But wait there’s more! Our sister paper “Altered postnatal chromatin development in the NAc primes lifelong stress sensitivity” led by Rebekah Rashford and Lisa Tang (Creed Lab) is ALSO out in #JNeurosci! doi.org/10.1523/JNEUROSCI.2217-25.2026

Altered postnatal chromatin development in the nucleus accumbens primes enduring stress sensitivity

Early-life stress (ELS) sensitizes individuals to subsequent stressors to increase lifetime risk for psychiatric disorders. Within the nucleus accumbens (NAc) — a key limbic and reward-associated brai...

doi.org

Read a summary here @princetonneuro.bsky.social: pni.princeton.edu/news/2026/ea... Including why we think epigenetic priming by ELS isn’t all bad

Early-life stress leaves a lasting mark on the brain

A new study from researchers at Princeton University and Washington University School of Medicine in St. Louis has uncovered a biological mechanism that may explain why early-life adversity can leave ...

pni.princeton.edu

Last but not least, thank you to Jay @hyejaykim.bsky.social for getting it all across the finish line with a beautiful set of knockdown experiments. Showing that Setd7-KD in ELS mice prevents exaggerated dopamine ephys and behavioral response to stress brings it all together (reviewers were right!)

So proud to have “Early-life stress alters H3K4me1 in VTA to prime stress sensitivity” out now in Neuron! This work spanned Many years and Many people contributed. Huge thanks to @hyejaykim.bsky.social, @ja-balouek.bsky.social, Luke Geiger, and Meaghan Creed www.cell.com/neuron/fullt...

Early-life stress alters H3K4me1 in VTA to prime stress sensitivity

Kim, Geiger et al. report that early-life stress increases the chromatin modification H3K4me1 and its enzymatic writer, SETD7, in the ventral tegmental area. They show that this form of epigenetic pri...

cell.com

Excited to share this paper led by two undergrads in the lab, out now in Neurobiology of Stress! Temporal reorganization of maternal care during early life stress in mice doi.org/10.1016/j.yn...

Welcome to the 2026 PNI SYNAPSE Internship Program cohort! 🧠 Edriana 🧠 Nancy 🧠 Letitia 🧠 Andrew 🧠 Bobby Carl 🧠 Emma 🧠 Leo 🧠 Alex 🧠 Julianna 🧠 Charvi Here's to a summer of great science (and plenty of coffee + Bent Spoon ice cream)!

Are you a #neuroscience #Postdoc in #Canada or #Canadian abroad? We are selecting #speakers for the 2025 Canadian Neuroscience Seminars: Postdoctoral Series. Apply by Dec. 2nd @ 23:59 PT. docs.google.com/document/d/1... docs.google.com/forms/d/e/1F... Questions? seminars@can-acn.org