A Lenalidomide-Inducible Suicide Switch for Gene- and Cell-Based Therapy https://www.biorxiv.org/content/10.64898/2026.09.30.755642v1
Rational mRNA Structure -guided Attenuation Enables Embryo-safe in-ovo NDV Vaccination and Protection https://www.biorxiv.org/content/10.64898/2026.09.29.755556v1
Optimization of DNA Transformation in Mesoplasma florum and Identification of a Candidate Recipient Strain for Genome Transplantation https://www.biorxiv.org/content/10.64898/2026.09.29.755066v1
From Flocks to Swarms: Rewriting the Rules of Collective Cell Migration https://www.biorxiv.org/content/10.64898/2026.09.29.753501v1
Coupled enzyme discovery, evolution and synthetic yeast chassis adaptation for microbial biopolymer valorisation https://www.biorxiv.org/content/10.64898/2026.09.28.754783v1
Multichromatic Dynamic Control of Multi-Membered Microbial Consortia Compositions for Chemical Production https://www.biorxiv.org/content/10.64898/2026.09.28.754827v1
PRIME: A modular plasmid-based platform for continuous in vivo evolution across bacteria https://www.biorxiv.org/content/10.64898/2026.09.28.754915v1
Reassessing the contribution of the histone H3 tail to KRAB-DNMT3L-mediated epigenetic silencing https://www.biorxiv.org/content/10.64898/2026.09.24.753995v1
Thermodynamic, Electrochemical and Practical Constraints on Electromicrobial Formate Assimilation https://www.biorxiv.org/content/10.64898/2026.09.26.754500v1
Coupling a developmental promoter to CRISPR interference for Wnt pathway regulation in human pluripotent stem cells https://www.biorxiv.org/content/10.64898/2026.09.25.754435v1
Gene expression noise is reduced in communicating synthetic cell populations https://www.biorxiv.org/content/10.64898/2026.09.24.754039v1
Boolean Logic-responsive FRET Biosensors via Genetically Encoded Autonomous Compilation https://www.biorxiv.org/content/10.64898/2026.09.24.753966v1
AI-Guided Multi-Objective Engineering of Glucoamylase Enables Acidification-Free Starch Saccharification https://www.biorxiv.org/content/10.64898/2026.09.24.753989v1
Constructing Virtual Viruses in A Spatial Minimal Cell https://www.biorxiv.org/content/10.64898/2026.09.22.753465v1
Genetically inducible coordinators of cytokine signaling pathways for interrogating T cell motility https://www.biorxiv.org/content/10.64898/2026.09.21.753259v1
A Dynamically Regulated Designed IL-2 for Tumor-localized Signaling https://www.biorxiv.org/content/10.64898/2026.09.18.752703v1
Engineering Persistent and Rewritable Genetic Memory in Bacteria through Multiscale Plasmid Competition https://www.biorxiv.org/content/10.64898/2026.09.18.752696v1
Nanobody-Functionalized AAV achieves Promoter-independent Neuronal Targeting in the CNS https://www.biorxiv.org/content/10.64898/2026.09.18.752817v1
A step toward synthetic endosymbiosis: introducing Escherichia coli and the trypanosomatid endosymbiont Candidatus Kinetoplastibacterium crithidii into mammalian cells using a polyethylene glycol-based fusion protocol https://www.biorxiv.org/content/10.64898/2026.09.20.753003v1
Generative Neuromorphic Programming of Mammalian Cells https://www.biorxiv.org/content/10.64898/2026.09.18.752793v1
A Yeast Logic Toolkit for Fast and Efficient Assembly of Genetic Circuits https://www.biorxiv.org/content/10.64898/2026.09.21.753091v1
A Rationally Designed Transgene Drives CAR T Functional Persistence and Durable Regression of Solid Tumors https://www.biorxiv.org/content/10.64898/2026.09.18.752754v1
BRIDGE: A broad-host platform for interkingdom DNA delivery enabling the genetic domestication of phylogenetically diverse yeasts https://www.biorxiv.org/content/10.64898/2026.09.17.752325v1
The proteome as a whole: from a passive reflection of the transcriptome to an active cellular organizer https://www.biorxiv.org/content/10.64898/2026.09.15.751782v1
Firewalled synthetic commensal blocks horizontal gene transfer in the gut https://www.biorxiv.org/content/10.64898/2026.09.17.752456v1
Characterization of a fungal mixed-linkage glucan synthase https://www.biorxiv.org/content/10.64898/2026.09.17.752320v1
Data-driven predictive design of engineered living hydrogels https://www.biorxiv.org/content/10.64898/2026.09.17.752317v1
Programmable DNA Assemblies Reconstitute Supramolecular Protein Function https://www.biorxiv.org/content/10.64898/2026.09.15.751908v1
A methylome-guided toolkit for genetic engineering of the fast-growing cyanobacterium UTEX 3222 https://www.biorxiv.org/content/10.64898/2026.09.15.751560v1
Dynamic expression range expansion of ECF sigma factor-dependent synthetic regulons by promoter context engineering https://www.biorxiv.org/content/10.64898/2026.09.15.751809v1