Review alert! take a look at this article we wrote with Daniela Vidal and @italoacastro.bsky.social discussing the Implications of RNA virus persistence for post-acute sequelae and chronic inflammatory syndromes www.nature.com/articles/s41590-026-02577-5

Implications of RNA virus persistence for post-acute sequelae and chronic inflammatory syndromes - Nature Immunology

López and colleagues review recent evidence of RNA virus persistence and the associated consequences in terms of post-acute sequelae or chronic inflammatory syndromes.

nature.com

Our lab is hiring an enthusiastic and motivated research specialist to study host-pathogen interactions in the context of S. aureus infection. For more information, see below: Lab website: www.reyesruizlab.org jobs.wisc.edu/jobs/researc...

Research Specialist - Madison, Wisconsin, United States

Current Employees: If you are currently employed at any of the Universities of Wisconsin, log in to Workday to apply through the internal application process.Job Category:Academic StaffEmployment Type...

jobs.wisc.edu

BWF Announces the 2026 Investigators in the Pathogenesis of Infectious Disease www.bwfund.org/news/bwf-ann... #bwfpath

BWF Announces the 2026 Investigators in the Pathogenesis of Infectious Disease - Burroughs Wellcome Fund

DURHAM, N.C. – The Burroughs Wellcome Fund is pleased to announce the recipients of the 2026 Investigators in the Pathogenesis of Infectious Disease (PATH) awards, recognizing assistant…

bwfund.org

3. Yanling Yang as part of a team with Emna Achouri and others used scSeq to map the transcriptional response of an infected cell population. They described a layered antiviral response within the first 24 h of infection initiated by copy-back containing cells... doi.org/10.1371/journal.ppat.1014184

Detailed single-cell mapping of the transcriptional response to a virus infection driven by copy-back viral genomes

Author summary Viruses often produce non-standard viral genomes during replication. One important class of these molecules, called copy-back viral genomes (cbVGs), is known to strongly stimulate antiv...

doi.org

2. Matt Hackbart studied the immunostimulatory motifs of the prototype cbVG-546 from Sendai virus and identified critical nucleotides at the tip of the structure that improve RIG-I signaling: rnajournal.cshlp.org/content/earl...

I haven't been out here much this year, but we have several cbVG papers out! check them out: 1. Yanling Yang generated several recombinant cbVG-free SeV stocks and studied the populations of cbVG as they were generated ...she found some very interesting population dynamics: doi.org/10.1128/jvi....

Variable and conserved features of copy-back viral genome populations generated de novo during Sendai virus infection | Journal of Virology

Copy-back viral genomes (cbVGs) are generated during infection when the polymerase drops off from the template and reattaches to the nascent strand, and they are major drivers of antiviral immunity. H...

doi.org

Check out our most recent study featured on the cover of the December issue of the @amjtransplant.bsky.social Big shoutout to the Departments of Surgery, Pediatrics, Pathology & Immunology at WashU for the great collaborative work! #virology #transplant #lung

American Journal of Transplantation@amjtransplant.bsky.social · 11mo ago

🚨 Editor’s Choice 🚨 "Tolerogenic lung allograft microenvironment suppresses pathogenic tissue remodeling following respiratory virus infection in mice," by Ítalo de Araújo Castro et al. www.amjtransplant.org/article/S160...

New paper by @italoacastro.bsky.social is out! In collaboration with the Kreisel Lab from the Department of surgery, we studied the impact of a lung viral infection in transplanted lungs...with some unexpected results! Take a look: doi.org/10.1016/j.aj...

As always, Ted Chiang is great in this interview. cdh.princeton.edu/blog/2025/08...

Congratulations to SB Pye and team for validating several paramyxovirus copyback genomes by direct RNA-Seq (no PCR involved). Specially cool are species formed between nucleotide 1 of the genome and a sequence close to the trailer..these are real products! journals.asm.org/doi/10.1128/...

Validation of diverse and previously untraceable Sendai virus copyback viral genomes by direct RNA sequencing | Journal of Virology

Most viruses of the order Mononegavirales have been demonstrated to naturally generate copyback viral genomes. These genomes are critical determinants of infection outcomes; they interfere with standa...

journals.asm.org

The Sengupta lab is seeking research technicians to join its team. Ideal candidates must possess a passion for research and exceptional communication skills. Both early-career and experienced candidates are welcome. Email SenguptaS@chop.edu with CV and letter of interest with goals and expectations.

Now you see me, now you don’t: What and how viral RNAs are detected by cytoplasmic pattern-recognition receptors

Now you see me, now you don’t: What and how viral RNAs are detected by cytoplasmic pattern-recognition receptors

In a recent issue of Molecular Cell, Genoyer et al. show that during West Nile virus infection, escaped, cytoplasmic, anti-genomic negative-sense viral RNA triggers an antiviral response via RIG-I activation. Flaviviruses typically hide −vRNA in replication compartments to avoid detection, but some −vRNA leaks, possibly aided by viral capsid proteins.

dlvr.it

Vergüenza ajena…que horror tanta ignorancia en este país que se supone “líder”

Carl Zimmer@carlzimmer.com · 2y ago

NIH to ax grants on vaccine hesitancy, mRNA vaccines. www.science.org/content/arti...

With this kind of people, bending over won’t help. Also, this IS the time to stand up for principles, particularly academic freedom, and… free speech. theintercept.com/2025/03/08/c...

Columbia Bent Over Backward to Appease Right-Wing, Pro-Israel Attacks — And Trump Still Cut Federal Funding

Columbia bent over backward to appease right-wing, pro-Israel attacks on Gaza protesters — and Trump still cut the school’s federal funding.

theintercept.com

Pretty nice turnout at Jefferson City, MO’s capitol for #StandUpforScience today given how far it is from the closest large cities. Thanks to the organizers and to all those who drove 2h to make it there!

Friends, we need 50 subscribers to our YouTube channel to be able to live stream today’s Birmingham Stand Up For Science march! Anyone willing to subscribe is greatly appreciated! youtube.com/@standupfors...

Stand Up for Science Alabama

youtube.com

SO MANY STAND UP FOR SCIENCE EVENTS TO CHOOSE FROM—153 and COUNTING! To get more information on our local events and to register your own, head to www.standupforscience2025.org/local-event-information/ ☀️⬇️🌎

Our colleges & universities should encourage, not suppress, open & vigorous dialogue & debate about even the most deeply held beliefs. Trump’s threats against student protesters are antithetical to the mission of higher education. We strongly condemn them. www.aaup.org/news/threats...

On Friday, we Stand Up for Science in locations Nationwide (& internationally!) to support science as a public good that benefits everyone. Join us! Visit www.standupforscience2025.org for more information & other ways to get involved ☀️

For the sake of humanity, it's time to get out there and Stand Up For Science!! Spread the word!

I got laid off today, with the rest of 18F. 18F was an elite federal software shop. We made gov't websites work better, more efficiently for the American people. We saved taxpayers from getting screwed over by contractors. And were fired for it. We made this website to tell our story: 18f.org

Rubella is a major cause of birth abnormalities if a pregnant woman gets exposed. That’s why we vaccinate against it. What about all those worries for unborn babies now???

Steven Pergam, MD, MPH@pergamic.bsky.social · 2y ago

Rubella on your dance card? Maybe it should be. www.tpr.org/education/20...

ATTENTION The Washington Post is collecting data about funding issues. Please consider contributing. thewashingtonpost.formstack.com/forms/scient...

Very grateful to our @scripps.edu President/CEO Pete Schultz, for this OpEd in @sandiegouniontribune.com on the key importance of research institutions in U.S. biomedical science and how federal support is critical to fuel new discoveries and medicines. www.sandiegouniontribune.com/2025/02/25/o...

Opinion: Science funding cuts are based on flawed logic. Here’s the truth.

Earlier this month, the National Institutes of Health issued supplemental guidance indicating it would immediately impose a 15% cap on indirect costs for research grants, an unprecedented and abrup…

sandiegouniontribune.com

STAT story is up about study section restart. www.statnews.com/2025/02/24/s...

Some NIH study sections will resume reviewing grants, but final funding decisions are still in limbo

While some NIH study sections will resume, advisory council meetings, which make final funding decisions, seem to still be held up.

statnews.com

Some good-ish news from NIH “Federal Register notices for study sections run by CSR (but not those by ICs) will start being permitted again” As far as I know, the timing for this is not clear, but I will be checking the Federal Register.

a man in a red suit and tie is holding a piece of paper that says breaking news on it

ALT: a man in a red suit and tie is holding a piece of paper that says breaking news on it

media.tenor.com

www.aei.org/economics/wh...

A US Senator Joins the Fray. Thank you @murray.senate.gov ! More of this, please! www.murray.senate.gov/senator-murr...

Senator Murray Blasts Trump & Elon for Illegally Paralyzing Lifesaving Research Again, Threatening to Extinguish Ongoing and Groundbreaking Work - Senator Patty Murray

ICYMI: Murray Blasts Trump and Musk Decimating HHS, Risking Americans’ Health and Livelihoods Washington, D.C. — U.S. Senator Patty Murray (D-WA), Vice Chair of the Senate Appropriations Committee and...

murray.senate.gov

This list with sources telling the reality of what is going on should be spread widely. Thanks for putting it together.

Dr. Headbutt 🌈🧪@nicoleackermans.com · 2y ago

Sources NIH grants still paused archive.ph/2025.02.20-2... NSF cuts (not primary source) nanoscale.blogspot.com/2025/02/the-... NIH study sections paused www.thetransmitter.org/funding/fede... biomed grad school amissions paused www.statnews.com/2025/02/19/t...

No! Only study sections already announced in the federal register have resumed. Nothing has been posted by the NIH to the federal register since Jan 21. I am finding it wild how many professors don't know this. Please spread this info to your Universities!