Lee Grimes Lab

@leegrimeslab.bsky.social

🏳️‍🌈Molecular Oncology 🧬Hematology 🩸and Immunology at Cincinnati Children's Hospital. interested in understanding how ancestry affects cancer genetics and clinical outcomes. https://www.cincinnatichildrens.org/research/divisions/i/immunobiology/labs/grimes

ASH Seeks Fundamental Discovery Science Abstracts for #ASH25 IF the quality is there, the fundamental basic science poster and presentations will E X P A N D at ASH25. Its an experiment! Submit your cool basic science before August 5, 2025, at 11:59 p.m.

If you are invited to review abstracts for ASH2026 in a basic science category, please know that I reviewed these sections and pushed for you to do this work. PLEASE HELP ME OUT. We want to increase the quality and representation of basic science at ASH.

New in STM, check out our integrative bulk & single-cell long-read analysis to discover and test new therapies in leukemia. We developed OncoSplice, to define new splicing defined subtypes and predict regulators. PRMT5 inhibition partially rescued mis-splicing & inhibited leukemic growth. More soon!

Splicing regulatory dynamics for precision analysis and treatment of heterogeneous leukemias

Broad dysregulated splicing in AML partially phenocopies splicing factor mutations, is prognostic, and can be pharmacologically reversed.

science.org

"A freeze on meetings of expert panels that peer review grant proposals at the NIH is kicking in this week ... Trump barred NIH from posting new Federal Register notices, which means any study section not advertised before then cannot take place." #medsky 🧪 www.science.org/content/arti...

Trump Tracker: Firings, lawsuits, and U.S. science in chaos

Follow President Donald Trump’s impact on U.S. research and science globally

science.org

The 15th International Workshop on Molecular Aspects of Myeloid Stem Cell Development, will be held at the Jarson-Kaplan Theater of the Aronoff Center for the Arts in Cincinnati, Ohio on May 18-21, 2026. Please hold these dates on your calendar.