🧬 I really enjoyed working with my colleague Samantha on this project. If you have 2 minutes, this is a great introduction to the three targeted HiFi sequencing approaches and how to choose the right workflow for your application. 😊

PacBio@pacbio.bsky.social · 3w ago

Which targeted sequencing approach is right for you? In this short video, Samantha walks through three key PacBio HiFi approaches: amplicon, hybrid capture, and PureTarget. Watch to find the best fit to simplify your strategy: bit.ly/4ffnKMe #PacBio #HiFiSequencing #Genomics

🧬 What I like about PureTarget™ is its end-to-end approach from targeted HiFi sequencing to dedicated analysis tools. It supports analysis of repeat expansions, homologous genes, structural variants, and copy number changes in a single workflow. Check out the overview below 😊

PacBio@pacbio.bsky.social · 2mo ago

Streamlined sequencing deserves streamlined analysis. The #PureTarget workflow brings complex variant types together into a single pipeline, combining PacBio tools to support comprehensive targeted data analysis. 📘 Download the Pre-Clinical Playbook: bit.ly/437tTEM

Happy to present poster P23.040.D at #ESHG2026 today! 😃 Exploring how #PureTarget and #PacBio HiFi sequencing enable flexible targeting of challenging genomic regions, from repeat expansions to difficult inherited disease genes.

PacBio is live at ESHG 2026! Stop by booth 420 to chat with our team, discuss your sequencing projects, and pick up some exclusive merch while supplies last. Check out our full ESHG agenda to plan your week: bit.ly/3P4WxD4 #ESHG2026 #HumanGenomics #PacBio

Excited to be heading to #ESHG2026 😃 If you're attending, feel free to stop by the #PacBio booth (420) and say hello. I'd be happy to chat about #PureTarget, HiFi sequencing, and targeted sequencing applications. If you're not attending ESHG, you can still catch this webinar on demand below.

PacBio@pacbio.bsky.social · 2mo ago

Repeat expansions and other complex genomic regions continue to challenge traditional sequencing workflows. 🎥 Hear how Dr. Maximilian Thelen is using PureTarget™ HiFi sequencing for repeat expansion analysis and custom panel development. Watch the recording: bit.ly/3S1axP5 #PureTarget

Looking forward to #ESHG next week! 🧬 See you in Gothenburg, and hopefully at the PacBio party too 😉

PacBio@pacbio.bsky.social · 2mo ago

Spots are going fast for the PacBio ESHG 2026 party on Sunday, June 14 at 20:00. 🪩 🇸🇪 Join us at Gothenburg’s historic old shipyard for a fun night of high energy and "Dancing Queen" magic. Capacity is limited, so lock in your registration: bit.ly/49qk9ZI #ESHG #PacBio #ESHG2026

One of my favorite things about PureTarget: simplify complex workflows 😃 Nice short video on carrier screening 🧬

PacBio@pacbio.bsky.social · 2mo ago

Replace legacy assays with one streamlined carrier screening workflow. In this short video, see how PureTarget HiFi sequencing consolidates PCR and Southern blot into a single workflow for challenging genes like FMR1 and SMN. Download our Pre-Clinical Playbook: bit.ly/437tTEM #PureTarget

It’s exciting to see the scale of what’s possible when high-quality genomics and microbiome data meet AI 😃

PacBio@pacbio.bsky.social · 5mo ago

PacBio is proud to partner with Basecamp Research to generate high-fidelity metagenomic data for the Trillion Gene Atlas, a landmark initiative to model biological data at the trillion-gene scale and accelerate AI-designed therapeutics. Learn more here: bit.ly/479RQh3 #PacBio #TrillionGeneAtlas

The 2025 Immuno SMRT Grant is open! Apply for a chance to accelerate your #immunology or #immunotherapy research with PacBio #HiFisequencing through the ProfilAIR immune repertoire profiling assay. Three winners will receive sequencing on two Vega SMRT Cells. Apply here: bit.ly/4pKhgIG #PacBio

Join this #PacBio webinar to see how #HiFiSequencing advances #AntibodyDevelopment with full-length reads, 99.9% accuracy and the throughput for confident clone selection. Learn how it improves phage display workflows. Secure your spot: bit.ly/4oDrUR6

The 2026 #PacBio Genomics Conference Giveaway is LIVE! Travel, registration, and hotel on us. Here’s why showing up matters, straight from Amino Chain’s Jelani Clarke. 👉 Apply here: bit.ly/4oJQxvy #TheresHiFiForThat #PacBio #Conferences

Publication spotlight:Capturing the full picture of genome editing with custom PureTarget panels - PacBio url:https://www.pacb.com/blog/publication-spotlightcapturing-the-full-picture-of-genome-editing-with-custom-puretarget-panels/

A new review calls #PacBio the go-to tech transforming #ALS research. #HiFisequencing uncovers the complex genomic variation short reads miss, giving researchers the full picture and fueling progress toward precision treatments. Read the full study: bit.ly/3JojKx5

Entering the era of precision medicine to treat amyotrophic lateral sclerosis - Molecular Neurodegeneration

With the disease modifying therapy Qalsody (tofersen) which targets the RNA product of the SOD1 gene, having been shown effective in amyotrophic lateral sclerosis (ALS), the present perspective seeks ...

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It’s great to be #ashg 🤩 In case you are here and interested to discuss about HMW DNA extraction from Saliva for #HiFi sequencing pass by my poster 4042 this afternoon from 2.30 to 4.30 pm 😃

The human #microbiome holds enormous potential, but only if we can see it clearly. Join this webinar to learn how #PacBio HiFi sequencing delivers accurate, high-resolution insights with 16S rRNA sequencing and shotgun metagenomics. Secure your spot: bit.ly/4mYmK1G

In case you are interested to know more about PacBio analysis tool for human WGS analysis? My bioinformaticians colleagues did 4 short videos (less than 15 min) easy to follow on variants callings and other tools 😃

PacBio@pacbio.bsky.social · 11mo ago

Unlock the power of #PacBio HiFi whole genome sequencing in our 4-part video series. Learn from PacBio scientists as they walk through tools and examples for variant calling, tandem repeat analysis, paralogous gene resolution, and star (*)-allele calling. Sign up: bit.ly/3HV8Fmh

Too many tabs. Password resets. 47 unread notifications before 9 a.m. Some struggles are inevitable. The ones in your lab? You can fix those with #PacBio. #TheresHiFiForThat launches today with free tools, guides, and a shot at a 2026 genomics conference. 🔗Join in: bit.ly/3JminPa

Curious how long-read sequencing is shaping drug discovery and development? Hear it from the experts. Join panelists from Pfizer, AstraZeneca, GSK, and more as they share how #PacBio HiFi sequencing is transforming the #biopharma industry. Register now: bit.ly/4m3L7KJ

Powered by PacBio: Selected publications from July 2025 - PacBio url:https://www.pacb.com/blog/powered-by-pacbio-selected-publications-from-july-2025/

Folk music fan. Principal Clinical Scientist. Meet David Gokhale – leading the first-ever #Vega install in the UK (and the first in an NHS lab). His take? "It was clear this was a system we were eager to get our hands on.” Soon, you’ll understand why we’re saying #TheresHiFiForThat bit.ly/3IWVuS1

Straight talk from one of the most experienced core lab leads in the game. See why he thinks PacBio long-reads with SPRQ chemistry are the way to go → bit.ly/4lddmpC #PacBio #HiFisequencing #PacBioSPRQ

If you follow where genomics is headed, you’ll want to catch this early. We just wrapped a new interview series with some of the most forward-thinking scientists in the field. Sign up to be one of the first to watch: bit.ly/3FgEtAZ #PacBio #PacBioSPRQ

Explore today’s poster presentations at #ESHG2025 with @deborahmoine.bsky.social — including targeted long-read sequencing of native DNA. 🔍 View full programme: bit.ly/3SScxq4 #HiFiSequencing #Genomics

Great poster presentation #ESHG2025 done by @sarahdoom.bsky.social on @pacbio.bsky.social PureTarget application 😃

Hi from #ESHG2025 day 2 😃 blue sky in Milan and many interesting presentations happening today! If you’re interested using saliva samples for @PacBio sequencing pass by my poster P21.055.A from 13h to 14h 😉

Join ‪@sarahdoom.bsky.social‬ for a preview of our must-see #ESHG2025 activities: expert talks, live #HiFiSequencing demos, tech showcases, and more. Come see what it’s all about! #Genomics

I'm looking forward attending #ESHG2025 in Milan 🇮🇹 I hope to meet many people and discuss about #PacBio HiFi 😃

PacBio@pacbio.bsky.social · last yr.

Join #PacBio at #ESHG2025 to explore scalable solutions for human disease research—from PureTarget panels to Kinnex RNA discoveries. 📍 Join us in Milan, 24–27 May. 📄 View the full agenda: bit.ly/3GG9wX7 The future of sequencing starts with HiFi...

Great first day #PacBioPRISM many interesting presentations and workshops 😃

Are you looking for recommendation to extract HMW DNA? In this blog you'll find 8 tips to get optimal DNA for #PacBio HiFi from divers samples types 🩸 💧 🫀 🐮 🐠 🐞 ☘️ 🧫 - PacBio url:https://www.pacb.com/blog/dna-extraction-tips-and-best-practices-for-hifi-sequencing/

The global #PacBioPRISM tour is coming to San Francisco May 4–6 and Boston May 14–16! Join us for 25+ exciting talks, connect with genomics experts, and explore the latest in sequencing technology.   Register now: bit.ly/43Ruiwp #PacBio