@david-peede.bsky.social talking about the relation between coalescent times and site patters under an introgressed genetic tree to introduce a new statistic D*. D* is an ILS agnostic test of introgression that performs best under unknown demography.

Defending my PhD this Wednesday at 11am, DM me if you would like to Zoom in!

I am SO THRILLED to share our first fully-lab lab paper!!!!!! Led by @hybridzones.bsky.social & @hagarsoliman.bsky.social, w/ a major assist from @pfschwarz.bsky.social!!!!!!!!!!!!! Read more below, if you're curious (you should be- it's AWESOME!!!!!!!) link: www.sciencedirect.com/science/arti...

Introgression and parental conflict shape repeated occurrences of postzygotic isolation in Mimulus

Postzygotic reproductive isolation is often thought to accumulate as a byproduct of neutral divergence. Yet it frequently evolves rapidly, in line wit…

sciencedirect.com

In a new GBE Review, @david-peede.bsky.social et al. overview the SMC model and extensions, discuss examples of discoveries made with the help of SMC-based inference, and comment on the assumptions, benefits, and drawbacks of various methods. 🔗 doi.org/10.1093/gbe/... #genome #evolution #compbio

Not Just Ne Ne-More: New Applications for SMC from Ecology to Phylogenies

Abstract. Genomes contain the mutational footprint of an organism’s evolutionary history, shaped by diverse forces including ecological factors, selective

doi.org

Delighted that our paper about the distribution of genomic spans of clades/edges in genealogies (ARGs), and using this for detecting inversions and other SVs (and other phenomena that cause local disruption of recombination) is out in MBE academic.oup.com/mbe/article/... (1/n)

The Length of Haplotype Blocks and Signals of Structural Variation in Reconstructed Genealogies

Abstract. Recent breakthroughs have enabled the accurate inference of large-scale genealogies. Through modelling the impact of recombination on the correla

academic.oup.com

Hybridization and introgression are major evolutionary processes. Since the 1940s, the prevailing view has been that they shape plants far more than animals. In our new study (www.science.org/doi/10.1126/... ), we find the opposite: animals exchange genes more, and for longer, than plants

An extraordinary story of archaic introgression🧬: a Denisovan haplotype, introgressed through Neanderthals, selected in the Americas, and linked to an expanded copy number of a tandem repeat. Congrats to @david-peede.bsky.social, Emilia, and the whole team! 👉 Enjoy the read: doi.org/10.1126/scie...

The MUC19 gene: An evolutionary history of recurrent introgression and natural selection

We study the gene MUC19, for which some modern humans carry a Denisovan-like haplotype. MUC19 is a mucin, a glycoprotein that forms gels with various biological functions. We find diagnostic variants ...

science.org

I am so happy to see this fantastic study finally published! Huge congrats to @david-peede.bsky.social , @fervillanea.bsky.social , and all the co-authors. Amazing work! 😍

Fernando Villanea@fervillanea.bsky.social · last yr.

Our paper on the evolution of MUC19 in humans, Neanderthals, and Denisovans is finally out today in Science! This has been a six-year effort by 13 authors to weave together 3 separate but related evolutionary stories around this one gene (more on thread 🧵). www.science.org/doi/10.1126/...

Thrilled to see this paper on MUC19 out. I feel honoured and priviledged to have witnessed this amazing project unfold. Read @fervillanea.bsky.social ’s thread and be prepared for a jaw-dropping story on introgression and selection, and best of all… in Native and Admixed Americans!!

Fernando Villanea@fervillanea.bsky.social · last yr.

Our paper on the evolution of MUC19 in humans, Neanderthals, and Denisovans is finally out today in Science! This has been a six-year effort by 13 authors to weave together 3 separate but related evolutionary stories around this one gene (more on thread 🧵). www.science.org/doi/10.1126/...

Our paper on the evolution of MUC19 in humans, Neanderthals, and Denisovans is finally out today in Science! This has been a six-year effort by 13 authors to weave together 3 separate but related evolutionary stories around this one gene (more on thread 🧵). www.science.org/doi/10.1126/...

The MUC19 gene: An evolutionary history of recurrent introgression and natural selection

We study the gene MUC19, for which some modern humans carry a Denisovan-like haplotype. MUC19 is a mucin, a glycoprotein that forms gels with various biological functions. We find diagnostic variants ...

science.org

@david-peede.bsky.social et al on the convoluted route of a variant of the MUC19 gene: Denisovans (before going extinct) passed the gene to Neanderthals, who (before going extinct) passed it to ancient humans, who then crossed the Bering Strait. Today, 1 in 3 Mexicans carry the genetic variant.

Science X / Phys.org@sciencex.bsky.social · last yr.

A variant of the MUC19 gene, inherited from Denisovans, is more common in people with Indigenous American ancestry and may have supported adaptation to new environments in the Americas.

It’s UNREAL 🤯 what imputation can reveal about archaic Introgression across space 🌎 and time ⏳, and I'm personally STOKED 🤩 to see what the imputation era of archaic introgression will uncover 👀

Marco Capodiferro@marcocapo.bsky.social · last yr.

Turns out imputation of introgressed archaic regions in aDNA works really well — sometimes even better than for the rest of the genome. More on this (and other cool results) in our new preprint 👇 #aDNA #ArchaicIntrogression #imputation doi.org/10.1101/2025...

Congratulations to this year's Hamilton Award finalists! 🎉 Join us Thursday, May 29 to hear these outstanding student talks. See the full schedule on the meeting website: www.evolutionmeetings.org/program-over... @evolmtg.bsky.social