We are offering a fully funded two-year postdoctoral position focused on sex chromosome evolution and speciation in the *Jaera albifrons* species complex. Please find the advertisement attached. We welcome applications from interested candidates. Join us :-)

Hybridization and introgression are major evolutionary processes. Since the 1940s, the prevailing view has been that they shape plants far more than animals. In our new study (www.science.org/doi/10.1126/... ), we find the opposite: animals exchange genes more, and for longer, than plants

Really excited to see this work, led by Mike Grundler, published! It's a new method for inferring the geographic locations of shared genetic ancestors. In the paper, we and use it to infer the geographic history of human genetic ancestry www.science.org/doi/10.1126/...

A geographic history of human genetic ancestry

Describing the distribution of genetic variation across individuals is a fundamental goal of population genetics. We present a method that capitalizes on the rich genealogical information encoded in g...

science.org

🚨Urgent: 12-month Postdoc in Paris-Saclay on the INCREASE project! 🫘 Dissecting genetic mechanisms of environmental adaptation in common bean Project: [https://www.pulsesincrease.eu/] 📄 Click on Job for description [https://moulon.inrae.fr/] Please share! #Postdoc #JobOpening #INCREASEProject

Excited to share our latest preprint evaluating AlphaFold3, Boltz-1, Chai-1 and Protenix for predicting protein-ligand interactions, featuring our newly introduced benchmark dataset 🌹Runs N’ Poses🌹! www.biorxiv.org/content/10.1... 🧵👇 (1/n)

Have protein-ligand co-folding methods moved beyond memorisation?

Deep learning has driven major breakthroughs in protein structure prediction, however the next critical advance is accurately predicting how proteins interact with other molecules, especially small mo...

biorxiv.org

New paper with Sarthak Mishra! Maybe it will bring you some joy given all this (waves arms around). "Estimating recombination using only the allele frequency spectrum" 1/2 www.biorxiv.org/content/10.1...

Estimating recombination using only the allele frequency spectrum

Standard methods for estimating the population recombination parameter, rho, are dependent on sampling individual genotypes and calculating various types of disequilibria. However, recent machine lear...

biorxiv.org

Genome architecture and speciation in plants and animals. I learned a lot writing this with @dortizba.bsky.social, Silu Wang and Loren Rieseberg! doi.org/10.22541/au....

Octo-squid-nautiloid sex chromosomes! www.sciencedirect.com/science/arti...

Cephalopod sex determination and its ancient evolutionary origin

Octopuses, squids, and cuttlefishes—the coleoid cephalopods—are a remarkable branch in the tree of life whose members exhibit a repertoire of sophisti…

sciencedirect.com

Join us on Wednesday, February 5, at 11 AM PST for the next #PolyploidyWebinar! This month we have @cherrityg.bsky.social on apomixis and polyploidy in Malus and Christoph Rosche on herbarium specimens and invasive Centaurea! Sign up (if not already!) to get the zoom: www.barkerlab.net/polyweb

📣 The final chapter of my PhD is now out in @evolletters.bsky.social !! 📣 🦌 Using genomic and fitness data from a long-term study of red deer we investigated the interaction between inbreeding depression and the environment (ID × E) doi.org/10.1093/evle...

Fine-scale spatial variation in fitness, inbreeding, and inbreeding depression in a wild ungulate

Abstract. Environmental stress can exacerbate inbreeding depression by amplifying differences between inbred and outbred individuals. In wild populations,

doi.org

Do you think marine evolution #MarEvol is cool? Maybe you were at the 2018 Marine Evolution meeting in Strömstad, Sweden? And surely you'd like us to do it again and organise MarEvol2? Why not in the South of France? Then fill in this questionnaire and spread the word: framaforms.org/my-interest-...

The maintenance of genetic polymorphism underlying sexually antagonistic traits doi.org/10.1093/evle... Now in @evolletters.bsky.social by Ewan Flintham et al.

The maintenance of genetic polymorphism underlying sexually antagonistic traits

Abstract. Selection often favors different trait values in males and females, leading to genetic conflicts between the sexes when traits have a shared gene

doi.org

Check out our exciting programme of early-career speciation research talks for the Gordon Research Symposium on Speciation, this March in Ventura www.grc.org/speciation-g... Graduate students & postdocs, if you'd still like to join us: make sure to register before the 1st of Feb!

Do mutations that drive evolution improve many traits or few? Does this change over the course of evolution? Excited to share our work in PLOS Biology exploring these questions in the first 2 adaptive steps w/ Yuping Li, @gsherloc.bsky.social, @petrovadmitri.bsky.social 🧵 doi.org/10.1371/jour...

A high-resolution two-step evolution experiment in yeast reveals a shift from pleiotropic to modular adaptation

Evolution is expected to involve mutations that are small and modular in effect, but recent findings suggest that mutations early in an adaptive process can have strong and pleiotropic effects. This s...

doi.org

In 2010 (SMBE Lyon) I gave a talk about the impact of GC-biased gene conversion (gBGC) on functional sequence evolution. I argued that, because gBGC promotes G and C alleles irrespective of their fitness effect, it should generate some genetic load. 1/5