Dan Liu
@danliu1.bsky.social
Computational biologist | Bioinformatics, virus-host interactions, LLMs 🦠💻
It works as we last tried sequences from an unreleased glycoprotein-host receptor complex, and it predicted a positive interaction score!
Dan Liu@danliu1.bsky.social · last yr.Our PLM-interact is out in Nature Communications! We show that jointly encoding protein pairs using protein language models improves protein–protein interaction prediction performance and enables fine-tuning to predict mutation effects in human PPIs. www.nature.com/articles/s41...
Our PLM-interact is out in Nature Communications! We show that jointly encoding protein pairs using protein language models improves protein–protein interaction prediction performance and enables fine-tuning to predict mutation effects in human PPIs. www.nature.com/articles/s41...
PLM-interact: extending protein language models to predict protein-protein interactions - Nature Communications
Protein structure can be predicted from amino acid sequences with unprecedented accuracy, yet the prediction of protein–protein interactions remains a challenge. Here, authors present a sequence-based...
nature.com