Tessera

Homologous series of previously overlooked polymerization byproducts (H-PFCAs) detected near fluoropolymer production plant using #SIRIUS6. #SIRIUSDiscoveries #PFAS #Fluoropolymers 💡 Blog post: buff.ly/P9grMJQ (3 min) 📄 Publication: buff.ly/a960M9n

Using #SIRIUS6, researchers found the #Biopesticide 6-PP to be produced via the polyketide biosynthesis pathway in Trichoderma fungi. This finding may pave the way for developing improved biocontrol agent. #SustainableAgriculture 💡 SIRIUS discoveries: buff.ly/HP0dTWO 📄 Publication: buff.ly/J5JE4Tk

Metabolic adaptations of a salt-tolerant willow are specific to the plant organ and the salt anion. The researchers used #SIRIUS6 to identify the chemical structures of unknown compounds from mass spectrometry data. 💡 SIRIUS discoveries: buff.ly/HP0dTWO 📄 Publication: buff.ly/plLgOGE

#NonTargetedAnalysis #ChemicalClassification with #SIRIUS6 identifies cell surface glycans & membrane lipids as influential drivers of adaptation to heat stress in rice coral hosting thermosensitive and thermotolerant symbionts. 💡 SIRIUS discoveries: buff.ly/HP0dTWO 📄 Publication: buff.ly/KeqUClP

Unlocking the secrets of healing mushrooms 🍄 #SIRIUS6 was instrumental in detailing the metabolic basis for the production of sesquiterpenoids in the #MedicinalMushrooms Sanghuangporus. #SIRIUSDiscoveries #NaturalProducts 💡 More SIRIUS discoveries: buff.ly/HP0dTWO 📄 Publication: buff.ly/RDAMNtB

Hidden Players in Drug Efficacy: Using #SIRIUS6, researchers decoded the crucial role of the gut microbiome in altering the chemical structure and efficacy of GPCR drugs. 💡 Blog post: buff.ly/WtrJf2m (5 min) 📄 Publication: buff.ly/8o1ekPv #SIRIUSDiscoveries #DrugMetabolism #PersonalizedMedicine

Based on this tutorial our software #SIRIUS6 plays a significant role in prioritization strategies for #NonTargetScreening in environmental samples by generating molecular fingerprints which are used for compound identification or toxicity prediction. 📄 Read the tutorial: buff.ly/M9gNmBR

🌱 The quest to enhance long-term soil carbon storage 🌏 #SIRIUS6 #CompoundClassPrediction was essential for annotating 80% of the previously unknown metabolite features of tall wheatgrass root exudates. 💡 More #SIRIUSDiscoveries: buff.ly/HP0dTWO 📄 Publication: buff.ly/sYB1nPm

How can we assess the risk of a compound we can't even name? SIRIUS molecular fingerprints serve as crucial inputs for predictive models, such as #ToxicityPrediction, even when the exact identity of a compound is unknown. 📄 doi.org/10.1016/j.en... #SIRIUSFacts #SIRIUS6 #NonTargetAnalysis

#SIRIUS6 in a #NonTargetedAnalysis to identify unknown chemical compounds with potential estrogenic activity to investigate the link between #DrinkingWater #contaminants and #BreastCancer incidence. ▶️ Try SIRIUS now: buff.ly/K8wQ3ER 💡 Original publication: buff.ly/SZ2LPbp #SmallMoleculeID

Untargeted #metabolomics using #SIRIUS6 is mapping the #InternationalSpaceStation Most extensive look yet at the microbial and chemical landscape of the ISS. 💡 Blog post: buff.ly/nGt934u (5 min) 📄 Original publication: buff.ly/s8BBclb ▶️ Try #SIRIUS6 now: buff.ly/K8wQ3ER #SIRIUSDiscoveries

#SIRIUS6 compound class prediction helps to validate ethanol extraction for human faecal #metabolomics as a valid, safer, and more economical alternative to the common methanol extraction. ▶️ Try SIRIUS now: buff.ly/x7dNWAR 📄 Publication: buff.ly/cGkUOyi #SIRIUSDiscoveries #Microbiome

New study from the long-running @jena-experiment.bsky.social challenges core ecological assumption: that in a diverse ecosystem, plants can save energy on defenses and focus on growth. 📄 Blog feature: buff.ly/LgCEGpL 📄 Publication: buff.ly/u6lzwUe #SIRIUS6 #SIRIUSDiscoveries #NonTargetedAnalysis

#MultiOmics study revelead link between microbial community structure and chemical profile of the surface #metabolome in Saccharina latissima. 💡 Check out more SIRIUS discoveries: buff.ly/aI5m3ps 📄 Paper: buff.ly/uUT34E0 #SIRIUSDiscoveries #MarineBiology #Microbiology #ChemicalEcology

Green solvents can effectively extract diverse bioactive compounds from Melissa officinalis leaves. SIRIUS was employed for the comprehensive annotation of metabolites, resulting in the putative annotation of 444 metabolites. 💡 More #SIRIUSDiscoveries: buff.ly/aI5m3ps 📄 Paper: buff.ly/AEpoIFv

In this #NonTargetedAnalysis utilizing SIRIUS, researcher successfully identify common and previously unreported chemical contaminants in human milk, including novel parabens. Blog post: buff.ly/0vQizvG Paper: buff.ly/Mg8axQF #SIRIUS6 #StructureElucidation

Using SIRIUS, researcher identified anti-viral compounds in Caesalpinia mimosoides hydroethanolic extract that help to inhibit influenza A virus by targeting two critical viral proteins. ▶️ Try SIRIUS: buff.ly/x7dNWAR 💡 More SIRIUS discoveries: buff.ly/aI5m3ps 📄 Original publication: buff.ly/qR8zEvb

New review on #MassSpectrometry-based #Metabolomics for #NaturalProductResearch positions #SIRIUS6 as the leading suite for molecular structure annotation. ▶️ Try SIRIUS now: buff.ly/x7dNWAR 📄 Read the full review: buff.ly/0mMyixO #StructureElucidation #SmallMoleculeID #MachineLearning

MCheM integrates online chemical labeling reactions directly into the LC-MS/MS workflow to provide structural information which is fed into #SIRIUS6 via @mzmine.bsky.social to significantly constrain the molecular structure search space and boost annotation accuracy. Learn more: buff.ly/iib0L6I

🧠 ✏️ Your chemical intuition, now integrated into #SIRIUS6. Have you tried the new Structure Sketcher yet? ▶️ Watch our new YouTube tutorial to learn how to use the Structure Sketcher and elevate your annotation process: www.youtube.com/watch?v=_byB... #HowToSIRIUS #SmallMoleculeID #MassSpec

Do you ever look at the best hit from a structure database search and instantly know how to improve it? In #SIRIUS6, your chemical intuition just got a powerful new tool: the Structure Sketcher. buff.ly/c4cfGvW #HowToSIRIUS #SmallMoleculeID

🌍✨We're blown away by the growth of the SIRIUS community! We're seeing unprecedented usage and impact of our software across the globe. ⬆️ 1.000.000.000+ processed queries 👥 1.500+ monthly active users 🙏 Thank you for being part of this journey. We're excited to see what you discover next!