Richard Benninger
@bennyscience.bsky.social
Bioengineering to cure diabetes. Father of 2. Ski and hike in remaining time. Colorado. 🇺🇦 Benningerlab.com
Nice work Scott!
Scott Soleimanpour@soleimanpourlab.bsky.social · last yr.Type 2 diabetes is often considered a protein misfolding disease. But where are these toxic proteins found? 🤔 🚨In new work out today in @natmetabolism.nature.com, we show that mitochondrial protein misfolding (yes mitos🤯) leads to beta cell damage in T2D. 🚨 nature.com/articles/s42... 1/n
Check out this pre-print from Vira Kravets, Andraz Stozer and myself, for the influence of alpha cells on heterogenous islet Ca2+ responses, including first-responders and first phase timing/amplitude. Was great to be part of this! www.biorxiv.org/content/10.1...
Role of GLP1-receptor-mediated α-β-cell communication in functional β-cell heterogeneity.
While the islet β-cells were traditionally viewed as a singular functional entity, findings of 1970s and up until recent years, reveal that individual β-cells differ in their calcium dynamics and insu...
biorxiv.org
Apparently NIH is seeking to impose a standard 15% indirect cost rate going forward. That will be disruptive to say the least: grants.nih.gov/grants/guide...
NOT-OD-25-068: Supplemental Guidance to the 2024 NIH Grants Policy Statement: Indirect Cost Rates
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Supplemental Guidance to the 2024 NIH Grants Policy Statement: Indirect Cost Rates NOT-OD-25-068. OD
grants.nih.gov
Check out our ‘Paper of the Month’, led by Anne Gresch. Also coming to a Diabetes podcast soon! diabetesjournals.org/diabetes/art...
Resolving spatiotemporal electrical signaling within the islet via CMOS microelectrode arrays
Glucose-stimulated beta-cells exhibit synchronized calcium dynamics across the islet that recruit beta-cells to enhance insulin secretion. Compared to calc
diabetesjournals.org
Hello everyone- I work in diabetes research and will post about our research, but also like to follow and comment on English football (soccer) and American football (football).