@bsky.app New preprint: "A personalized map of where, when, and how to stimulate the brain to elicit controlled responses." biorxiv.org/content/10.6... We use personalized AI surrogate brains to predict where, when & how to stimulate for reliable effects. Thread 👇 www.linkedin.com/posts/grabuf...

A personalized map of where, when, and how to stimulate the brain to elicit controlled responses

Brain stimulation has transformed the treatment of several neurological and psychiatric disorders and is now widely used to read out causal interactions in the human brain. However, its effects vary f...

biorxiv.org

Keep reading more and more about the potentiality of brain stimulation. Can't wait to see where this other piece of the puzzle will bring our understanding 🦾 ...and what a great player put it in the right spot 🌺

Giovanni Rabuffo@grabuffo.bsky.social · 11mo ago

🧠⚡️Brain stimulation is powerful, yet its effects are notoriously variable: identical parameters can produce very different outcomes. In our new preprint, we show how the brain’s state before stimulation helps explain and reduce this variability. 🧵1/n doi.org/10.1101/2025...

🧠⚡️Brain stimulation is powerful, yet its effects are notoriously variable: identical parameters can produce very different outcomes. In our new preprint, we show how the brain’s state before stimulation helps explain and reduce this variability. 🧵1/n doi.org/10.1101/2025...

Pre-stimulus Brain States Predict and Control Variability in Stimulation Responses

Does the ongoing brain state determine how it responds to localized electrical stimulation? This fundamental question has major implications for neuroscience and medicine, as stimulation outcomes rema...

doi.org

After a long journey, our paper is officially out in PNAS! 🚀 Huge thanks to the team — excited to finally share it with the world. Check it out: www.pnas.org/doi/10.1073/...

Mapping global brain reconfigurations following local targeted manipulations | PNAS

Understanding how localized brain interventions influence whole-brain dynamics is essential for deciphering neural function and designing therapeut...

pnas.org

Good things come in a bunch! Not only is my paper getting great recognition, but I have also submitted my PhD thesis and received a research grant from the Canon Foundation in Europe to spend the next few months working on my next project at the Okinawa Institute of Science and Technology! 🇯🇵

Our paper is out! We used Micro-C to study the 3D genome organization at high resolution in trypanosomes and revealed an extensive network of inter-chromosomal transcription hubs. read more at doi.org/10.1038/s414... 🧬 Great work from @claudiarabu.bsky.social @naturecomms.bsky.social

Looking for a nice read over the holidays? Check out my paper, out now in @naturecomms.bsky.social! Using Micro-C in trypanosomes, we found an extensive network of interactions between polymerase-class specific loci. doi.org/10.1038/s414... 🧬

Inter-chromosomal transcription hubs shape the 3D genome architecture of African trypanosomes - Nature Communications

Decoding the role of inter-chromosomal DNA-DNA interactions remains challenging. Here, the authors use Micro-C to study the T. brucei genome architecture at high resolution and reveal an intricate net...

doi.org