🆕publication in nature communications! Blood #multiomics revealed molecular networks linking lipid mediators, mitochondrial dysfunction and inflammation with progression to #ACLF and short-term mortality. 🔓 www.nature.com/articles/s41... #Hepatology #LiverSky

🎉 DECISION video series complete! 💯 Explore short explainers on #cirrhosis, #ACLF, immune dysfunction, epigenetics, extracellular vesicles, single-cell technologies, and MASH research. 🎥 Full playlist: www.youtube.com/playlist?lis... #LiverDisease #SciComm

What happens before cirrhosis patients suddenly deteriorate? 🪫 Single-cell analysis reveals that monocytes lose energy before organ failure, a signal linked to infections, disease progression, and survival. 🎥 Watch: youtu.be/D1aH-RC6DsM #LiverSky #cirrhosis #liverdisease

Closing out at #EASLCongress! @rautoupe.bsky.social co-chairs a meet-the-expert session on #liquidbiopsy strategies for #liverdiseases Key questions • What works now and which variables matter? • Where's the near-term value? • What mistakes should we avoid? #EASL2026 @hopitalbeaujon.bsky.social

Congrats to Juan Bañares (@vhir.bsky.social) for winning this year's EASL Daniel Alagille Award 🙌 🙌Two-year fellowship 🙌 25k funding Prof. Alagille (1925–2005), French paediatric hepatologist, named the Alagille Syndrome & contributed tremendously to the field. @easlnews.bsky.social #EASLCongress

DECISION member Carlo Alessandria (Università degli Studi di Torino) was part of today's General Session I and contributed a talk on Transjugular intrahepatic portosystemic shunt for refractory hepatic hydrothorax in #cirrhosis: a multicenter European study #EASLCongress #EASL2026 #Hepatology

We are thrilled to congratulate Prof. Paolo Angeli on winning the 2026 EASL Recognition Award. His scientific contributions, leadership, and clinical excellence set a remarkable standard for the field. Congratulations, Prof. Angeli! @unipd.bsky.social @easlnews.bsky.social #EASL2026

📢 Full house at the EF CLIF Networking Session today at #EASLCongress here in their local Barcelona 😎 An exciting new initiative is a new #MasterProgramme, starting in Fall 2026🎓 #cirrhosis #ACLF #LiverFailure #EASL2026 @decision4liver.bsky.social @microb-predict.bsky.social @a-tango.bsky.social

Final session of the day, but an important one nonetheless: Raj Mookerjee (@ucl.ac.uk) presents 'Connected patients (Wearables, implantable sensors, remote follow-up)', during the Postgrad Course: Diagnostics in liver diseases - Shaping the Future #EASL2026 #wearabletech #liverdisease #hepatology

📱 Remote patient monitoring reduced 90-day liver-related hospitalizations in patients with acutely decompensated cirrhosis. #POSTER TOP-469-YI by Alberto Calleri et al. #EASL2026 #DigitalHealth #Cirrhosis

In the co-session 'Patient/provider communication', @korenjak.bsky.social (president of @europeliver.bsky.social) stresses three vital in this communication relationship: ⏳ Time 📍Point-of-view 💬Miscommunication @microb-predict.bsky.social @a-tango.bsky.social #EASL2026 #EASLCongress

🧪 Baseline serum albumin may help identify which patients with cirrhosis benefit most from long-term albumin therapy. #POSTER TOP-455-YI by Enrico Pompili et al. #EASL2026 #Cirrhosis #Hepatology

Full house at the Postgraduate Course: Diagnostics in liver diseases - Advanced chronic liver disease! Joan Genesca (@vhir.bsky.social) co-presents 'From cirrhosis to #cACLD through modern diagnostics' with Prodromos Hytiroglou. cACLD = compensated Advanced Chronic Liver Disease #EASL2026

Continuing our networking programme with Estefania Huergo from @navarrabiomed.bsky.social, who presents about epigenomics on patients with acute decompensated cirrhosis #EASL2026 #epigenomics @easlnews.bsky.social

Next up: @frankuschner.bsky.social ner.bsky.social from @medblab.bsky.social is presenting new DECISION research on #ACLF #decompensation #EASL2026

We're ready to welcome y'all at the DECISION networking session at the cirrhosis & complications track hub at #EASL2026! 🙌 First things first: To set the scene, project coordinator @rautoupe.bsky.social delivers a very brief intro to the DECISION project. #decompensatedcirrhosis #EASL2026

Greetings from the DECISION Investigator Meeting at #EASL2026: Study updates and collaborative discussions with Paolo Caraceni & @rautoupe.bsky.social #ClinicalTrials #cirrhosis

#EASL2026 is right around the corner!✨ Also, join our Networking Session and meet Pierre-Emmanuel Rautou, Estefanía Huergo, and Frank Uschner, who will present some exciting new DECISION research. 📍 Cirrhosis & Complications Track Hub 📆 Wednesday, 27 May 🕜 13:45 - 14:15h See you in Barcelona 🪭!

Why do some cirrhosis patients suddenly deteriorate? #DNAmethylation changes are linked to worse outcomes in acute decompensation, pointing to a key role of #epigenetic regulation in disease progression. 🎥 Watch the explainer: youtu.be/yzTTzx68Sq8 @europeliver.bsky.social

Therapeutic options for MASLD & MASH remain limited. A new standardized rapid animal model reproduces key features of metabolic liver disease within ~8 weeks, supporting faster #preclinical development. 🎥 Watch the video: youtu.be/n-YC_Dpko2A @frankuschner.bsky.social #LiverSky #Hepatology

Acute decompensation of cirrhosis carries high 90-day mortality, but prediction remains challenging. Adding signatures of large #extracellularvesicles may improve scores and prediction. 🎥 youtu.be/24-STOSjLeY #EFCLIF @rautoupe.bsky.social @easlnews.bsky.social @europeliver.bsky.social #LiverSky

In this video, we explore how emergency granulopoiesis, the rapid production of immune cells during crisis, becomes dysregulated in liver failure. 🎥 Watch here: youtu.be/ebN14TCLE24 #LiverSky #LiverFailure #LiverDisease #TranslationalResearch

Emergency Granulopoiesis in Liver Failure: When the Immune System Goes into Chaos

YouTube video by concentris research management

youtu.be

📺New masterclass! ‘Data repositories & their access and publication rights’ covers the history of databases, an overview of repositories used in DECISION & provides a hands-on recipe on how to make the best out of different types of data ⏯️ youtu.be/aoA0WC1yaqs #bioinformatics

Data repositories and their access and publication rights | Masterclass in bioinformatics

YouTube video by concentris research management

youtu.be

DECISION's Year-in-Review2️⃣0️⃣2️⃣5️⃣ 💙Networking session at EASL2025 🩵New publication on maladaptive emergency granulopoiesis 💙Met at Final General Assembly in Bologna 🩵Released 3 high-level lectures We look forward to continuing our collaboration in 2026, finishing strong, and maximizing our impact 💪

New keynote out now! 🌟 Prof. Rubén Francés explains how LSECtin shapes immune tolerance and inflammation in advanced chronic liver disease. Watch here: www.youtube.com/watch?v=pY9H... #LiverSky #cirrhosis #inflammation

The Role of LSECtin in Regulating Inflammation in Advanced Chronic Liver Disease | DECISION Keynote

YouTube video by concentris research management

youtube.com

New DECISION study in @jhepatology.bsky.social: maladaptive emergency granulopoiesis predicts poor outcomes in acutely #decompensatedcirrhosis. This could guide early identification and novel therapies. www.sciencedirect.com/science/arti... #ACLF #LiverSky #Hepatology @easlnews.bsky.social

Maladaptive emergency granulopoiesis predicts poor outcomes in patients hospitalized with decompensated cirrhosis

Whether analysis of whole blood transcriptome assessed on admission of patients with acutely decompensated cirrhosis (ADC) without acute-on-chronic li…

sciencedirect.com

That’s a wrap on our final DECISION GA! From COMBAT & PROSPECT updates to forward-looking discussions and feedback, we’re proud of our shared achievements and motivated to keep advancing ACLF & decompensated cirrhosis research together. #LiverSky

Our final GA is a look back and forward - from major scientific milestones to future discoveries! After a keynote by Prof. Rubén Francés, partners shared results on omics integration, biomarkers & systems medicine - and closed today with a masterclass on data repositories. #cirrhosis

Next week: the final DECISION General Assembly in Madrid! 🎉 Celebrating 5+ years of science, collaboration, & results @rautoupe.bsky.social  @concentris.bsky.social  @navarrabiomed.bsky.social  @bioeticayderecho.bsky.social  @medblab.bsky.social  @europeliver.bsky.social  @easlnews.bsky.social et al

The latest DECISION Masterclass is live! 💡 Clinical Bioinformatics – It’s More Than Pressing a Button with Núria Planell, Cristina Sanchez & David Gomez-Cabrero. Watch here: https://youtu.be/UBm1_JGhw6M #Bioinformatics #ClinicalResearch #ACLF