Merci @xpolytechnique.bsky.social pour le coup de projecteur sur notre étude ! 🔬 Comment les ribosomes des archées hibernent-ils ? Réponse ici :
Comment les ribosomes des archées « hibernent » - École polytechnique, éco…
polytechnique.edu
Clément Madru
@cryoclem.bsky.social
Assistant Professor in structural biology (💎 & 🔬) Structural Biology of the Cell - BIOC École polytechnique - Institut Polytechnique de Paris - Palaiseau -France.
Merci @xpolytechnique.bsky.social pour le coup de projecteur sur notre étude ! 🔬 Comment les ribosomes des archées hibernent-ils ? Réponse ici :
Comment les ribosomes des archées « hibernent » - École polytechnique, éco…
polytechnique.edu
Happy to share our latest paper: www.nature.com/articles/s41... Great collaboration with @ifremer.bsky.social, @cbitoulouse.bsky.social & @pasteur.fr. Studying stress in P. abyssi with near-native, minimally purified ribosomes, we identified HibA, a new hibernation factor widespread in Archaea.
Sharing this figure from the Koonin lab: www.nature.com/articles/s41... Worth printing large and framing
Our work on ribosome hibernation in archaea is out! We identified Hib, a new hibernation factor broadly distributed across archaea. Check out the preprint 👉 biorxiv.org/content/10.1101/2025.10.11.676729v1 (1/🧵)
First ribosome purification using poly-lysine beads (RAPPL, developed by @djuranoviclab.bsky.social & collaborators: www.biorxiv.org/content/10.1...). Full process—from lysis to grid prep—in just 3 hours. Look how pretty it is (even if a bit too diluted)! This is a game-changer🚀.
A new year, a new social network and a new article in @naturecomms.bsky.social ! It unveils how archaeal RPA orchestrates the recruitment of key players in 🧬 replication primase and polD through its WH domain, with structures of both complexes!! rdcu.be/d6GAY
Communication between DNA polymerases and Replication Protein A within the archaeal replisome
Nature Communications - The single stranded DNA binding protein RPA plays a pivotal role in DNA replication. The archaeal RPA hosts a WH domain that interacts with the DNA primase and the...
rdcu.be
We are pleased to share our work on the evolution of translation initiation now published in Nature Communications. Take a look at leaderless mRNAs and eS26 in the small ribosomal subunit of Saccharolobus solfataricus. rdcu.be/d5pgg