Constipation Prevalence and Its Association With Kidney Function: A Large Nationwide Japanese Health Check-Up Cohort Study

AbstractBackground. Constipation is one of the most common gastrointestinal disorders in the general population. However, its prevalence in patients with c

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SGLT2 inhibitors and bone health in CKD

Chronic kidney disease (CKD) poses a major threat to global health. With a prevalence of >10%, CKD is estimated to be among the leading causes of premat

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Beyond expensive innovations: affordable and effective strategies for managing tubulopathies in adults

ABSTRACT. Tubulopathies comprise a heterogeneous and still poorly defined group of inherited and acquired disorders in which tubular transport is dispropor

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Volume 19 Issue 3 | Clinical Kidney Journal | Oxford Academic

The official open access journal of the European Renal Association - European Dialysis Transplant Association. It is an essential educational and training resource integrating clinical, translational,...

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A case of adrenal insufficiency after initiation of targeted release budesonide formulation (Nefecon) in a Patient with IgA nephropathy

Abstract. We describe a case of IgA nephropathy (IgAN) treated with targeted-release budesonide (Nefecon) that resulted in notable systemic adverse effects

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Turning major revision into opportunity: ten tips to navigate peer review after manuscript submission

Mythri Shankar, Mohamed Hassanein, Alexander Woywodt; Turning major revision into opportunity: ten tips to navigate peer review after manuscript submission

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Use of acetazolamide in volume overload: start at the beginning

ABSTRACT. The treatment of volume overload has vexed physicians for centuries. References to herbal remedies for the treatment of fluid retention date as f

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Role of lupus nephritis classification systems in everyday clinical practice: a questionnaire-based survey of the Renal Pathology Society (RPS)

AbstractBackground. Kidney biopsy is the gold standard for lupus nephritis (LN) diagnosis, with the 2018 International Society of Nephrology/Renal Patholog

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Targeting B cells in IgA nephropathy: from pathogenic insight to therapeutic horizon

ABSTRACT. Immunoglobulin A nephropathy (IgAN) remains the most common primary glomerulonephritis globally. Advances in mucosal immunology have illuminated

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Mechanism of reduced intestinal phosphate absorption by tenapanor: a hypothesis

ABSTRACT. Tenapanor, a selective inhibitor of the sodium/hydrogen exchanger isoform 3 (NHE3), was initially developed for the treatment of irritable bowel

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Improving precision diagnosis in unexplained CKD

Comment on Halbritter et al. „Chronic Kidney Disease of unexplained cause (CKDx): a consensus statement by the Genes & Kidney Working Group of the ERA

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Transformative Global Models for CKD Care: Case Studies and Strategies

Abstract. Chronic kidney disease (CKD) affects approximately 10% of adults worldwide and is associated with an elevated risk of cardiovascular disease, suc

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Microscopic hematuria in IgA nephropathy: a biomarker of disease activity

Abstract. Immunoglobulin A nephropathy (IgAN) is an immune-mediated disease of B-cell origin and the most common primary glomerulonephritis worldwide, whic

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Protocadherin FAT1-associated membranous nephropathy after hematopoietic stem cell transplantation – a cohort study with clinico-pathological correlations

AbstractBackground. The identification of causative antigens for membranous nephropathy (MN) has revolutionized the comprehension of the pathophysiology of

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Impact of dapagliflozin on Bone Mineral Metabolism in Non-diabetic patients with chronic kidney disease: a randomized, double-blind, placebo-controlled study

AbstractBackground. SGLT2i have demonstrated reno-protective effects in patients with CKD. However, concerns remain regarding their potential effect on bon

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Sex disparities in mortality and cardiovascular outcomes in chronic kidney disease

ABSTRACT. Sex (biologically determined) and gender (socially constructed) modulate manifestations and prognosis of a vast number of diseases, including car

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Making Use of Avacopan in Clinical Practice

Abstract. Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a severe multisystem autoimmune disease in which renal involvement is c

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Antidepressant prescriptions by provider in patients with kidney failure and depression

AbstractBackground. The prevalence of depression is high among patients with end-stage kidney disease (ESKD). Recent studies have indicated under-recogniti

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Uremic Frost: A Historical Note

Søren H Elsborg, Rikke Nørregaard, Henricus A M Mutsaers; Uremic Frost: A Historical Note, Clinical Kidney Journal, , sfaf368, https://doi.org/10.1093/ckj/

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Ten tips on how to manage obesity in the presence of CKD

ABSTRACT. Patients with chronic kidney disease are frequently facing the challenge of weight reduction. Finding a weight loss strategy is on the one hand e

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Ten tips to manage oral anticoagulation in hemodialysis patients with atrial fibrillation

ABSTRACT. Patients with chronic kidney disease (CKD) have a high incidence and prevalence of atrial fibrillation (AF). While general treatment strategies f

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Clinical and genetic features of Gitelman syndrome patients with hyperuricemia

ABSTRACTBackground. Gitelman syndrome (GS) is a rare inherited salt-losing tubulopathy caused by dysfunction of the thiazide-sensitive sodium-chloride cotr

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Cardiac Impact of Dapagliflozin in Advanced Chronic Kidney Disease: Rationale and Design of the Renal Lifecycle Trial Cardiac Imaging Sub-studies

AbstractBackground. Patients with chronic kidney disease (CKD) are frequently hospitalized for heart failure. Sodium glucose co-transporter 2 (SGLT2)-inhib

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