Our paper "Active-learning-guided optimization of cell-free systems for genome-wide transcriptomic profiling reveals progressive layers of regulation" is online in Nature Communications! Congrats Lea Wagner, very proud of this work! www.nature.com/articles/s41... #cellfree #AI #T7Phage #synbio

Today in the lab we used protease inhibitors that are older than France’s first World Cup victory - and incidentally than many of my students. #oldbutgold #scienceisforever

PhD position in the Niederholtmeyer Lab (Straubing Germany) on feedback control of dynamic condensate assembly and disassembly edu.nl/7v364 Deadline: 26/04 @hniederho.bsky.social #SynCell #SyntheticCell

I’m very proud to share that I am a laureate of the Choose France for Science funding. This grant will help me build my lab over the next 3 years in France. Grateful to the @crpp-bordeaux.bsky.social, @cnrs.fr Chimie, @baretjc.bsky.social and others at the CRPP for their support.

This week we welcomed Aurore Dupin (@auroredupin.bsky.social) from CRPP Centre de Recherche Paul Pascal, hosted by Aitor Manteca (@manteka.bsky.social), for a fascinating seminar on surface-based cell-free platform to characterize host-pathogen interactions. #CICbiomaGUNEseminars #SyntheticBiology

I am very proud to share the core project of my post-doc in this beautiful paper. With colleagues at the Weizmann, we built biochips to interrogate antigen-antibody interactions at high-throughput and quantitatively. Check it out at @natnano.nature.com

DNA origami behaving like lipids. A very creative and exciting take from the Simmel Lab @simmellab.bsky.social on self-assembly of compartments. www.nature.com/articles/s41...

Self-assembled cell-scale containers made from DNA origami membranes - Nature Materials

Through the programmable self-assembly of lipid-inspired radially symmetric DNA, porous molecular membranes and cell-sized compartments are formed with applications in bottom-up biology and soft robot...

nature.com

A very cool paper from the Frey lab @physicsoflifelmu.bsky.social. Self-assembly governed by compartment geometry... Testing this in (surface-based) artificial cells would be exciting. Delay-facilitated self-assembly in compartmentalized systems | PNAS www.pnas.org/doi/10.1073/...

Delay-facilitated self-assembly in compartmentalized systems | PNAS

Self-assembly processes in biological and synthetic biomolecular systems are often governed by the spatial separation of biochemical processes. Whi...

pnas.org

Check this paper out: my colleague Ferdi Greiss trapped E.coli chromosomes in microfluidic reservoirs and looked at protein expression at the single molecule level.

Bacterial chromosome conformation and cell-free gene expression in synthetic 2D compartments

Nature Communications - Chromosomes are long DNA polymers, compacted in cells and fragile once released from the host. Here, authors report on a method to gently transplant bacterial chromosomes...

rdcu.be

It's a pleasure to formally be part of the lab. For many more years of good science & fun! An amazing place to be!🥳 Congrats also to @auroredupin.bsky.social for the CNRS position. So great to have you with us @crpp-bordeaux.bsky.social @univbordeaux.bsky.social www.crpp.cnrs.fr/nos-deux-rec...

Nos deux recrues 2025! - CRPP

Laura Alvarez Frances a été recrutée en juin 2025 en tant que Maitre de Conférence Université de Bordeaux. Elle était sur une chaire UB depuis quelques années et a obtenu sa titularisation ! Aurore Du...

crpp.cnrs.fr

Big news! I am starting my own research lab at the University of Bordeaux as a @cnrs.fr researcher. Excited to turn my dream job into a reality! I will join the @crpp-bordeaux.bsky.social and the fantastic team of @baretjc.bsky.social, Nicolas Martin and @lauraal.bsky.social. Check dupinlab.com.

Last Friday (June 27), with Christophe Danelon (INSA Toulouse), we organized in Bordeaux at @crpp-bordeaux.bsky.social the 1st meeting of SynCell Fr, gathering the French community tackling research activities on Synthetic Cells.

Beautiful study using artificial/living cell communication and droplet interface bilayer (DIB) to look at antibiotic efficacy. onlinelibrary.wiley.com/doi/10.1002/...

Engineering a Biohybrid System to Link Antibiotic Efficacy to Membrane Depth in Bacterial Infections

A biohybrid system is presented for mimicking infections in both cellular and tissue contexts. Droplet interface bilayers (DIBs) are spatio-temporally controlled to enable antibiotic addition, withdr...

onlinelibrary.wiley.com

There are always many ways to look at your data.