David Lougheed
@davidlougheed.bsky.social
Bioinformatics software developer at the Canadian Centre for Computational Genomics @ McGill University, Montreal. https://dlougheed.com
I'm a bit disappointed to learn that @biorxivpreprint.bsky.social lacks a policy on clearly hallucinated references in preprints, unlike arXiv (www.nature.com/articles/d41...) – meaning bioRxiv preprints can mis-cite my/others' work with an invented author list & the wrong journal, DOI, and title...
Work from my M.Sc. with @guilbourque.bsky.social is in this month's issue of Genome Research, detailing my short tandem repeat (STR) genotyping tool for long-read data! Article: genome.cshlp.org/content/36/3... STRkit: github.com/davidloughee...
Read-level genotyping of short tandem repeats using long reads and single-nucleotide variation with STRkit
An international, peer-reviewed genome sciences journal featuring outstanding original research that offers novel insights into the biology of all organisms
genome.cshlp.org
Genome Research @genomeresearch.bsky.social · 5mo agoThe new issue of @genomeresearch.bsky.social is now live. Follow the link to new research on chromosome engineering in 8p syndrome, convergent evolution in arid rodents, and more! tinyurl.com/Genome-Res-3...
Long-read sequencing reveals telomere inheritance patterns from human trios https://www.biorxiv.org/content/10.1101/2025.10.07.680721v1
I’m happy to (finally!) share STRkit, a short tandem repeat genotyping tool for long reads that I've developed in @guilbourque.bsky.social's group over the past few years. Here we describe STRkit & demonstrate state-of-the-art performance in some benchmarks – long reads are great for resolving STRs!
bioRxiv Bioinfo@biorxiv-bioinfo.bsky.social · last yr.STRkit: precise, read-level genotyping of short tandem repeats using long reads and single-nucleotide variation https://www.biorxiv.org/content/10.1101/2025.03.25.645269v1