Thanks Misha for the shout-out! It has been a truly mind-opening journey. WHOLISTIC is one step towards whole-organism neuroscience and a true physiological observatory - with extensions on the way! I am continually amazed by what the data reveals - so much remains to be discovered and mined.

Misha Ahrens@mishaahrens.bsky.social · 11mo ago

Preprint - Excited to present WHOLISTIC, which extends the concept of whole-brain functional imaging to the entire body. Pioneering work by incredibly talented Virginia Ruetten @vmsruetten.bsky.social, this platform reveals whole-organism cellular dynamics in vivo. www.biorxiv.org/content/10.1...

Some really cool work we've been doing @oliolabs.bsky.social. New science opens the door to better medicines.

bioRxivpreprint@biorxivpreprint.bsky.social · last yr.

Sex differences in GLP-1 signaling across species https://www.biorxiv.org/content/10.1101/2025.03.17.643822v1

In this week's edition of our healthcare newsletter InnovationRx, @amyfeldman7.bsky.social & I look at: 💉 The Trump Administration's mixed messaging on vaccines. 🩺 Sex differences in side effects of GLP-1 medications 🤖 Using AI to predict epidemics And more! www.forbes.com/sites/innova...

InnovationRx: Trump Administration Sends Mixed Messages On Vaccines

In this week’s edition of InnovationRx, we look at the policy uncertainty around vaccines, sex differences in GLP-1 drug side effects, the challenges of using AI to predict epidemics and more.

forbes.com

Some really cool work we've been doing @oliolabs.bsky.social. New science opens the door to better medicines.

bioRxiv SysBio@biorxiv-sysbio.bsky.social · last yr.

Sex differences in GLP-1 signaling across species https://www.biorxiv.org/content/10.1101/2025.03.17.643822v1

Check out what we're working on at Olio Labs! 70% of patients taking GLP-1's (like Ozempic) are women, but they experience >2x side effect rates than men. What is driving this difference? We combine human EMR data, mouse & rat behavior, and scRNAseq to figure it out:

This guy.

Gurdeep Pandher of the Yukon@gurdeep.ca · last yr.

Imagine a world where nations help instead of trying to occupy each other. We would all be residents of our tiny Earth in this endless universe. There would be no foreigners anymore. Think of the joy and belonging that would spread everywhere. 🌟 (Share stories that help people find commonality)

Congrats to Xuefeng and the authors on a great paper. academic.oup.com/sleep/advanc... Sometimes things do line up between species