On the Robustness of Biomolecular Systems to Perturbations in Translational Resources https://www.biorxiv.org/content/10.64898/2026.08.04.742896v1

Deep learning of dynamic signatures resolves mechanistic ambiguity in complex signaling networks https://www.biorxiv.org/content/10.64898/2026.08.04.742863v1

Mechanistic and machine learning models design human gut consortia that robustly inhibit Clostridioides difficile https://www.biorxiv.org/content/10.64898/2026.08.04.742850v1

Epithelial regulatory networks link non-coding genetic variation to clinical heterogeneity in ulcerative colitis https://www.biorxiv.org/content/10.64898/2026.08.04.742507v1

Observation-masked neural posterior estimation for heterogeneous epidemiological surveillance data https://www.biorxiv.org/content/10.64898/2026.08.03.742452v1

Scaling of Noise Under Resource Constraints in Gene Regulatory Motifs https://www.biorxiv.org/content/10.64898/2026.08.02.742368v1

Quantitative Modeling of TLR Signaling Reveals Missing Negative Feedback Guiding Identification of TANK-IKKε Checkpoint https://www.biorxiv.org/content/10.64898/2026.08.03.742528v1

Sepsis Subtypes in Blood and Liver Define Precision Strategy for CXCR2 Blockade https://www.biorxiv.org/content/10.64898/2026.08.03.740897v1

A benchmarking framework for single-cell genome-scale metabolic model construction https://www.biorxiv.org/content/10.64898/2026.08.02.742346v1

Genome-scale prediction of context-specific synthetic lethality beyond protein interaction networks https://www.biorxiv.org/content/10.64898/2026.07.31.742101v1

An organ-resolved rat FFPE phosphoproteome map enables directional kinase activity inference https://www.biorxiv.org/content/10.64898/2026.07.28.741173v1

The rabies virus interferon antagonist P protein selectively modulates interferon signalling to inhibit antiviral gene expression while supporting proviral gene expression https://www.biorxiv.org/content/10.64898/2026.07.30.737726v1

Deep Mechanistic Models reveal pathway-extrinsic drivers of mammary MAPK signalling heterogeneity https://www.biorxiv.org/content/10.64898/2026.07.30.741759v1

Steady state ratios in bipartite population models emerge through obligate cross-feeding https://www.biorxiv.org/content/10.64898/2026.07.29.741403v1

Exosome-Derived Proteomic Signatures Highlight Pathogenic Mechanisms in Moyamoya Disease https://www.biorxiv.org/content/10.64898/2026.07.30.741716v1

A Bayesian Study to Optimally Unveil LDH Kinetic Mechanisms In Vivo https://www.biorxiv.org/content/10.64898/2026.07.30.741466v1

The latent simplicity of microbial ecological interactions https://www.biorxiv.org/content/10.64898/2026.07.30.741683v1

Dynamics of a Hes1-Dll1 regulatory network in coupled muscle stem cells: stability, bifurcations, and coexistence of oscillatory states https://www.biorxiv.org/content/10.64898/2026.07.29.741250v1

Modulation of noisy gene expression by general sequestration mechanisms https://www.biorxiv.org/content/10.64898/2026.07.30.741692v1

A genetic switch involving EGR1 and EZH2 links aging and development across human tissues https://www.biorxiv.org/content/10.64898/2026.07.29.741427v1

Anticodon nucleotide modifications affect translational tuning by the ribosomal CAR surface https://www.biorxiv.org/content/10.64898/2026.07.29.740946v1

Covariant Biochemical Systems Theory: cBST1~cBST3 Descriptors and Quantitative Validation https://www.biorxiv.org/content/10.64898/2026.07.26.732504v1

Coevolution-driven reconstruction of multi-taxa siderophore interaction networks reveals topological diversity of microbial exploitation https://www.biorxiv.org/content/10.64898/2026.07.28.741125v1

Light-dependent metabolism and proteome allocation in Synechocystis sp. PCC 6803: an enzyme-constrained metabolic model across light intensities https://www.biorxiv.org/content/10.64898/2026.07.28.741177v1

Coordinated immune, chloroplast and chemical defences underpin multilayered resistance to barley yellow dwarf virus and its aphid vector associated with the Hordeum bulbosum-derived Ryd4 introgression in barley https://www.biorxiv.org/content/10.64898/2026.07.28.741184v1

Directing hierarchical cell fate decisions through sequential pulses of minimal signaling alphabets https://www.biorxiv.org/content/10.64898/2026.07.28.741174v1

Structural characterization of stochastic detailed balance in chemical reaction networks https://www.biorxiv.org/content/10.64898/2026.07.24.740452v1

A targeted plasma-proteomic axis separates autoimmune thyroid disease from growth-hormone deficiency https://www.biorxiv.org/content/10.64898/2026.07.27.741048v1

Proteome-wide QTL mapping enables gene-protein-phenotype metabolic network construction in a genetically diverse MASLD mouse model https://www.biorxiv.org/content/10.64898/2026.07.26.740836v1

Cross-Species Efficacy of Combinatorial Gene Therapy for Osteoarthritis and Correction of Neuro-Inflammatory Pain Mechanisms https://www.biorxiv.org/content/10.64898/2026.07.27.740924v1