centrix

@centrixsystems.bsky.social

S3Mirror is an open source application for transferring large genomic datasets b/t S3 buckets efficiently, reliably, & with full observability. Built on DBOS Transact, it was created to meet the needs of a pharmaceutical organization handling clinical trial data. www.biorxiv.org/content/10.1...

S3Mirror: Making Genomic Data Transfers Fast, Reliable, and Observable with DBOS

To meet the needs of a large pharmaceutical organization, we set out to create S3Mirror - an application for transferring large genomic sequencing datasets between S3 buckets quickly, reliably, and ob...

biorxiv.org

I think "context engineering" is going to stick - unlike "prompt engineering" it has an inferred definition that's much closer to the intended meaning, which is to carefully and skillfully construct the right context to get great results from LLMs simonwillison.net/2025/Jun/27/...

Context engineering

The term context engineering has recently started to gain traction as a better alternative to prompt engineering. I like it. I think this one may have sticking power. Here's an …

simonwillison.net

Announcing Datasette for Newsrooms - a hosted version of @datasette.io specifically targeted at newsrooms and data journalists Think of it as a library for your data - load in CSVs and JSON, extract data with LLMs, collaborate on analysis with the rest of your team simonwillison.net/2025/Apr/24/...

Introducing Datasette for Newsrooms

We're introducing a new product suite today called **Datasette for Newsroows** - a bundled collection of Datasette Cloud features built specifically for investigative journalists and data teams. We're...

simonwillison.net

Ever wanted to build a custom embedded device but felt stuck with off-the-shelf boards? Meet Trellis! 🌱 A Nerves-first, open-source hardware platform that gives you a solid starting point for your custom hardware projects I'm beyond excited to speak about it at @elixirconf.bsky.social EU in May!

A graphic with a rendering of a custom single board computer with the form factor of a Raspberry Pi, but with different connectors. The text says "Coming soon to a GitHub repo near you"

Running DBOS at scale just got way easier. Introducing Conductor, a managed service that helps you operate self-hosted @dbos.dev applications in production across your infrastructure or any cloud. Imagine distributed workflow recovery, observability, and queue management. 🧵

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The most common request we've heard from users has been better support for self-hosting DBOS at scale. We're excited to introduce 𝐂𝐨𝐧𝐝𝐮𝐜𝐭𝐨𝐫, a managed service for operating self-hosted apps in production. What sets DBOS apart is that Conductor runs out of band with no access to your private data. 🧵

Durable Execution Anywhere - Introducing DBOS Conductor | DBOS

Announcing DBOS Conductor. a managed service that helps you operate self-hosted DBOS Transact applications in production, on your own infrastructure or in any cloud.

dbos.dev

🥳Latest free eBook is a deep dive on @cilium.io network policy engine available now!🔥 > Label-Based Security Identities > Multi-Tenancy & Policy Scoping > Real-World Policy Implementations > Scaling and Observability > Advanced Security Strategies isovalent.com/blog/post/ci... #Kubernetes #ebpf

Understanding Kubernetes Network Security: Cilium Network Policy Deep Dive eBook - Isovalent

Explore our comprehensive eBook for an in-depth understanding of Cilium's network policy engine and its advanced capabilities

isovalent.com