin et al. from the University of Houston quantify ocular parameters and their relationships during normal ocular development in rhesus monkeys. doi.org/10.1167/iovs.67.10.4
Bo Wu et al. from Sichuan University investigate whether retinal and choroidal microvascular and neurostructural measures reflect cerebral atrophy and cognitive impairment in noninfarcted large artery stenosis. doi.org/10.1167/iovs.67.10.3
Susanne Roosing et al. from Radboud University Medical Center Identify a duplication in the RP17 locus in an individual with pathogenic CEP290 variants. doi.org/10.1167/iovs.67.10.1
Douglas Borchman et al. study the Direct Correlation of Levels of Meibum Cholesteryl Esters, Hydrocarbon Chain Saturation, and Protein With Lipid Structure, in Relation to Age and Dry Eye, iovs.arvojournals.org/article.aspx....
Srinivas Sadda et al. investigate the Quantitative Evaluation of Geographic Atrophy Progression Using Geographic Atrophy Lesion Front Displacement, iovs.arvojournals.org/article.aspx....
Wei Chen et al. find that Topical Glycolysis Inhibition Restores MAVS-Associated Antiviral Signaling in Herpes Simplex Keratitis, iovs.arvojournals.org/article.aspx....
New in the Nystagmus issue bit.ly/499ScFg, Fatema Ghasia et al. report that Amblyopia Severity Predicts Fixation Dysfunction Independent of Nystagmus and Foveation Disruption in Fusion Maldevelopment Nystagmus, iovs.arvojournals.org/article.aspx....
Jiawei Zhou et al. report their work on A Shared Genetic Basis Underlying Myopia–Exotropia Comorbidity, iovs.arvojournals.org/article.aspx....
Yadi Chen and Paul Donaldson report that Extrinsic Modulation of the Zonular Tension Induces Calcium Influx in Lens Fiber Cells That Is Mediated by Mechanosensitive TRPV1 and TRPV4 Channels, iovs.arvojournals.org/article.aspx....
Dimitra Skondra et al. investigate the Association of Antibiotic Use and New-Onset ICD Coding of Geographic Atrophy, iovs.arvojournals.org/article.aspx....
C. Gustavo De Moraes et al. present A Topographical Analysis of Visual Field Improvement in a Phase 2 Randomized Trial of Nicotinamide and Pyruvate for Open-Angle Glaucoma, iovs.arvojournals.org/article.aspx....
Kyosuke Satake et al. assess Preclinical Ocular Pharmacokinetics and Efficacy of Novel Tivozanib Eye Drops for Neovascular Age-Related Macular Degeneration, iovs.arvojournals.org/article.aspx....
Haotian Lin et al. share their work on Anteroplacement of the Mucocutaneous Junction and Goblet Cell Expansion: Microanatomic Remodeling of the Human Eyelid Margin, iovs.arvojournals.org/article.aspx....
Zhaohui Li et al. find that CD14+CD56+ Cell Is an Independent Regulatory Monocyte Subpopulation Increased in VKHS Patients Following Glucocorticoids Therapy, iovs.arvojournals.org/article.aspx....
Syed Adeel H. Zaidi et al. report on the Novel Role of AcylCoA: Cholesterol Acyltransferase 1/Sterol O-Acyltransferase 1 (ACAT1/SOAT1) in Diabetic Retinopathy, iovs.arvojournals.org/article.aspx....
Hiroki Mieno et al. study Compartment-Specific Associations of GDF15 With Intraocular Cytokines in Patients With Idiopathic Epiretinal Membrane, iovs.arvojournals.org/article.aspx....
Anna Maria Welzel et al. present their work on Anisometropia and Its Related Traits: Ocular, Systemic, and Genetic Characteristics—Results From the Gutenberg Health Study, iovs.arvojournals.org/article.aspx....
Jianbo Mao et al. share their work on Optic Nerve Alterations Following Intravitreal Injection and Laser in Infants With Retinopathy of Prematurity, iovs.arvojournals.org/article.aspx....
SriniVas Sadda et al. share their work on Incomplete Retinal Pigment Epithelium and Outer Retinal Atrophy Characterized Using Fundus Autofluorescence: An 18-Month Post Hoc Analysis of GATHER2, iovs.arvojournals.org/article.aspx....
Xiangrong Kong et al. report on Lens Opacity in ABCA4-Associated Stargardt Disease Patients in the ProgStar Study, iovs.arvojournals.org/article.aspx.... From Natural History to Clinical Trials in IRDs: Insights into Pathogenesis, Progression, and Outcome Measures, bit.ly/4yyWsJp
Zhixiang Ding et al. report that LAG3 Gene Therapy Attenuates Autoimmune Uveitis by Regulating the PI3K/Akt Signaling Pathway, iovs.arvojournals.org/article.aspx....
Hong Wang et al. report that VISTA Deficiency Exacerbates Autoimmune Uveitis by Promoting Microglial Activation via the TLR4/MyD88/NF-κB Pathway, iovs.arvojournals.org/article.aspx....