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Austrian Society of Plant Biology

@atspb.bsky.social

10 Posts229 Follower416 Folgt
Austrian Society of Plant Biology@atspb.bsky.social · 4mo ago

Save the date @atspb.bsky.social @wolframweckwerth.bsky.social are looking forward to hosting you 17-20.August 2027 in Vienna Plant Biology Europe Congress and please share the information

Austrian Society of Plant Biology@atspb.bsky.social · 5mo ago

Stay tuned… the Austrian Society of Plant Biology  will host the next Federation of European Societies of Plant Biology conference in Vienna, 17-20 August 2027 save the date and we will soon upload new details #fespb #plantscience #societiesofplantbiology

Kati Retzer @katarzynaretzer.bsky.social · 11mo ago

The ability of roots to control their growth direction will never stop to amaze me 😀 #gravitropism #roots #barley #rootphenotyping monitoring dynamics of root growth changes on soil (frames every 10 min during 1h, 1DAG primary root, 2nd time gravistimulated in a row)

Kati Retzer @katarzynaretzer.bsky.social · 11mo ago

#roots #rootphenotyping on soil 🔬 DIY setup to track dynamic root growth continously without disturbing root using IRLEDs #plantscience @raspberrypi.com @openflexure.bsky.social @bokuvienna.bsky.social #simonpree @katarzynaretzer.bsky.social @barleymicrobreed.bsky.social

@wolframweckwerth.bsky.social · last yr.

CONGRATULATIONS: New publication by Wan Li from #WeckwerthLab: Hesperitin, a natural product from citrus fruits, protects against non-alcoholic fatty liver disease (NAFLD), a major cause for metabolic syndrome, diabetes and cardiovascular diseases. pubs.acs.org/doi/10.1021/...

Hesperetin Protects from Palmitic-Acid-Induced Lipotoxicity through the Inhibition of Glutaminolysis, mTORC1 Signaling, and Limited Apoptosis

Palmitic acid-induced lipotoxicity contributes to the development of nonalcoholic fatty liver disease (NAFLD). Hesperetin has been reported to alleviate oxidative stress, inflammation, and cell death in NAFLD, while its potential to mitigate palmitic acid-induced lipotoxicity remains unexplored. This study investigates the protective effects of hesperetin on palmitic-acid-stimulated lipotoxicity and elucidates the underlying molecular mechanisms. Our results showed that hesperetin decreased palmitic acid-activated lipotoxicity through inhibition of the intrinsic apoptosis pathway and promotion of autophagic flux. Metabolomics analysis and stable-isotope-tracing data indicated that hesperetin treatment restored the aberrant tricarboxylic acid cycle caused by palmitic acid exposure, accompanied by a decrease in anaplerotic flux from glutamine to α-ketoglutarate. The reduction of α-ketoglutarate resulted in the inhibition of mTORC1 signaling, which in turn activated autophagy and limited apoptosis. Furthermore, hesperetin activated AMPK, which coordinated with mTORC1 to regulate autophagy. Additionally, hesperetin reinstated the activation of AKT and Nrf2, further protecting the cell against the deleterious effects of lipotoxicity. These data highlight the role of glutaminolysis as a survival mechanism for preventing lipotoxicity upon hesperetin treatment.

pubs.acs.org

Universität Wien / University of Vienna@univie.ac.at · last yr.

Holobiont-Revolution: Wie Weizen durch naturbasierte Pflanzenzüchtung & #MachineLearning klimaresilienter wird🌡️ Stickstoffdünger in der Landwirtschaft trägt erheblich zur Klimaerwärmung bei. Ein neues Züchtungskonzept, speziell für Weizen, könnte eine Verringerung der Stickstoffdüngung ermöglichen ⤵️

Die Holobiont-Revolution: Wie Weizen durch naturbasierte Pflanzenzüchtung und Machine Learning klimaresilienter wird

Wechselwirkung von Mikrobiom und Pflanze im Fokus

medienportal.univie.ac.at