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Davide Cinat

@davidecinat.bsky.social

Postdoctoral researcher at Stanford University (USA) • NWO Rubicon Fellow • Stem cells • Organoids • Molecular biology • Bioinformatics • Immunology 📍California 🇺🇸 🏠 is 🇮🇹🇪🇸

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Davide Cinat@davidecinat.bsky.social · 9mo ago

Extremely excited to see this out in @science.org Signaling! In this study, we explored the molecular differences between #photon and #proton irradiation and uncovered how #salivary gland stem cells respond to the resulting #inflammatory cues. www.science.org/doi/10.1126/...

IFN-I signaling enhances salivary gland stem and progenitor cell activity after irradiation

Regenerative responses in salivary gland organoids after irradiation are mediated by IFN-I signaling.

science.org

Davide Cinat@davidecinat.bsky.social · 9mo ago

If you work with #scRNAseq, #salivary, #thyroid or #mammary gland #organoids, or are interested in #irradiation and #Notch signaling, you might find this exciting! Our latest paper is now available in @embojournal.org! Check it out! Link below ✨ doi.org/10.1038/s443...

Notch signaling is a driver of glandular stem cell activity and regenerative migration after damage | The EMBO Journal

imageimageRegulatory mechanisms governing stem cell quiescence in glandular organs remain ill-defined. Here, multi-omics profiling uncovers novel stem cell-like populations in mouse salivary gland organoids and reveals Notch signaling as a ...

doi.org

The EMBO Journal@embojournal.org · 9mo ago

Notch signaling is a driver of glandular stem cell activity and regenerative migration after damage @davidecinat.bsky.social, Lara Barazzuol, Rob Coppes et al www.embopress.org/doi/full/10....