The Big Long COVID Neuroplasticity Trial: Did it Work? - Health Rising

A large neuroplasticity long COVID trial appears to noticeably improve a small subset of patients, and has small to modest effects on most others.

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The UK's Long COVID Triple Treatment Trial (Not Surprisingly) Bombs - Health Rising

A large UK Long COVID treatment trial that assessed 3 drugs/drug combos utterly failed. It's not alone - none of the 14 or so largish long COVID trials have produced good results. Perhaps it's not a s...

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Stepping Backwards - the U.S.'s Attempt to Politicize Scientific Research: An Editorial - Health Rising

Health Update –  continued slow improvement! Hot Button Post – the reason Health Rising almost never posts on political issues is that they hardly ever intrude upon medical research. In this case, the...

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Visible At Last? Are Long COVID and ME/CFS Tissue Diseases? The PolyBio 2026 Symposium Pt I - Health Rising

Geoff’s Narration The GIST   The 2026 PolyBio Spring Symposium – Pt I One way to gauge the health of a field is by the number of conferences/symposia it supports. From the looks of things, the long–CO...

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Hitting the Target? ME/CFS and long COVID T-Cell Researchers on Uncovering the Precise Drivers of the Illnesses - Health Rising

Dr. Selin and company believe they can solve one of the key mysteries of ME/CFS and long COVID: exactly why the T-cells are getting pummeled.

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Major Study Validates a Long COVID Autoimmune Subset - Health Rising

A major study determines that autoimmunity is causing major symptoms in long COVID ultimately laying the groundwork for precision-guided treatments

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Sticky Nets and Damaged Blood Vessels: A Long COVID Subset is Born? - Health Rising

A long COVID study uncovers a subset of patients with microclots and signs of blood vessel damage who, if the findings are validated, might benefit from rarely used treatments.

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A Novel Immunomodulatory Strategy for ME/CFS + A Paradox Resolved? - Health Rising

A novel immunomodulatory treatment approach to ME/CFS appears and a paradox could be resolved....

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Takeaways From the Big Long COVID Clinical Trials - Health Rising

Only 10 major long COVID clinical trials have been published thus far but that's enough to come away with some interesting takeaways. They include treatments that prevent long COVID don't necessarily ...

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Are All Roads Leading to the Immune System and the Blood in ME/CFS? - Health Rising

What happens when you throw ten or so very different ME/CFS studies together? You get some core themes popping out. Check out the blog and see what they are.

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"Invisible No More": Exploring Dr. Ruhoy's New Treatment Guide for ME/CFS, Long COVID, etc. - Health Rising

An in-depth exploration of Dr. Ruhoy's treatment guide "Invisible No More" for ME/CFS, long COVID and similar diseases

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The Massive Sequence ME/CFS and Long COVID Project Aims to Find Precision Drivers of These Illnesses - Health Rising

The massive Sequence ME/CFS and long COVID whole genome sequencing project aims to find the precision drivers of these illnesses

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Psilocybin Passes First Tests: Improves Symptoms in Fibromyalgia and Post Treatment Lyme Disease - Health Rising

Geoff’s Narration The GIST   “These substances represent a potentially revolutionary approach to pharmacological pain management,” Crozpek et. Al. 2025 History has shown that our notions of what treat...

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Blood, Sex and Inflammation: Did the IMPACC Study Uncover Core Issues in Long COVID and ME/CFS? - Health Rising

The big IMPACC long COVID study findings suggest that inflammation and reduced male sex hormone levels may be playing havoc with the small blood vessels in long COVID -= and ME/CFS

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Is the OMF's ME/CFS BioQuest Study the Study We've All Been Waiting For? - Health Rising

The Open Medicine Foundation's huge Bioquest project has the potential to transform ME/CFS patients experience with doctors, dramatically enhance research and get drug companies finally interested in ...

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Precision Medicine Required For ME/CFS? A Deep Genome Dive Uncovers Many Possible Causes - Health Rising

A deep dive into the genome of ME/CFS patients points to many genetic causes of ME/CFS most of which impact energy production, the metabolism, and blood flows.

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Tackling the World's Most Complex Diseases: Amatica's ME/CFS and Long COVID Project - Health Rising

Amatica's huge gene expression database attempts to identify which subsets a person belongs in and which treatments that may work for them.

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"Something in the Blood" Again! ME/CFS and Long COVID Serum Locks the Muscles Down - Health Rising

Geoff’s Narration The GIST Muscles on a Chip Whoa, another muscle study. We recently reported on a proteomic study suggesting that muscle repair problems contribute to post-exertional malaise in ME/CF...

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ME/CFS Autopsy Study Finds a Wrecked HPA Axis: The 2025 IACFS/ME Conference Report #3 - Health Rising

A Dutch ME/CFS autopsy report findings multiple severe problems in the HPA axis of ME/CFS patients.

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A Fibromyalgia Autoimmune Subset Rears Its Head - Health Rising

More evidence is presented that the most severely ill fibromyalgia patients have an autoimmune disease.

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A Long COVID Autoimmune Subset Coming into View? (and Why ME/CFS May be Next) - Health Rising

Solve ME Catalyst Award winner Dr. Iwasaki explains a subset of long COVID patients may have an autoimmune disease. Now she moves onto ME/CFS.

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The GLP-1 Agonist Boom in ME/CFS, FM and Long COVID: Insights, Using it, Trials Underway - Health Rising

Complex, chronic illness experts discuss what GLP-1 agonists can and can't do in diseases like ME/CFS, long COVID, and POTS. Plus new long COVID trials.

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The Brain Disease: Huge Fibromyalgia Genetic Study Highlights the Brain and Offers New Treatment Possibilities - Health Rising

Geoff’s Narration The GIST   Just months after the publication of the first large ME/CFS GWAS study comes an enormous FM GWAS study. Notice how these two diseases seem to be marching hand in hand. Bot...

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New Epigenetic Diagnostic Test For ME/CFS Wows ... But Can It Hold? - Health Rising

Geoff’s Translation The GIST   “With this breakthrough, we are proud to enable a first-in-class test that can address an unmet need for a quick and reliable diagnostic for a complex, challenging-to-id...

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RECOVER's 2nd Round of Long COVID Clinical Trials Shows Progress... and Limitations - Health Rising

The RECOVER Initiative announces four more clinical trials for long COVID including low dose naltrexone, bariticinib, GLP-1 agonists, and stellate ganglion blockade.

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In Good Health: How Chronic Illness Redefined My Relationship with Food - Health Rising

In Good Health cookbook by Rachel Riggs

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Is the Long COVID Field Missing a Major Opportunity? - Health Rising

Geoff’s Narration The GIST   From viral persistence to complex immune studies, to tissue sampling, to assessing heavy-duty immune treatment trials and large treatment trials, long-COVID researchers ar...

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The Promise of Vagus Nerve Stimulation - and the No Brainer Long COVID Trial Underway - Health Rising

Vagus nerve stimulation could reduce inflammation, pain and stress in ME/CFS, fibromyalgia and long COVID. A long COVID trial is underway.

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Gut Reactions: BioMapAI Points to Multiple Dysregulated Systems in ME/CFS - Health Rising

BioMapAI study suggests the gut problems in ME/CFS are driving other system malfunctions and symptoms.

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Surprise! The Senate Bill Includes "Some of the Strongest Support for ME/CFS in Years": Plus, Taking it to the House - Health Rising

The Senate Appropriations bill provides strong support for ME/CFS and long COVID. Now it moves to the House.

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