My Op-Ed in the Pittsburgh Post Gazette was posted this morning. (Registration required, but I have posted a pdf on my dashboard) www.post-gazette.com/opinion/gues... 1/2

Jeremy M. Berg: Life-saving medicines begin in the basic research DOGE wants to stop funding

We should not lose sight of how wonderfully productive the biomedical research enterprise — now under threat — can be. The interplay between...

post-gazette.com

A huge privilege to see @drewweissmanlab.bsky.social, 2023 Nobel laureate for developing mRNA-LNP vaccines, at MSK speaking about their future in cancer vaccines and *in vivo* CAR-T (!!!) ...at the same time as NIH has been reportedly advising grant applicants to avoid mentioning "mRNA vaccines"...

I am so proud to share a major part of my graduate school research, published today in Science, where we use cell-free replication assays and cryo-EM to describe a central mechanism of eukaryotic DNA replication: www.science.org/doi/10.1126/...

G-quadruplex–stalled eukaryotic replisome structure reveals helical inchworm DNA translocation

DNA G-quadruplexes (G4s) are non–B-form DNA secondary structures that threaten genome stability by impeding DNA replication. To elucidate how G4s induce replication fork arrest, we characterized fork ...

science.org