Department of Plant Sciences Cambridge

@camplantsci.bsky.social

News, research and updates from the Department of Plant Sciences at the University of Cambridge.🌱🔬 🌾 https://www.plantsci.cam.ac.uk/

Three distinct nematode ‘transcriptional programmes’ are evident, and we find that effectors are neither uniformly deployed across hosts nor across groups. We show that there is no widespread core gall transcriptome at 25 DPI. We therefore proposed a model described as ‘all roads lead to Rome’.

The host range paradox of <fi>Meloidogyne incognita</fi>: a physiological and transcriptomic analysis of nine susceptible interactions across six plant orders

Phylogenetic distance of host does not explain phenotypic differences of Meloidogyne incognita parasitism at 25 dpi.

doi.org

Finally out! A long-standing question is how M incognita can infect representatives from most orders of flowering plants, covering > 3000 spp. Our data show that phylogenetic distribution does not explain the phenotypic distribution of parasitism. Check it here: doi.org/10.1111/nph....

The host range paradox of <fi>Meloidogyne incognita</fi>: a physiological and transcriptomic analysis of nine susceptible interactions across six plant orders

Phylogenetic distance of host does not explain phenotypic differences of Meloidogyne incognita parasitism at 25 dpi.

doi.org

Excited to share this story in its final form, now published in ACS Synthetic Biology. #PlantBiology #Synbio pubs.acs.org/doi/10.1021/...

Engineering Auronidin Production in Marchantia polymorpha Enables a New Class of Plant-Derived Textile Pigments

Plant-derived pigments offer sustainable alternatives to synthetic colorants, yet their practical deployment in textiles is limited by restricted chemical diversity and low abundance. Liverworts represent a source of diverse chemical compounds, and the model liverworts Marchantia polymorpha are emerging as chassis for bioengineering and synthetic biology. Here, we report the biotechnological application of auronidins, a rare class of flavonoid pigments, as textile dyes. Using M. polymorpha, we engineered enhanced auronidin production through controlled expression of the R2R3-MYB transcription factor MpMYB14. We systematically benchmarked constitutive and inducible gene expression systems, including heat-shock, glucocorticoid receptor, and β-estradiol (XVE) circuits, identifying inducible strategies that decouple biomass accumulation from secondary metabolite production while achieving high pigment yields. Extracted auronidins were used to dye cotton yarn directly, demonstrating the feasibility of auronidins for textile dyeing. Our results establish M. polymorpha as a versatile plant chassis for programmable secondary metabolite production and introduce auronidins as a promising natural pigment platform for sustainable textile biotechnology.

pubs.acs.org

Facundo Romani@fromani.bsky.social · 6mo ago

Marchantia might seem an unlikely biotech crop, but it’s worth trying. In Aurore’s thesis, we pushed this concept by engineering the auronidins with MpMYB14 and using the pigments to dye cotton. It ended up giving a very unique and beautiful product. #PlantScience www.biorxiv.org/content/10.6...

A recurring signature: NLS+nucleic-acid-binding domains+activation domains. Hallmarks of transcription factors. It's not just symbionts. The same architecture appears in gall-inducing Pantoea effectors, proven DNA-binding transcriptional activators. (5/6)

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Excited to give a talk and serve as a session chair at #PlantBiology2026! I'll be chairing the Genes/Genomes: Regulatory & Transcriptional Networks session. Looking forward to engaging discussions and catching up with friends. If you're attending, let me know—happy to meet up! 🌱

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