Cenk Celik
@cenkcelik.bsky.social
Research Fellow @ugiatucl.bsky.social • Single-cell and spatial transcriptomics • EACR Ambassador https://cenk-celik.github.io
Evans et al. @barrallab.bsky.social identify CD1d as a key regulator of myeloid cell diversity in #BreastCancer. CD1d targeting reshapes tumor immune infiltrates, suppresses tumor growth, & enhances #immunotherapy efficacy, suggesting an actionable pathway for treatment. rupress.org/jem/article/...
Through a fantastic collaboration with @mariasecrier.bsky.social we show how dormant breast cancer cells occupy protected niches, presenting a therapeutic challenge. Congratulations to @cenkcelik.bsky.social for a super study
MRC Laboratory of Medical Sciences@mrc-lms.bsky.social · 3w agoA new study maps where dormant cancer cells hide in breast tumours: tucked into neighbourhoods of immune + support cells that may shield them from treatment. Understanding these hideouts could lead to new drug targets🧬 @mrc-lms.bsky.social @imperialmed.bsky.social @ucl.ac.uk
Yapay zeka teknolojilerinin toplumsal yaşamın her alanında yarattığı dönüşümler, ona bütüncül bir perspektifle yaklaşmayı zorunlu kılıyor. Bu etkinlik böyle bir perspektifi kurmanın yollarını aramak üzere tasarlandı. Kayıtlar devam ediyor: bilimler.org #bilimlerköyü #villageofsciences #yapayzeka
Congratulations to UCL’s Dr Gemma Murray on receiving a prestigious Wellcome Career Development Award, recognising her pioneering research into bacterial evolution and antimicrobial resistance. @ugiatucl.bsky.social www.ucl.ac.uk/life-science...
Gemma Murray awarded prestigious Wellcome Career Development Award
Dr Gemma Murray has been awarded a Wellcome Career Development Award to lead pioneering research into the hidden role of commensal bacteria in antimicrobial resistance (AMR).
ucl.ac.uk
Real treat to have @cenkcelik.bsky.social from @mariasecrier.bsky.social give #CEV talk "2 systems:1 Biology". Transferable concepts from #WoundHealing➡️ #CancerTransformation @qmbci.bsky.social @mcclellandlab.bsky.social @ciccarellilab.bsky.social @mirjana-efremova.bsky.social @mlockley.bsky.social
Are you interested in learning multiomics analysis for your project? Join me for a hands-on workshop at Bilimler Köyü (Village of Sciences) in Foça, İzmir for a week. #spatialtranscriptomics #scrnaseq
G0 or no-G0, if you’re interested in learning the role of phosphatases in regulating quiescence and cell cycle entry read this new review by Robinson & Barr published in #BiochemSocTrans https://doi.org/10.1042/BST20250091 🧪
10–16 Ağustos’ta Cenk Çelik hocamızın yürütücülüğünde gerçekleşecek olan bu etkinlikte; biyolojide tek hücreden uzamsal ölçeklerdeki yaşamın derinliklerine uzanan bir hattı, bilimsel verilerle iç içe tartışıyoruz. Merkezi dogma ve veri işlemeden gen düzenleyici ağlara; hücreler+
Lactic acid lover? Check out @ronni.bsky.social 's new work in @cp-cellhostmicrobe.bsky.social showing how Enterococcus faecalis-derived LA suppresses macrophage activation, in turn promoting bacterial persistence and polymicrobial wound infection in vivo. www.sciencedirect.com/science/arti...
Enterococcus faecalis-derived lactic acid suppresses macrophage activation to facilitate persistent and polymicrobial wound infections
Macrophage activation is essential for innate immunity and antimicrobial defense. We show that Enterococcus faecalis suppresses macrophage activation …
sciencedirect.com
We are also recruiting a Postdoc in cell/molecular biology! 3yr, fully funded by @cancerresearchuk.org more details here: news.cancerresearchuk.org/2025/11/27/s... Apply here: www.imperial.ac.uk/jobs/search-...
Spin doctors: taking on the challenge of tissue-specific cell cycle control - Cancer Research UK - Cancer News
A false start, a Nobel Prize and renewed hope – understanding cell cycle disruption over different tissues is complex. But we are getting there…
news.cancerresearchuk.org
Alexis Barr@alexisbarr.bsky.social · 7mo agoWe are recruiting a Postdoc in computational biology, together with @mariasecrier.bsky.social 4yr, fully funded by @cancerresearchuk.org, ideal for Postdocs wanting to develop their independence Applications open now: www.imperial.ac.uk/jobs/search-...
See UGI's Dr Marina Escalera Zamudio (Rosetrees Fellow) and Dr Cenk Celik (Research Fellow) @cenkcelik.bsky.social presenting at the Norwich Science Festival @niscifest.bsky.social session on "Reimagining Health with Big Data". norwichsciencefestival.co.uk/whats-on/rei... #NISF26
Reimagining Health with Big Data | Norwich Science Festival
Dr Marina Escalera Zamudio and Dr Cenk Celik will share the ways in which big data and AI are transforming medicine.
norwichsciencefestival.co.uk
Proud of this international effort led by NTU Singapore, @scelse.bsky.social and the University of Geneva. Huge props to first author @aarontan.bsky.social and my co-lead @kimingeneva.bsky.social and other authors including @cenkcelik.bsky.social. #ScienceAdvances #Microbiology #NTUsg
Have you ever heard that women have more chances than men of getting grants or positions in academia? Of course you have, and here are my personal views on this. With the shocking revelation that no, it is NOT TRUE ! (1/n)
There's still a few days left to apply for our AI-Intervene PhD project mapping the drivers of avian influenza using viral genomics, bird migration data and AI-powered phylodynamics. Come join us! Details below. #FindaPhD #LondonPhD #genomics
Lucy van Dorp@lucyvandorp.bsky.social · 9mo agoWe’re recruiting a PhD student as part of the AI-Intervene DTP to join FlightPath, an exciting project combining viral genomics, bird migration data, and AI-powered phylodynamics to forecast how avian influenza evolves and spreads. Project Details 🦠🧬🦅🦆🌎: tinyurl.com/2v4xaxmx.
Great talk from @ugiatucl.bsky.social post-doc @cenkcelik.bsky.social presenting his work developing new approaches to explore the spatial patterns of cancer evolution. Preprint 👉 www.biorxiv.org/content/10.1... Thanks for giving our last seminar of the year!
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How do tissues organise, adapt, or collapse? 🧬 We’re looking for a postdoc with strong quantitative skills to tackle these questions in a highly interdisciplinary project bridging spatial omics, ecology & mathematical modelling (expertise required in at least one topic). Apply 👉 tinyurl.com/3d37d3st
UCL – University College London
UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).
ucl.ac.uk
Come do some cool cell cycle science with the awesome @alexisbarr.bsky.social and me! 🔬✨ We’re looking for an enthusiastic computational biologist / data scientist (4-year postdoc) to dive into loads of cancer genomics & transcriptomics data. Details below. Please share!
Description
Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities ment...
imperial.ac.uk
Alexis Barr@alexisbarr.bsky.social · 11mo ago@mariasecrier.bsky.social & I are looking for an enthusiastic & excellent data scientist for a 4-year postdoc to understand cell cycle dysregulation in cancer. Deadline 15th October. Get in touch if you have any questions. Please repost! More details: www.imperial.ac.uk/jobs/search-...
@mariasecrier.bsky.social & I are looking for an enthusiastic & excellent data scientist for a 4-year postdoc to understand cell cycle dysregulation in cancer. Deadline 15th October. Get in touch if you have any questions. Please repost! More details: www.imperial.ac.uk/jobs/search-...
Description
Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities ment...
imperial.ac.uk
Feeling very fortunate to be awarded a Programme Foundation Award from CRUK @cruk-si.bsky.social This is a new area for the lab & lets us team up with @mariasecrier.bsky.social to tackle a big problem of how different cancers lose control of proliferation
MRC Laboratory of Medical Sciences@mrc-lms.bsky.social · 12mo agoCongratulations to @alexisbarr.bsky.social and Jesus Gil who have received funding awards, together totalling around £3M, from @cancerresearchuk.org! They will lead two exciting projects that could result in discoveries that make a real difference to the lives of people with cancer in the future.
Bu hafta “Yapay Zekanın Politik Ekonomisi” etkinliğinde Altuğ Yalçıntaş hocamız “büyük veri” meselesini iktisadi ve siyasal boyutlarıyla ele alırken, aynı saatlerde Cenk Çelik hocamız Tek Hücre ve Uzamsal Boyutta Canlılık” atölyesinde “hücreler arası iletişim konusunu masaya yatırıyordu.
We recently published a review reflecting on challenges and opportunities in characterising cancer cell states and niches using spatial transcriptomics and integration with digital pathology, see full thread below. Thank you Molecular Oncology for the opportunity!
Cenk Celik@cenkcelik.bsky.social · last yr.We, Secrier Lab UCL @ugiatucl.bsky.social Genetics Institute, discussed challenges in cell state identification using spatial transcriptomics in cancer research, now out in Molecular Oncology. doi.org/10.1002/1878... #SpatialTranscriptomics #CancerResearch #SpatialNiches
📢 Our new preprint is out! We show how the common gut bacterium 𝘌. 𝘧𝘢𝘦𝘤𝘢𝘭𝘪𝘴 stops wound healing. It uses a metabolic pathway, extracellular electron transport (EET), to stress host cells, halting their migration. Watch WT bacteria (orange) stop the cells while the mutant (blue) doesn't!
Bilimler Köyü'nde gelecek hafta... 📍 Detaylı bilgi ve başvuru: bilimler.org/etkinlikler/ #bilimlerköyü #villageofsciences
We, Secrier Lab UCL @ugiatucl.bsky.social Genetics Institute, discussed challenges in cell state identification using spatial transcriptomics in cancer research, now out in Molecular Oncology. doi.org/10.1002/1878... #SpatialTranscriptomics #CancerResearch #SpatialNiches
doi.org
New preprint from the Secrier lab. @cenkcelik.bsky.social @mariasecrier.bsky.social present EnrichMap, a Python package to compute gene set enrichment scores in spatial transcriptomics data: tinyurl.com/yc48f4fx. See an explainer thread from @cenkcelik.bsky.social here: bsky.app/profile/cenk....
EnrichMap: Spatially informed enrichment analysis for functional interpretation of spatial transcriptomics
Advances in spatial transcriptomics (ST) allow high-resolution mapping of gene expression within intact tissues, revealing spatially regulated biology. However, accurately quantifying gene set activit...
biorxiv.org
Cenk Celik@cenkcelik.bsky.social · last yr.[Preprint alert] We’re thrilled to introduce EnrichMap: a powerful new method for spatial gene set enrichment. It’s spatially aware, biologically meaningful and built for the next generation of spatial transcriptomics. www.biorxiv.org/content/10.1...
Want to uncover biologically meaningful patterns in spatial omics data? Check out our new method EnrichMap, details below. Work led by the brilliant @cenkcelik.bsky.social! #spatialomics #genesets
Cenk Celik@cenkcelik.bsky.social · last yr.[Preprint alert] We’re thrilled to introduce EnrichMap: a powerful new method for spatial gene set enrichment. It’s spatially aware, biologically meaningful and built for the next generation of spatial transcriptomics. www.biorxiv.org/content/10.1...
[Preprint alert] We’re thrilled to introduce EnrichMap: a powerful new method for spatial gene set enrichment. It’s spatially aware, biologically meaningful and built for the next generation of spatial transcriptomics. www.biorxiv.org/content/10.1...
Işık yalnızca çevremizi aydınlatmaz; aynı zamanda doğanın en temel sırlarını da içinde taşır. Bu etkinlikte, Cambridge Üniversitesi’nden Prof. Mete Atatüre ve Dr. Yusuf Karlı’nın yürütücülüğünde, ışığın klasik fiziğin ötesine geçen dünyasına adım atacağız. ++
