Check out the latest paper from the lab! We have shown how sensory neurons inhibit immune responses in the context of lung cancer. www.cell.com/cell/fulltex...
Nociceptive innervation limits tertiary lymphoid structures to promote lung cancer
Nociceptive sensory neurons are engaged during lung adenocarcinoma tumorigenesis, suppressing tertiary lymphoid structure formation and blunting anti-tumor immunity. This study reveals CGRP signaling ...
cell.com
Researchers at the Crick have uncovered how lung tumours can hijack the activity of nearby nerves to weaken the body’s immune response. This research was led by Ya-Hsuan Ho and Giacomo Bregni, with corresponding author Leanne Li. www.crick.ac.uk/news/2026-05...