Just came home from Oxford, thanks to @esrs.bsky.social In a nutshell: - we made strong advances in the making of the guide for rodent sleep research - I received Oxford's Cortex Club first prize for my research on dreams - we celebrated my birthday I'm so grateful to be part of this community.

A new "behind the paper" blogpost from @benbreant.bsky.social at @psl-univ.bsky.social on their recent publication dealing with the effects of the psychedelic 5-methoxy-N,N-dimethyltryptamine on mice brain: communities.springernature.com/posts/psyche...

Psychedelic 5-MeO-DMT induces dissociated state in mice

A new study published in Communications Biology shows how an injection of the psychedelic compound 5-MeO-DMT induces a dissociated brain state in mice, combining elements of sleep and wakefulness.

communities.springernature.com

Our paper with @vyazovskiy.bsky.social showcasing research conducted at @ox.ac.uk @oxforddpag.bsky.social is out! We describe the effects of the psychedelic 5-MeO-DMT on brain states and sleep via EEG, LFP & freely moving oculometry. Read more: www.nature.com/articles/s42... #EEG #neuroskyence

Vigilance state dissociation induced by 5-MeO-DMT in mice - Communications Biology

Administration of 5-MeO-DMT produces a dissociated brain state in mice, characterized by global slow-wave activity alongside behavioral wakefulness and marked pupil dilation.

nature.com

I passed my DPhil viva yesterday 🎉 A huge thanks to my examiner, Stuart Peirson and Matt Jones who've done an exceptional job, and a bigger thanks to my Dphil supervisors Vlad Vyazovskiy, David Bannerman and Trevor Sharp!

"Paradoxical wake" archive paper update, with new content & new prospects 🧪🧠 We show global slow waves after psychedelic administration + eye monitoring of freely-moving mice! A thrilling project with @vyazovskiy.bsky.social & @oxforddpag.bsky.social #EEG #sleep www.biorxiv.org/content/10.1...

Sleep-like state during wakefulness induced by psychedelic 5-MeO-DMT in mice

Psychedelics lead to profound changes in subjective experience and behaviour, which are typically conceptualised in psychological terms rather than corresponding to an altered brain state or a distinc...

biorxiv.org

The Paris Brain Institute has its start pack! go.bsky.app/Km2Qe2D Courtesy of @nikolaskaralis.bsky.social ! If you are from ICM and want to join, let him know! If you don't know ICM, you can find more info here: parisbraininstitute.org

An excellent read on hibernation from Vlad Vyazovskiy, and thoughts provoking as per usual! aeon.co/essays/how-a...

How animals learned to hibernate and why we can’t do it (yet) | Aeon Essays

Hibernation allows many animals to time-travel from difficult times to plenty. Could humans learn how to do it too?

aeon.co

Science & Academic peeps: You work with psychedelic? You know someone who work on psychedelics? Come my way! Let's expand our footprint on this network 🍄🧠🧪

We (S Sarasso, A Tzovara & K Peller) guest-edited a special issue for the Eur J of Neuroscience Measures & Mechanisms of Consciousness onlinelibrary.wiley.com/doi/toc/10.1... 🧠🧪💤 12 articles on sleep, dreams, mind blanking, disorders of consciousness & more! With a great cover from Nicolas Decat

Before working on dreams and human, I was studying psychedelic & sleep in rodents! In this preprint from my DPhil thesis, we show the occurence of an altered state with features of both sleep and wake in mice injected with 5-MeO-DMT. Stay tune, there is more to come! www.biorxiv.org/content/10.1...

“Paradoxical wakefulness” induced by psychedelic 5-methoxy-N,N-dimethyltryptamine in mice

Vigilance states – waking, slow-wave sleep (SWS) and paradoxical sleep, are thought to be controlled by several cortical and subcortical neuromodulatory circuits, among which the serotonergic (5-HT) s...

biorxiv.org