Thrilled to share our latest work, just published in Redox Biology! We show that Cdc48 functions as a redox-sensitive thiol switch regulating proteostasis during stationary phase in yeast.

Cdc48 plays a crucial role in redox homeostasis through dynamic reshaping of its interactome during early stationary phase

Most microbial cells on earth predominantly exist in non-proliferating, dormant conditions, such as the stationary state. The stationary phase is a cr…

sciencedirect.com

Sign up now – Registration deadline extended to 31 May!

EMBO@embo.org · last yr.

Learn about how #chemistry and #CellBiology come together in EMBO Workshop "Thiol-based redox switches: From chemistry to #physiology and #pathology" in Sant Feliu de Guixols, Spain, 13–18 September 2025 Deadline: 18 May meetings.embo.org/event/25-thi... #EMBOthiolSwitches #EMBOevents 🧪

The @EMBO workshop #EMBOthiolSwitches is coming up soon, join us in beautiful Sant Feliu de Guíxols, Spain, 13–18 September 2025! We have a fantastic speaker lineup, with a few spots still open for short talks. Abstract deadline extended to 31 May 2025. meetings.embo.org/event/25-thi...

Thiol-based redox switches: From chemistry to physiology and pathology

Redox reactions have been essential for the emergence of life on Earth, and diverse strategies have evolved for responding to various cellular redox species. These mechanisms are still of vital impor…

meetings.embo.org

We're back for 2025! This week we welcome Adam Klosin and Randal Halfmann for the first IDPSeminar of Season 17!

WOW!!! Beautiful new Nature paper from Burkart Lab UCSD reveals how non-ribosomal peptide natural product synthetases work together. They use tetrazine click chemistry to capture these huge protein complexes mid-reaction. 3 different snapshots show different states. www.nature.com/articles/s41...