Abstract submission deadline approaching for the 50th EWGCCE! Join us 6–8 July 2026 in Leuven 🇧🇪 to celebrate 50 years of cardiac cellular electrophysiology. Submit your abstract today (or by 2nd March! 😀) Looking forward to seeing you there! #EWGCCE esc365.escardio.org/event/2035

50th EWGCCE Meeting 2026 on ESC 365

Seminar on Cellular Electrophysiology by the WG on Cardiac Cellular Electrophysiology to improve your practice and prepare for your exams.

esc365.escardio.org

Stuck between a ROCK2 and a hard place? New research just out shows selective ROCK2 inhibition reduces microvascular obstruction after myocardial I/R but doesn’t limit infarct size. Highlights distinct roles for ROCK isoforms in #cardioprotection. 🫀 www.sciencedirect.com/science/arti... #CardioSky

Selective ROCK2 inhibition reduces microvascular obstruction but does not reduce myocardial infarction after ischaemia and reperfusion

Myocardial ischaemia/reperfusion (I/R) injury causes infarction, microvascular obstruction (MVO), and haemorrhage. MVO, often driven by vasospasm, lac…

sciencedirect.com

🫀New research demonstrates that high-throughput, label-free optical oxygen measurements can assess adrenergic effects in iPSC-derived #cardiomyocytes Paired with all-optical #electrophysiology, this enables scalable, human-based preclinical testing #CardioSky www.sciencedirect.com/science/arti...

Response of human iPSC-cardiomyocytes to adrenergic drugs assessed by high-throughput pericellular oxygen measurements and computational modeling

Rate- and contractility-modulating drugs, such as adrenergic agonists and antagonists, are widely used in the treatment of cardiovascular conditions. …

sciencedirect.com

The #deadline for our special edition of @jphysiol.bsky.social looking at Crosstalk of cells in the #heart has been extended until March 6th! Feel free to get in touch or check out the call on the website! physoc.onlinelibrary.wiley.com/hub/journal/... @physoc.bsky.social

#CardioSky

JMCC Plus@jmccplus.bsky.social · 8mo ago

💓 New research from Achlaug et al. @technion.bsky.social reveals how cancer-driven cytokine signalling improves cardiac function and reduces fibrosis. Tumour–heart crosstalk with major therapeutic implications www.sciencedirect.com/science/arti... #CardioOncology #Immunology #Fibrosis #Research

Are you working on #cellular #cross-talk in the #heart? Looking for an outlet for your work? Look no further! Molly O Reillyy, Chris 'O Shea and I are editing an edition of @jphysiol.bsky.social Deadline 6th Jan! #CardioSky physoc.onlinelibrary.wiley.com/hub/journal/...

Final Call! 🫀 Boost your cardiac research career! Scientific Exchange Grants from the WG Cellular Cardiac Electrophysiology offer €2,500 for a 1-month stay in a European lab. Great chance to learn new skills + collaborate internationally. Apply by 8 Dec 2025 👉 escardio.org/Research/Res...

Rab10 to the rescue! 🦸‍♂️🫀! New study from Xu et al. in the December issue shows how this tiny protein helps keep harmful heart growth in check. Read more at: www.sciencedirect.com/science/arti... #CardioProtection #Hypertrophy #CardioSky

Rab10 plays a protective role in the development of pathological cardiac hypertrophy

Prolonged cardiac hypertrophy is a main risk factor for heart failure (HF). During cardiac hypertrophy remodelling, there is an increase in protein sy…

sciencedirect.com

🚀 Calling all early-career cellular cardiac #electrophysiology researchers! The @escardio.bsky.social is offering Scientific Exchange Grants for short-term research visits across Europe 🌍. 📅 Deadline: 8 Dec 2025 — don’t miss out! 👉 Learn more & apply: escardio.org/Research/Res... #CardioSky

Scientific Exchange Grants

Your access to the latest cardiovascular news, science, tools and resources.

escardio.org

🧪 Just out: a new #review of Rac1-driven signalling in cardiomyocytes — covering #hypertrophy, #arrhythmia and #redox stress. A must-read for anyone in cardiac research! 💙 #Cardiology #HeartResearch #SignalTransduction #CardioSky www.sciencedirect.com/science/arti...

Cardiomyocyte Rac1 signaling in hypertrophy, arrhythmia, and cardiac stress adaptation

Cardiovascular disease remains the leading cause of mortality globally and is often marked by pathologic cardiac remodeling including hypertrophy and …

sciencedirect.com

On your way to #AHA or just looking for some weekend reading? Check out the latest paper from Warren et al who uncovered region-specific metabolic and signalling changes in the endocardium vs epicardium in a mini-pig model of #HCM 🫀🫀 sciencedirect.com/science/arti... #CardioSky #AnimalModel

Signaling pathway alterations in hearts of a porcine model harboring a β-myosin heavy chain (MYH7-R403Q) gene variant

The disease-causing myosin variant (MYH7-403Q) is linked to hypertrophic cardiomyopathy (HCM). We carried out a research study of signaling pathways i…

sciencedirect.com

New work from Daoud et al. shows that removal of YAP/TAZ from vascular smooth muscle cells triggers inflammation and immune activation- indicating these factors as essential in vascular health.#vascularbiology sciencedirect.com/science/arti... #CardioSky

YAP/TAZ deletion in vascular smooth muscle cells mirrors atherosclerosis-associated transcriptional programs

The transcriptional co-activators YAP (YAP1) and TAZ (WWTR1) are central regulators of vascular smooth muscle cell (VSMC) phenotype and vascular homeo…

sciencedirect.com

We often treat #diabetes and #heart #disease separately — but they’re connected🫀. A recent study from Srinivas, Alluri et al. shows that removing CHOP in β-cells protects against both metabolic dysfunction and cardiac fibrosis in T2D mice. sciencedirect.com/science/arti... #CardioSky #NewPaper

Deletion of CHOP in beta cell protects mice from cardiovascular complications in type 2 diabetes: evidence from a pre-clinical mouse model

Cardiovascular complications are the leading cause of morbidity and mortality in patients with type 2 diabetes (T2D), which is recognized as a major i…

sciencedirect.com

🫀 New in JMCC Plus! Age, sex & vessel region shape vasomotor function in the descending thoracic #aorta — with #endothelial integrity & relaxation declining with age. Want to know more- check out Saemann et al.: sciencedirect.com/science/arti... #CardioSky @jmccardiology.bsky.social

Age, sex, and vessel region affect the vasomotor function and gene expression signature of the aorta in mice

Vascular aging is associated with endothelial dysfunction, changes in vascular elasticity or stiffness, and the prevalence of cardiovascular diseases.…

sciencedirect.com

New work from Nicole S. York and the group of Leigh Anne Swayne at the University of Victoria charts how #H9c2 heart cells change shape, signal, & express genes during differentiation—revealing both their promise & limits as #cardiomyocyte models. #CardioSky sciencedirect.com/science/arti...

Quantification of morphological, functional, and biochemical features of H9c2 rat cardiomyoblast retinoic acid differentiation

Cell culture models enable advancement in our understanding of heart development and heart disease. The H9c2 rat ventricular cardiomyoblast cell line …

sciencedirect.com

Ever wondered how #Calcium channels cluster in #iPSC derived #Cardiomyocytes? New work just published from Schwenzer et al. should put your mind at rest as they investigated just that! Check out the latest paper for more information www.sciencedirect.com/science/arti... #CardioSky

Nanoscale architecture and dynamics of CaV1.3 channel clusters in cardiac myocytes revealed by single channel nanoscopy

The clustering of L-type calcium channels for functional regulation of intracellular calcium signaling remains poorly understood. Here we applied supe…

sciencedirect.com

“Together, we innovate.” 🧬 @escardio.bsky.social is funding collaboration across borders If you’re an #ECR in #cellular #cardiac #electrophysiology, this is your chance to build connections & push your science forward. escardio.org/Research/Res... Deadline- 8 Dec 2025 #CardioSky #BasicScience

Scientific Exchange Grants

Your access to the latest cardiovascular news, science, tools and resources.

escardio.org

Looking for some weekend reading? 📜 New work from from the University of Ottawa Heart Institute, show how metabolic substrates regulate effects of Wnt/β-catenin signaling in #cardiomyocytes, specifically affecting regulation of #Connexin43 sciencedirect.com/science/arti...

Wnt/β-catenin signaling regulates cardiac Cx43 in a metabolic substrate-dependent manner

Both Nav1.5 and Cx43 are critical for the fast electrical impulse conduction in the myocardium and their reductions create the arrhythmogenic substrat…

sciencedirect.com

New paper out in our September issue from Bass-Stringer and colleagues @bakerresearchau.bsky.social looking at PI3K. Exploring a new #genetherapy to improve heart function in mice and sheep. sciencedirect.com/science/arti... #CardioSky

Generation and evaluation of a novel PI3K-targeting gene therapy in the failing mouse heart and healthy sheep heart

Heart failure (HF) remains a clinical challenge with cardiac dysfunction typically progressing even with treatment, and heart transplants only availab…

sciencedirect.com

Less than 24 hours to go before the #EWGCCE meeting kicks off @escardio.bsky.social #HeartHouse in the South of France! Looking forward to a great scientific programme and meeting up with colleagues and friends over the next days! Safe travels all! #CardioSky

Really nice work just out in @jmccplus.bsky.social ! Congrats to the Authors #CardioSky

JMCC Plus@jmccplus.bsky.social · last yr.

Looking for some weekend reading? We recently published some work from Chambers et al. looking at the effect of an #SGLT2i on #mitochondrial function from non-diabetic mice with #Cardiomyopathy Accompanied by a very nice editorial! sciencedirect.com/science/arti...

Title deadline of 2nd June for @escardio.bsky.social WG in #Cardiac Cellular #Electrophysiology meeting next month. Want to hear about the latest work in cellular cardiac electrophysiology-, you know what you need to do! #cardiosky esc365.escardio.org/event/1815

49th EWGCCE Meeting 2025 on ESC 365

Seminar on Cellular Electrophysiology by the WG on Cardiac Cellular Electrophysiology to improve your practice and prepare for your exams.

esc365.escardio.org

Upcoming Abstract Deadline! Interested in attending the Cardiac Cellular Cross Talk meeting in Birmingham in September? Submit your abstract before the 2nd June! Its going to be a good one! physoc.org/events/cross... #CardioSky

Cross-Talk of Cells in the Heart 2025: Novel Mechanisms of Disease and Arrhythmias

Cross-Talk of Cells in the Heart 2025, an exciting two-day meeting at University of Birmingham (UK) to discuss the latest breakthroughs in cardiac arrhythmia and disease research. Join us

physoc.org

Considering a return to study in the life/environmental sciences at Masters/PhD level after time away? Working and wondering if full/part-time study is the next step for your career? Our RePOWER workshop on 13th June in Oxford/online will provide advice and support. iles.web.ox.ac.uk/repower-retu...

RePOWER: Returning to Postgraduate Study in the Life and Environmental Sciences

iles.web.ox.ac.uk

Interested in presenting your latest #CardiacElectrophysiology data but didnt have chance to submit an abstract to this years #EWGCCE? Still time to submit a title and register for this meeting happening in June/July esc365.escardio.org/event/1815 Hopefully see you there! #CardioSky

49th EWGCCE Meeting 2025 on ESC 365

Seminar on Cellular Electrophysiology by the WG on Cardiac Cellular Electrophysiology to improve your practice and prepare for your exams.

esc365.escardio.org

Some really nice work just out in @jmccplus.bsky.social Congrats to the Authors! #CardioSky

JMCC Plus@jmccplus.bsky.social · last yr.

Looking for some weekend reading or on your way to the ISHR meeting in Japan? Check out the recent work from Alican Guran, @k8weeks.bsky.social et al. investigating the role of B56α as a mediator of cardiac responses to β-AR stimulation! sciencedirect.com/science/arti...

Really nice work just out... Interested in neuro-cardio interactions, have a read!

JMCC Plus@jmccplus.bsky.social · last yr.

New Paper Alert! New work just published investigated the differences in the #electrophysiology of the left and right stellate ganglia What repercussions may this have for #Arrhythmia generation? Congrats to the Authors and thanks to the Reviewers! sciencedirect.com/science/arti... #CardioSky

Deadline Extended until the 10th March for submission of abstracts for the WGCCE meeting this year happening in the south of France! Submit your abstract today at esc365.escardio.org/event/1815 This meeting is the perfect place to conduct some great conversations!! #CardioSky

49th EWGCCE Meeting 2025 on ESC 365

Seminar on Cellular Electrophysiology by the WG on Cardiac Cellular Electrophysiology to improve your practice and prepare for your exams.

esc365.escardio.org

This should be a very interesting webinar! Looking forward to seeing you there! #CardioSky

JMCC Plus@jmccplus.bsky.social · last yr.

Exciting news! Join us for another exclusive ISHR-ES webinar: The Beating Edge of Cardiac Metabolism! 🫀💡 📅 Friday, 7th March 2025 | ⏰ 14:00 to15:00 GMT + 1| 💻 Live Online Hear from three leading experts as they dive into cutting-edge research & innovations. 🔗 Register now: https://buff.ly/4aWIbv1

Fantastic news from @jmccplus.bsky.social 🥳🥳 Congrats to all involved.. Im currently hosting a #SpecialIssue on #Remodelling in #HFpEF! 🫀 Feel free to get in touch if you are interested in submitting!

JMCC Plus@jmccplus.bsky.social · 2y ago

We are delighted to share that JMCC Plus is now officially indexed in PubMed Central (PMC)! Well done to all the editorial team, particularly our EiC @davorpavlovic.bsky.social and deputy @gundrylab.bsky.social 🎉