What if you could record cytosolic activities or archive proteins on an intracellular tape across time? 📼 Introducing: 🔍 CytoSense records protease & kinase signaling activities 📦 CytoCatch archives cytosolic proteins along CytoTape Preprint: doi.org/10.64898/202... 🧵Thread (1/7)
Changyang Linghu
@changyanglinghu.bsky.social
Assistant Professor at UMich, PhD at MIT, NIH Director's New Innovator Awardee, MIT Technology Review's Innovator Under 35, www.spatialbiodynamics.org
Introducing GLOBE—a new technology for brain-wide, single-cell recording of cellular activity in vivo. GLOBE can continuously record from nearly a quarter million individual neurons simultaneously across a mouse brain. Preprint out on bioRxiv: doi.org/10.64898/202... 🧵(1/6)
Our CytoTape work is published today in Nature @nature.com! CytoTape is a genetically encoded, flexible, intracellular protein tape recorder for spatiotemporally scalable and multiplexed recording of cellular activities continuously across weeks in vitro and in vivo. www.nature.com/articles/s41...