Jonathan Lebelt from our group @biomicat.bsky.social is on the stage presenting his latest results on deuterations using paired electrolysis ⚡️ @ the #internation Symposium on the Synthesis & Application of Isotopically labeled Compouns! Many thanks to the #IIS-ED for awarding the travel grant !

📢 Today’s highlight: editors from @synthesis1969.bsky.social and @synlettjournal.bsky.social are visiting University of Padova and giving fantastic talks. ✨ If you are nearby, come and see! It is a great chance to connect, learn, and be inspired. #Chemistry #Organic #Thieme #Synthesis #Synlett

📢 We are hiring! 🧑‍🔬👨🏽‍🔬DFG-funded RTG Ec=m2 is hiring 10 PhD scholars! Check out details at shorturl.at/Tue2T

What is responsible for the halogen specificity & is there a Substrate binding Site in #VHPOs? Learn more about this amazing enzyme class in our latest paper @naturecomms.bsky.social Congratulations to the Team! www.nature.com/articles/s41...

Unraveling the molecular basis of substrate specificity and halogen activation in vanadium-dependent haloperoxidases - Nature Communications

Vanadium-dependent haloperoxidases (VHPOs) are versatile enzymes that catalyze oxidation of halides followed by halogenation of electron-rich substrates, but the factors dictating substrate and haloge...

nature.com

We are hiring! Please share, thanks!

If you haven’t heard of us, we are a Canadian research group who work with fluorinated molecules 🤓 We love catalysis, and we don’t discriminate! (1/2)

BF3-Catalyzed Intramolecular Fluorocarbamoylation of Alkynes via Halide Recycling

A BF3-catalyzed atom-economical fluorocarbamoylation reaction of alkyne-tethered carbamoyl fluorides is reported. The catalyst acts as both a fluoride source and Lewis acid activator, thereby enabling...

pubs.acs.org

Yesterday we welcomed John Molloy from MPCI at Leipzig University! He gave an amazing & inspiring talk within our @crc-325.bsky.social lecture Series! Thanks John for being with us and sharing your research with us 🧪

📢If you like to graduate in an enthusiastic & interdisciplinary team and explore the realm of hydrogen isotope exchange to generate deuterated drug scaffolds then apply! We have an opening for a fully funded PhD position within the DFG Research Training Group 21721🧪Please RT

Great start into 2025!!! Thanks to the #VHPO Team in the Gulder lab. Check out our latest report on how employing enzymes in cascade reactions. pubs.acs.org/doi/10.1021/...

Chemoenzymatic C,C-Bond Forming Cascades by Cryptic Vanadium Haloperoxidase Catalyzed Bromination

Inspired by natural cryptic halogenation in C,C-bond formation, this study developed a synthetic approach combining biocatalytic bromination with transition-metal-catalyzed cross-coupling. Using the c...

pubs.acs.org

We are hiring (resharing appreciated)! Given recent successful grant applications (I got my SNSF Starting Grant 🚀), we are extending the LIAC team with multiple openings (PhD/postdoc) for 2025. Apply now (deadline: December 20th) by filling in this form: forms.fillout.com/t/eq5ADAw3kkus. #ChemSky

Thanks for the invitation by @CarlNising to visit the @BayerDialog site in Wuppertal and giving a @GDCh_aktuell lecture there yesterday! This was an amazing day!

There is nothing better for the 1st post than announcing the latest paper! 📢Check out our work in Angew. Chem. on hydrogen atom transfer in microstructured solutions! Special thanks go to Yang, Jonny & Martin from @biomicat.bsky.social and the Tonner-Zech and Asmis group 🎉 doi.org/10.1002/anie...

Hexafluorophosphate‐Triggered Hydrogen Isotope Exchange (HIE) in Fluorinated Environments: A Platform for the Deuteration of Aromatic Compounds via Strong Bond Activation

There is a perpetual need for efficient and mild methods to integrate deuterium atoms into carbon frameworks through late-stage modifications. We have developed a simple and highly effective syntheti...

doi.org