How do #muscles repair after #injury and why does it fail in #disease and #aging? Submit your research on stem #cells, #inflammation, and metabolic #signaling in cardiac and skeletal muscle regeneration Submissions now open (Deadline: Jan 15, 2027) https://ow.ly/Omn550ZivZP
Biochemistry and Cell Biology
@biochemcellbio.bsky.social
Published since 1929, this @cdnsciencepub.com journal reports general biochemistry, incl. experimental research into cellular and molecular biology.
#Prions changed how we think about #biology: #proteins can misfold, spread, and reshape disease 🧠 Prion research matters, not just for rare #disorders, but for common neurodegenerative #diseases like #Alzheimer’s and #Parkinson’s https://ow.ly/oHiE50ZivYC
How sensitive are #meta-analyses to study inclusion and #heterogeneity? 🤔 Any changes in #study inclusion can shift #results, but interpretation depends on more than #statistics: including study #context, predefined #methods, and biological #plausibility https://ow.ly/rVvT50ZivVm
📢 Now accepting submissions to #Biochemistry and #Cell #Biology (BCB)! If you’re at an eligible institution, your #OpenAccess APCs may be fully waived Making publication completely free for authors https://ow.ly/kBRc50ZivSG Explore publishing with us today 🔬
#NowHiring! We’re seeking an Institutional Account Manager (UK) with experience in sales to grow subscriptions and support institutional partnerships across key markets. Apply now: https://ow.ly/5gBH50ZlCif
How do #cannabis derived terpenes affect nociception? In C. elegans, four terpenes were found to reduce heat-evoked pain responses 🧫 #proteomics reveals distinct signaling and stress-response pathways for each #compound https://ow.ly/PzHl50ZivS1
What makes #somatic #cells easier to reprogram? New study profiles fibroblast cell lines and shows that metabolic state, #DNA methylation, and histone marks define a “somatic-to-pluripotent-like” continuum that may predict reprogramming success https://ow.ly/qiaQ50ZivM1
How does PPP2R2B affect #breast #cancer progression? New study shows PPP2R2B activity can: • reduce #proliferation and #invasion • increase #apoptosis • enhance #ferroptosis via lipid ROS and #iron regulation A multi-layer tumor suppressor mechanism 🧬
CBP and p300 are key #epigenetic regulators often dysregulated in #cancer 🩺 New work shows CBP/p300 are upregulated in HCC, and blocking their activity triggers autophagy-driven #cell #death, partly through suppression of EPHA2. 🔬 https://ow.ly/ZZG150ZivKT
#Caspases don’t just execute #apoptosis Emerging evidence shows they also regulate lipid metabolism, redox stress, and metabolic dysfunction across #aging and #disease #Metabolism #CellBiology https://ow.ly/7rbO50ZivJP
One protein, many names OLA1 has been implicated in #cancer, oxidative stress, #mitochondrial #biology, #heart #disease, and neuronal differentiation; with growing evidence pointing to a central role in translation regulation #CellBiology #TranslationalResearch
Extended through 2028: Our Read and Publish agreement with the University of Oslo. Affiliated authors receive unlimited reading and no-cost open access publishing in our journal! Learn more ▶️ https://ow.ly/wlBj50YtxPj #AcademicPublishing #UIO Universitetet i Oslo
When you #publish in a #not-for-profit #journal, your article does more than share science 🧪 It helps fund #student #awards, trainee initiatives, and #community #conferences Keeping resources in the research ecosystem ♻️ https://ow.ly/4bxx50ZivTt Support your local journal 🧬
Classic #anticancer #drug meets a natural polyphenol 💊 Researchers investigated combining Actinomycin D with resveratrol and found enhanced #p53 activation, increased expression of p21/PUMA/GDF15, and stronger anti #cancer effects than either agent alone https://ow.ly/tpI050ZivJr
How do #breast #cancer cells maintain EGFR and GLUT1 activity? New study identifies O-GlcNAcylation as a key regulator of #protein stability, linking nutrient sensing, #phosphorylation, #ubiquitination, and metabolic reprogramming in #BreastCancer https://ow.ly/iIYg50ZivIT
Triple-negative #breast #cancer remains challenging to treat 🩺 New study identifies APT1/LYPLA1-dependent de-S-acylation as a potential therapeutic option, revealing subtype-specific regulation of protein acylation and cell-cycle control #BreastCancer https://ow.ly/xRvt50ZivHo
Regenerating #muscle isn’t just a #biology question—it’s a systems-level challenge 🧬⚡ New #collection invites work on #stem cells, #immune signaling, and t#herapeutic strategies for #cardiac and #skeletal repair 🔬 Deadline: Jan 15, 2027 https://ow.ly/cfsF50Z6nGe
Combination #therapies aren’t always straightforward ⚖️🧪 A new #study finds that actinomycin D + resveratrol enhances #anticancer activity in vitro via #p53 pathway activation—but does not improve in vivo #tumor suppression 🧫 https://ow.ly/WNN650Z6oCp
How should we be training #graduate #students in a world where #science moves faster—and #competition is sharper—than ever? 🧠⚡ We’re inviting editorials and perspectives on the future of grad student training in #biomedicine! 🧪 Got an #idea? Contact us: https://ow.ly/Ru6350Z6o40
Can we design #anticancer compounds that selectively target #tumor cells while sparing healthy ones? 🎯🔬 New work reports biphenyl–dihydropyrimidinone derivatives with selective #cytotoxicity and no detectable #genotoxic effects 💊 https://ow.ly/69XU50Z6o5z
Can #AI help detect #lung #disease faster and more efficiently? 🫁🤖 New work in #Biochemistry and #Cell #Biology introduces ChestCovidNet—a lightweight deep learning model for detecting #COVID-19, #pneumonia, and lung opacity from chest X-rays. https://ow.ly/k3g450Z6otF
Why do some #donor #cells reprogram better than others? 🧬🤔 New work explores “metaboloepigenetic” variability across bovine #fibroblast lines to help predict somatic cell reprogramming potential, a major step in improving #reproductive #technology! 🤰 https://ow.ly/3RNc50Z6om2
#Wound #healing is all about balance ⚖️🧫 A new study finds #lactoferrin supports #keratinocyte viability and fine-tunes #oxidative #stress responses without triggering uncontrolled proliferation 🧬 https://ow.ly/jLE450Z6oKS
From #Cannabis-derived terpenes to #worm #neurons 🧠🐛 New study shows Limonene, β-Caryophyllene, α-Humulene, and α-Myrcene reduce #pain responses in C. elegans, implicating TRPV-like channels in pain modulation! #Biochemistry #CellBiology https://ow.ly/biVB50Z6nm4
One #protein, many names 🧬 #OLA1 is universally conserved across all domains of #life, but its function has remained surprisingly elusive 🧫 This review unifies decades of #research and proposes a role in #ribosome-dependent #translation https://ow.ly/3Q0U50Z5O06
S-palmitoylation = reversible “#lipid switch” that controls #protein activity 🧬 🧫 This study improves detection of S-acylated proteins in Dictyostelium discoideum and identifies several key targets including adhesion and #stress-response #proteins 🔬 https://ow.ly/3SYc50Z5NZ8
#Science is getting more #complex—and no single #lab can keep up alone 🔬 This editorial explores how centralized core facilities may become essential “#research engines” for the next era of #discovery 🧬🏗️ https://ow.ly/CJEW50Z5NW8
Got a great story in #Biochemistry or Cell #Biology? 🧪 Don’t let it sit in your lab notebook, send it out into the world 🌍 🧬 Submit your work to Biochemistry and Cell Biology and share it with a global audience of researchers 🔬 https://ow.ly/72qa50Z6nhX
Same #enhancer, different #names = confusion in the field 🧬 New paper introduces a standardized enhancer nomenclature for #SOX2 to improve clarity and #reproducibility in gene regulation research 🔬 https://ow.ly/futM50Z5NSs