CryoCloud v2.34 is out! Highlights include Live Analysis for real-time cryo-EM image processing, an Interactive Masking tool, Ligand Visual Inspector, and MolProbity validation. Find the full release notes here: connect.cryocloud.io/release-note... #cryoEM #structuralbiology

CryoCloud Map of the Month: TRPV3 in lipid nanodisc We reprocessed EMPIAR-10400 using CryoCloud and achieved: 🚀 3.1 Å resolution (vs. 3.3 Å published) ⚡ 7 compute hours total Curious what your data would look like reprocessed with CryoCloud? 📧 hi@cryocloud.io

🌟 Employee Spotlight: Gydo van Zundert Gydo brings a rare blend of scientific depth and product vision to CryoCloud. He leads our R&D team of scientific software developers, driving the development of novel algorithms and next-generation methods for #cryoEM data analysis. #CryoCloud

CryoCloud will be at the @instruct-eric.bsky.social Best Practices in Cryo-EM Workshop in Milan this week. On March 18, we’ll present a flash talk on how #CryoCloud can help #cryoEM facilities manage users, data storage, and scalable compute. Come say hi! 🔗 instruct-eric.org/events/best-...

🚀 CryoCloud v2.23 is live 🔎 More visualisation in results pages: FSC curves and angular distribution plots (see GIF 👇) ⚡ Faster map viewing: cropped & downsampled map variants now load much faster in the UI 📘 connect.cryocloud.io/release-note... #CryoCloud #CryoEM

🚨 CryoCloud Newsletter Alert Over the past few months, we’ve released multiple platform updates, published new technical content, launched our new website, and connected with the structural biology community at SBDD San Diego. 🔗 Full issue: connect.cryocloud.io/newsletter-m... #CryoEM #CryoCloud

We’ve had many new followers recently, so for those who may be new to CryoCloud — here’s a quick overview of how you can try the platform: tinyurl.com/yrb6vwc4 There are two ways to get started: 🔹Free academic account, or 🔹30-day evaluation trial Links are in the comments 👇 #CryoEM #CryoCloud

🚀 CryoCloud Webinar Series Cryo-EM datasets are getting larger, but processing them shouldn’t be harder. Join our April webinars on cryo-EM data processing and automated workflows with CryoCloud. 📅 Apr 16 - Academia 📅 Apr 23 - Industry Live demo + Q&A #CryoEM #CryoCloud

What does single particle analysis on CryoCloud look like? From dataset creation to particle picking and 2D/3D classification, here’s a short walkthrough: cryocloud.io/solution/end... Request a free academic account or a 30-day trial here: app.cryocloud.io/sign-up #CryoEM #CryoCloud

February Map of the Month: Aca2–RNA We reprocessed EMPIAR-11918 and achieved 2.76 Å in 50.5 compute hours. Sub-3 Å at ~40 kDa is a strong example of what modern cryo-EM workflows (and RELION with Blush) can deliver for small targets. 📧 hi@cryocloud.io #CryoEM #CryoCloud

🌟 Employee Spotlight: Thijmen van Buuren Over the past two years, Thijmen has strengthened CryoCloud’s automation workflows, advancing our research infrastructure and scalable data pipelines. As he wraps up his time with us, we thank him for his dedication and impact. All the best, Thijmen! 🚀

🚀 CryoCloud v2.22 is live! What's new: 🧬 cryoDRGN-AI Ab Initio now available (see the GIF👇) ⚡ GPU-accelerated MotionRefine CC (alpha): 2–3× faster polishing 📊 Redesigned project overview 📺 Embedded viewers in multiple jobs 🔗 connect.cryocloud.io/release-note... #CryoEM #cryoDRGN

🚀 We’ve launched a new CryoCloud website! CryoCloud has grown significantly over the past few years – more users, more deployments & ongoing technical development across infrastructure and automation. It was time for a website that reflects that evolution. 🌐 Take a look: www.cryocloud.io #cryoEM

🚨 New blog: Automated cryo-EM analysis of the gastric proton pump We reprocessed EMPIAR-11057 using a fully automated end-to-end workflow: ⚡ 2.6 Å in 43.5 hr (vs 2.8 Å published) ⚡ 2.4 Å after CTF refinement ⚡ Improved ligand density 🔗 Full article: docs.cryocloud.io/blog/ #cryoEM #CryoCloud

🚀 CryoCloud v2.21 is live! This release delivers a major update to the workflows experience in CryoCloud: 🔹 Convert an existing project into a reusable workflow 🔹 Apply workflows mid-project to extend or repeat processing steps 📘 connect.cryocloud.io/release-note... #CryoCloud #CryoEM

January Map of the Month: Gastric Proton Pump – Revaprazan Complex 🤖 2.6 Å map in 43h, fully automated, no user input 💡 All automation features are available to all CryoCloud users Curious how your data would look reprocessed with #CryoCloud? 📧 hi@cryocloud.io #cryoEM #DrugDiscovery

🚀 CryoCloud v2.20 is live! This release introduces advanced job-branch cloning (see ⬇️), contamination-based filtering, and several performance improvements across the platform. 📘 Full release notes → connect.cryocloud.io/release-note... #CryoCloud #CryoEM

🌟 Welcome to the team, Paddy O'Brien! 🇮🇪 We’re thrilled to welcome Paddy as our new Structural Biology Applications AI Intern. Fun fact: Paddy adds another nationality to CryoCloud’s already diverse mix, bringing us to 8 nationalities and counting! 🍀 Welcome aboard, Paddy! 🙌 #CryoCloud #CryoEM

🔎 Before diving into new 2026 data, we’re looking back at the highlights from the last six months. ⚡️From receptors to kinases and fibrils, each dataset was reprocessed in CryoCloud, often within <2 days, and all resolved to high-quality maps between 2.3 and 3.2 Å. #CryoEM

New year, new projects — and often new tools to evaluate. If you’re curious about CryoCloud, there are two simple ways to get started: 🔷 Free academic account 🔷 30-day evaluation trial Links in the comments 👇 #cryoEM #structuralbiology

As 2025 comes to an end, thank you to the CryoCloud community. Every conversation, dataset, and piece of feedback helps us build a better platform for structural biology. From all of us at CryoCloud, wishing you a warm, restful holiday season and a great start to 2026. ✨

CryoCloud Map of the Month (Holiday Edition 🎄): Alpha‑Synuclein Fibril For December’s edition, we reprocessed EMPIAR‑12229 and generated a 2.3 Å map of the in vitro alpha-synuclein fibril using CryoCloud. 🔬 Dataset size: 5,193 movies 🧠 Compute time: 56.5 hours #CryoEM

📢 CryoCloud Newsletter: End-of-Year Edition is out! A huge thank you to our users, collaborators, and the structural biology community for being part of the journey this year 💙 👉 Read it here: connect.cryocloud.io/newsletter-d... #CryoCloud #CryoEM #StructuralBiology #DrugDiscovery

🌟 Employee Spotlight: Boy Persoon As Co-Founder and CPO of #CryoCloud, Boy has been the driving force behind turning our ambitious product vision into a functional, user-first platform. If you’ve ever used our platform and thought “this just works” – Boy probably had something to do with it 🍀

🚀 CryoCloud v2.18 is live! This release includes two new beta features designed to further automate #cryoEM workflows, along with other improvements. What’s new: 🔹 AutoClass2D – automatically select 2D classes using a reference .mrc file 🔹 Workflow Export & Import lnkd.in/eb8ic_TK #CryoCloud

🚨 New blog: GPU-accelerated motion correction Motion correction remains one of the slowest and most costly steps in #cryoEM workflows. So we rebuilt it from scratch. Our new in-house GPU-accelerated CryoCloud Motion Correction is designed for speed, scale and high throughput. lnkd.in/eiJgsYgJ

🔥 Three years ago, the CryoCloud platform went live 🎉 Today, scientists from 25+ countries rely on it every day for analysing their structural biology data – and we couldn’t be prouder of how far things have come. Thank you to all our users, collaborators, and early supporters 💙 #CryoEM

🚀 CryoCloud v2.17 is live! This release introduces Targets – a new way to organise datasets & projects around your molecule of interest. Targets make it easier to browse results, store reference files in one place and launch automated workflows. connect.cryocloud.io/release-note... #CryoEM

November Map of the Month: CDK-activating kinase (CAK), an oncology target bound to the covalent inhibitor THZ1 💊 We reprocessed EMPIAR‑11793 and produced a 2.5 Å map of the ~85 kDa CAK-THZ1 complex using CryoCloud. 🔬 Dataset size: 12,572 movies 🧠 Total compute time: 52 hours #CryoEM #CryoCloud

🚀 CryoCloud v2.16 is live! This release introduces filament support, including filament picking, visualisation, and a new Initial Model job type for helical workflows. Full release notes → connect.cryocloud.io/release-note... #CryoEM #StructuralBiology