Introducing the ActualHCA Event Monitoring Tool for transforming continuous data into actionable insights! This new tool automatically identifies when behavior and/or temperature data move outside user-defined ranges. #BehavioralResearch See ActualHCA: bocascientific.com/products/act...

Researchers leveraged our Agrisera IDH #antibody to validate successful isolation of plant-derived #mitochondria (P-Mit). They showed that P-Mit transfers can improve microglial function. See our line of Agrisera antibodies here: bocascientific.com/brands/agris... link.springer.com/article/10.1...

A team of researchers @liganlab.bsky.social identified an inflammatory pathway as a major contributor to the progression of Dravet syndrome. Blocking this #molecular pathway could lead to new therapeutic strategies for #epilepsy disorders. #Neurology www.nature.com/articles/s41...

cGAS-mediated type I IFN signaling contributes to disease progression in drug-refractory epilepsy - Nature Neuroscience

Huang et al. found that stressed neurons release DNA that activates the immune sensor cGAS, driving inflammatory responses that worsen seizures and mortality in Dravet syndrome. Blocking cGAS interrup...

nature.com

Utilizing various techniques including #CRISPR, researchers found a #gene that helped anoles survive hurricane winds by shrinking some of their toes, making their grip stronger. This huge discovery into their #genetics offers insights into #evolution. www.science.org/content/arti...

Gene may help lizards get a grip in hurricane-force winds

“Huge” new study of Caribbean anole populations catches evolution in real time

science.org

Receive 15% off @agrisera.bsky.social Environmental Stress #Antibodies now through September, 2026! These high-quality antibodies are ideal for #proteins involved in plant stress response. #PlantResearch #PlantBiology See our Agrisera Antibodies here: bocascientific.com/brands/agris...

Lake Memphremagog is home to brown bullhead catfish, with nearly one-third spotted with an inky-black #cancer. This rare disease appears to be a single cancer that has spread from fish to fish, leading to new research surrounding transmissible cancers. www.science.org/content/arti...

Contagious fish cancer overruns New England lake

Catfish melanomas are the first example of a transmissible cancer in fish, genetic studies reveal

science.org

Researchers used our Easy-Spin Total RNA Extraction Kit to extract RNA from fetal lung explants. qRT-PCR showed gene expression changes linked to development and cell senescence after cannabinoid and nicotine exposure. See the kit: bocascientific.com/products/172... www.nature.com/articles/s41...

Scientists have leveraged AI models to create synthetic #CRISPR proteins that efficiently edit the #genome more than their natural counterparts. These synthetic CRISPR systems could lead to discoveries in many different fields. www.nature.com/articles/d41...

CRISPR gets a power boost from AI-designed ‘molecular scissors’

Researchers used artificial intelligence to design functional CRISPR enzymes not seen in nature.

nature.com

The largest study of the #gene expression profile of human endometrial #epithelial progenitor #cells & #mesenchymal stem cells was conducted by @gargettlab.bsky.social. The cells transition to more mature cells that regenerate to prepare the uterus for pregnancy. www.cell.com/stem-cell-re...

Molecular signature of human endometrial stem/progenitor cells at the single-cell level

Gargett and colleagues provide a molecular signature of human endometrial stem/progenitor cells by enriching 4 stem/progenitor populations from hysterectomies, using known markers, for scRNA-seq analy...

cell.com

A team of researchers @onjcri.org.au have discovered that even a small reduction in the #protein BECLIN1 can lead to a significant increase in gut inflammation. This protein plays an important role in clearing out damaged #cells and #autophagy. www.nature.com/articles/s41...

Our new CRISPR & Gene Expression range from Cellecta delivers innovative tools and workflows for #gene editing, helping researchers achieve efficient and reliable results across a wide range of applications. #CRISPR Learn more here: bocascientific.com/products/mol...

A new study from Italy suggests dried meat from pacific oysters can suppress inflammation in the intestines of humans. Naturally occurring #bioactive substances with anti-inflammatory properties can assist in management of chronic #inflammatory diseases. medicalxpress.com/news/2026-07...

Oyster meat may provide a sustainable solution for intestinal inflammation

Ongoing research provides evidence that readily available and sustainable oyster meat extract may have powerful anti-inflammatory effects on human intestinal cells.

medicalxpress.com

Researchers discovered that sugars in breastmilk, human milk oligosaccharides (#HMOs), influence which #bacteria thrive in the gut during the transition to solid food. The period combining breast milk and solid food promotes maturation of gut #microbiota. www.nature.com/articles/s41...

Celebrate lab innovation with our HPLC columns & buffers for reliable DNA and RNA purification, and HANABI Avatar™ Organoid Growth Media for 3D culture applications. These solutions from ADS Biotec are designed to streamline your workflows! Learn more: bocascientific.com/brands/ads-b...

Researchers were surprised to discover that the protein CBX7 can activate inflammatory #genes & help sustain #immune system signaling that contributes to #asthma. This discovery provides new insight into the biological processes of asthma & allergies. www.science.org/doi/10.1126/...

CBX7 functions as a methylation-dependent inducer of gene transcription and regulator of cytosolic signaling in lymphoid cells

CBX7 positively regulates cytokine expression by recruiting transcriptional activators and enhancing ERK1/2 activation in T cells.

science.org

Researchers used GRiSP Xpert reagents for RT-qPCR analysis of three key #genes involved in proline #metabolism under osmotic stress, showing complex regulation. #PCR See GRiSP Xpert Reagents: bocascientific.com/products/pcr... www.sciencedirect.com/science/arti...

Two people with a rare #autoimmune disease have been in remission for more than 15 years after a #stemcell transplant. The condition is neuromyelitis optica spectrum disorder (NMOSD), a potentially fatal disease effecting the spinal cord, eyes and brain. www.nature.com/articles/d41...

Stem cells banish severe autoimmune disease for 15 years

Two people were the first to receive the therapy for a condition that damages the spinal cord and optic nerve.

nature.com

A team at Mass General Hospital tracked the brain #cells responsible for how sentences are built before spoken. By observing the #neurons in the frontotemporal cortex, cells act as specialized linguistic building blocks, caring if its a noun or ending of a phrase. www.nature.com/articles/d41...

How the brain builds sentences, neuron by neuron

Neural maps reveal the specialized cells that produce speech.

nature.com

In the largest #IBD trial, researchers identified a #genetic marker associated with more severe ulcerative colitis & Crohn's disease. A combination within the HLA-DRB1 #gene, suggests genetic testing could identify IBD patients at risk of severe disease. www.thelancet.com/journals/lan...

HLA-DRB1*01:03 in patients with inflammatory bowel disease: a genotype–phenotype association study

HLA-DRB1*01:03 emerges as a genetic determinant of severe disease in both patients with Crohn's disease and patients with ulcerative colitis. Although further validation is needed, assessing HLA-DRB1*...

thelancet.com

A key puzzle piece as to how the Venus flytrap snaps shut so quickly has been discovered. Once an insect crawls into the flytrap's maw, #cells on the outer surface of the hinged leaf soften, allowing the leaf to change shape and hinge shut. www.nature.com/articles/d41...

Revealed: how Venus flytraps snap shut with astonishing speed

Softening of the cells on the outermost surface of the trap lets the plant move at a breakneck pace.

nature.com

Researchers @ucsdmedschool.bsky.social conducted a large #genetic study identifying key #biological drivers of cocaine addiction. This potential new treatment targets the liver rather than the brain, suggesting addiction involves the whole body. today.ucsd.edu/story/geneti...

Genetic Mapping Identifies Potential New Targets for Cocaine Addiction

UC San Diego researchers have identified genetic drivers of cocaine addiction, uncovering a potential new treatment target in the liver. This large-scale study maps how metabolism influences addiction...

today.ucsd.edu

Our easy-to-use BuccalFix Plus DNA Isolation Kit is specifically designed for use with our BuccalFix Stabilization buffer to achieve DNA with high yields & purity. The kit comes with all the reagents required to purify #DNA stored in BFX with ease. See it: bocascientific.com/products/bfp...

A team of researchers at NIEHS, identified a #genetic link between the lung #microbiome & Idiopathic pulmonary fibrosis (IPF). They found TLR5 receptors in airway cells are activated in response to lung injury, stopping the overgrowth of harmful bacterium. www.nature.com/articles/d41...

This mysterious lung disease affects millions of people — but a drug tested in mice shows promise

The therapy activates a protein that could stop pulmonary fibrosis from progressing.

nature.com

A new SMM-seq study quantifies ENU-induced somatic mutations, reinforcing the link between #DNA repair error rate and species lifespan. Our SD polymerase enabled rolling-circle amplification for ultra-accurate detection. See it: bocascientific.com/products/223... www.sciexplor.com/geromedicine...

Researchers at @uclahealth.org found that #cancer drug selpercatinib can reduce the risk of lung cancer returning in patients with a rare #genetic subtype of early-stage non-small cell lung cancer. This could offer a new treatment option. #CancerResearch www.nejm.org/doi/10.1056/...

Selpercatinib in Early-Stage RET Fusion–Positive Non–Small-Cell Lung Cancer | NEJM

Selpercatinib, a highly selective, potent, and central nervous system–penetrant rearranged during transfection (RET) inhibitor, is approved for RET fusion–positive advanced or metastatic non–small-...

nejm.org

A team at Northwestern Medicine found that L-2-hydroxyglutarate, a compound associated with rare #metabolic disorders, acts as a signaling #molecule and helps regulate #gene expression. Some metabolites thought to be toxic may have crucial #physiologic functions. www.nature.com/articles/s41...

Mitochondrial l-2-hydroxyglutarate is a physiological signalling metabolite - Nature

l-2-Hydroxyglutarate is identified as a legitimate physiological signalling metabolite, and control of its levels is essential for postnatal growth and survival and correct renal development and funct...

nature.com

Researchers @meduniwien.ac.at identified a previously underestimated mechanism by which breast #tumors evade the immune system. The process was given the name Sialylation, and involves a sugar modification on the surface of tumor cells, impairing communication. #cancer www.nature.com/articles/s41...

Agrisera Antibodies offer reactivity to thousands of plant & algal species. These high quality, off-the-shelf antibodies are validated in at least two independent laboratories and are ideal for a wide range of research areas! #Photosynthesis #PlantBiology bocascientific.com/brands/agris...

Researchers @hopkinsmedicine.bsky.social found #genes from one parent can sometimes silence those inherited from the other, with effects that could persist for generations! It is called #paramutation and challenges the conventional view of inheritance. #genetics www.science.org/content/arti...

Can one parent silence the other’s genes? Natural ‘paramutations’ found in mice

Odd phenomenon first seen in plants could explain puzzling disease inheritance patterns

science.org

A team @columbiamed.bsky.social found the #protein NFIL3 plays a role in causing CAR T-cells to become "exhausted" and lose effectiveness. When NFIL3 is deactivated, they are functional for longer, proliferate more effectively, & have stronger antitumor activity. medicalxpress.com/news/2026-05...

Study identifies key protein in immune cell exhaustion in cancer immunotherapy

CAR T-cell therapy is considered a milestone in personalized cancer treatment. In this approach, a patient's own immune cells are genetically modified to recognize and destroy tumor cells. While it ha...

medicalxpress.com