"Post-Transcriptional Regulation of Allele-Specific Expression" by Guan-Zheng Luo & colleagues "Emerging evidence reveals that the ‘allelic code’ is indeed propagated throughout the RNA life cycle..." FREE till Sept 18th at authors.elsevier.com/a/1nWtOcQbJI...

Next summer's Epigenetics GRC (I'm co-chairing with Deborah Bouch'is) is shaping up nicely with an all-star lineup of speakers working on a broad range of organisms and systems and everything from molecular mechanisms to new phenomena. Apply and put it on your calendar! www.grc.org/epigenetics-...

"B chromosomes put the 'super' in supernumerary" by Kaylah Samuelson & Stacey Hanlon "In the 21st century, extraordinary advances in sequencing technology and bioinformatics have transformed the field of B chromosome biology..." Read more here: authors.elsevier.com/sd/article/S...

"Olduvai Domains: Humanity’s Lucky Brake" by James M. Sikela "Our species has been given exceptional cognitive abilities... What fortunate genomic change made this possible?" FREE till Sept. 6th at: authors.elsevier.com/a/1nSfLcQbJI...

"A Blind Spot in lncRNA Discovery" by Hidenori Tani FREE till Sept. 5th at: authors.elsevier.com/a/1nSQLcQbJI...

"Transcription in check at DNA Double Strand Breaks" by Gaelle Legube & colleagues authors.elsevier.com/sd/article/S...

"Beyond Gene Expression: Single-Cell Transcriptomics at Isoform Resolution" by Lan Lin & colleagues authors.elsevier.com/sd/article/S...

"Coordinated pre-mRNA processing at the single transcript level" by Leena P. Sen & Karla M. Neugebauer FREE till Aug. 26th at authors.elsevier.com/a/1nOvLcQbJI...

"Reading another hidden message in the genetic code" by Yuichiro Mishima This Spotlight highlights a recent Science paper by Hia and colleagues in which they identified human DHX29 as a reader of an mRNA stability code. FREE till Aug. 25th at authors.elsevier.com/a/1nOYrcQbJI...

"Genetic suppressors as new therapeutic targets for Mendelian diseases" by Jolanda van Leeuwen & colleagues "Suppressor genes, which, when mutated, rescue the detrimental effects of a disease mutation, can encode promising alternative drug targets..." authors.elsevier.com/sd/article/S...

Genetic suppressors as new therapeutic targets for Mendelian diseases

Most Mendelian diseases lack effective treatments, with current options often limited to symptomatic care rather than addressing the underlying geneti…

authors.elsevier.com

The future of marsupial gene editing: what’s in the (tool) pouch? by Melanie K. Laird & colleagues "Genome editing in marsupials...has the potential to revolutionise the contribution of marsupial models to evo-devo and clinical research..." FREE till Aug. 22nd: authors.elsevier.com/a/1nNVLcQbJI...

📢 Call for Workshops: 2027 AGBT Agricultural Meeting Bring your community, advance discovery, and build collaborations that last. 📍Intercontinental Miami, Miami, Florida 📅 April 4–7, 2027 Submit your workshop proposal by August 27, 2026: hubs.ly/Q04n65F80 #AGBTAg27 #AgriculturalGenomics

"Beyond Housekeeping: snRNA Diversity, Regulation, and Human Disease" by Maciej Cieśla & colleagues FREE till Aug. 14th at authors.elsevier.com/a/1nKZvcQbJI...

"A role for epigenetics in rapid adaptation" by Reid S. Brennan & Melissa H. Pespeni "Epigenetic variation may be key to rapid adaptation and can interact with genetic change during evolutionary rescue. However, key questions remain.." FREE till Aug. 7th at authors.elsevier.com/a/1nH%7EscQb...

"The Myth of Asexual Fungi" by Felix Grewe & H. Thorsten Lumbsch "It was hypothesized that asexuality is common in fungi, but genomic research indicates there is actually a continuum of reduced, rare, or cryptic sexual activity..." FREE to read till Aug. 7th at authors.elsevier.com/a/1nI6McQbJI...

"Rethinking Mitochondrial Metabolism: Intra-Individual variability Meets Population Constraints" by José L. Cabrera-Alarcón & José A. Enríquez authors.elsevier.com/sd/article/S...

New paper out! With @amrojasm.bsky.social @bombarelya.bsky.social @svalver.bsky.social Ildefonso Cases, Scott Handley & yours truly @ibe-barcelona.bsky.social @cabd-upo-csic.bsky.social @ibmcp.bsky.social @csic.es

Trends in Genetics@cp-trendsgenetics.bsky.social · 2mo ago

"Rethinking molecular evolution through protein language model embeddings" by Rosa Fernández, Ana M. Rojas, & colleagues FREE till Aug. 4th at authors.elsevier.com/a/1nGxPcQbJI...

"Rethinking molecular evolution through protein language model embeddings" by Rosa Fernández, Ana M. Rojas, & colleagues FREE till Aug. 4th at authors.elsevier.com/a/1nGxPcQbJI...

"Co-transcriptional Splicing: Distinct Phases, Mutual Benefits, and Basis for Nuclear Architecture" by Xiang-Dong Fu & colleagues FREE till Aug. 2nd at authors.elsevier.com/a/1nGEOcQbJI...

"Viral tags as keys to advancing invasion genomics" by Senne Heeren & colleagues "We present a conceptual framework outlining how virus evolution may shed light on the contemporary spread of their non-native hosts..." FREE till July 31st at authors.elsevier.com/a/1nFgD_3rsx...

"The SMN locus in the T2T era: structure, gene conversion, and clinical implications" by Ewout Groen, Gijs van Haaften, & colleagues "[T]hese advances point toward a future in which structurally complex regions are no longer ‘dark’ areas of the genome..." authors.elsevier.com/sd/article/S...

"From mobile DNA to medicine: Fusion Conference highlights the therapeutic potential of endogenous retroelements in human disease" a TrendsTalk with conference chairs Katherine B. Chiappinelli, Hui Shen, Ting Wang, & Tao P. Wu authors.elsevier.com/a/1nFttcQbJI...

Very excited to share our new review on the complexity of SMA genetics, now online @cp-trendsgenetics.bsky.social! General interest in complex genetics? Want to know more about long-read sequencing? Segmental duplications? ✅✅✅ Have a look! www.cell.com/trends/genet...

The SMN locus in the T2T era: Structure, gene conversion, and clinical implications

Long-read sequencing, paralog-aware variant calling, and telomere-to-telomere (T2T) human genome assemblies now enable the resolution of copy-, haplotype-, and nucleotide-level complexities in segment...

cell.com

A more digestible explanation, that relates to this article, can be found here (in Dutch): www.eoswetenschap.eu/natuur-milie...

Super stoked to share that our Opinion article is now online at @cp-trendsgenetics.bsky.social!!! With "our" I mean: @teuneverts.bsky.social, @sdellicour.bsky.social and myself!! Here is a link to our piece: authors.elsevier.com/a/1nFgD_3rsx...

"The fungal RIP hypermutator mechanism has deep eukaryotic roots" by Thomas Badet & colleagues authors.elsevier.com/sd/article/S...

🧬 Unes regions del genoma humà considerades ADN brossa podrien tenir un paper clau en el càncer ⭐ "(...) es podrien obrir futures vies per explorar el seu paper de biomarcadors o de vulnerabilitats terapèutiques" 📑Art. Ref. ( @cp-trendsgenetics.bsky.social, abril de 2026): tinyurl.com/5n8cp59y 🔓

Identifying fate-determining transcription factors with single-cell omics by Xuegong Zhang (张学工) & co "In this article, we systematically review computational approaches for key TF identification and organize them from three perspectives..." FREE till Jul 24 at authors.elsevier.com/a/1nDJ1cQbJI...

Emergence of Protein Coding Enhancer RNAs in Primate Evolution by Ramin Shiekhattar & co "Recent work from Vlasov et al. shows that a subset of eRNAs contain ORFs translated into arginine-rich proteins with exquisite primate specificity..." FREE till July 25 at authors.elsevier.com/a/1nDXtcQbJI...

"Emerging role of G-quadruplexes in alternative splicing regulation" by Marc Blondel & colleagues "We present the increasingly emerging roles of rG4s in AS regulation and discuss the potential mechanisms behind these roles..." FREE till July 24th at authors.elsevier.com/a/1nDBMcQbJI...