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What are the risks associated with bipolar disorder in the perinatal period? How can these risks be managed during pregnancy and lactation? What monitoring is required for a pregnant person taking mood stabilizers? Find out in our latest decisions article ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.251879

Pregnancies in patients with bipolar disorder are at a higher risk of obstetric and fetal complications than unaffected pregnancies.

"Health care system leaders must not use individuals as convenient human shields to avoid taking accountability for a complex system problem." How to stop Canada’s emergency physicians from leaving their profession: an editorial by Dr. Catherine Varner ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.261030

Emergency physician attrition will continue until emergency department overcrowding is mitigated. Given the multifaceted problem that this overcrowding poses, solving it will require substantial investment in acute care and long-term care capacity.

Combined therapy versus monotherapy in type 2 diabetes: Assessing cardiovascular and kidney outcomes of combined SGLT2i and GLP-1RA therapy versus monotherapy in the management of type 2 diabetes mellitus using network meta-analysis. Learn more ➡️ www.cmaj.ca/lookup/doi/10.1503/cmaj.250369

Compared with SGLT2 inhibitors or GLP-1 receptor agonists alone, combined therapy did not significantly reduce the risk of major adverse cardiovascular or kidney events but was associated with lower risks of hospitalized heart failure.

Combined therapy versus monotherapy in type 2 diabetes
DOI: 10.1503/cmaj.250369

🩺🔍 Pulmonary embolism: what is the latest on management? Read new articles on management of pulmonary embolism; anaplasmosis and myocarditis; combined therapy versus monotherapy in type 2 diabetes; and more, published in this week's issue of CMAJ. ➡️ https://www.cmaj.ca/content/198/26

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🎉 CMAJ Podcasts just hit ONE MILLION downloads! Thank you to everyone who has listened, shared, and supported the show. People truly value trusted health information — accurate, evidence‑based conversations matter more than ever. Listen + subscribe: CMAJ.ca ➡️ www.cmaj.ca/page/multime...

🩺🔍 Otitis externa: what’s the latest on diagnosis and management? Read new articles on otitis externa; fatal rabies in a child; adverse effects from sedatives in older adults; and more, published in this week's issue of CMAJ. ➡️ https://www.cmaj.ca/content/198/25

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