That’s a wrap on our @embo.org #cryoFIB & #cryoET course! It was an incredible week of hands-on learning, collaboration, and shared expertise, made possible by dedicated organizers, incredible trainers, and an engaged group of participants.

Check out our latest exciting work on multidrug resistant A. baumannii biofilms

Debnath Ghosal@debnathghosal.bsky.social · 6mo ago

A. baumannii is one of the most notorious multidrug-resistant pathogens, capable of forming drug-tolerant biofilms that make infections exceptionally difficult to treat. But how are these complex microbial fortresses built? Just published in Nat Comms. pubmed.ncbi.nlm.nih.gov/41654547/

🌀 We solved the structure for T. denticola periplasmic flagella! I'm very happy to finally showcase this work. A huge collaborative effort between myself, @bindusmitapaul.bsky.social, @debnathghosal.bsky.social, Jack Kim, @banfieldlab.bsky.social, Eric Reynolds and the Chris Fenno lab. 🦠 Enjoy!

bioRxivpreprint@biorxivpreprint.bsky.social · 6mo ago

Structural basis for curvature generation and functional specialization in spirochete flagella https://www.biorxiv.org/content/10.64898/2026.02.04.703737v1

Wonderful spirochete asymmetric flagellar structural work by @lucatroman.bsky.social Grateful to be part of the story supported by @debnathghosal.bsky.social

Debnath Ghosal@debnathghosal.bsky.social · 6mo ago

📣 New paper alert! This is a story of molecular tricks that let spirochetes (spiral-shaped bacteria) drill through tissue. www.biorxiv.org/content/10.6...

🌀 How do spirochete bacteria swim through thick fluids like champions? We solved T. denticola flagella structure - asymmetric proteins expand one side, compress the other for perfect corkscrew motion! @debnathghosal.bsky.social 🔗 doi.org/10.64898/202... #StructuralBiology #CryoEM #Microbiology

📣 New paper alert! One of the most exciting projects we've done in recent years is now out on BioRxiv: "An Asgard archaeon from a modern analog of ancient microbial mats". Glimpse into early complex life! ❄️🦠 🔬🧬 www.biorxiv.org/content/10.1.... A thread...

An Asgard archaeon from a modern analog of ancient microbial mats

It has been proposed that eukaryotic cells evolved via symbiosis between sulfate-reducing bacteria and hydrogen-producing archaea. Here we describe a highly enriched culture of a novel Asgard archaeon...

biorxiv.org