After 5.5 years, TTVguideTX has officially come to an end. 🦠💙 The project closes with promising clinical trial results, further analyses underway & publications still to come. Thanks for following! Find the results here: www.ttv-guide.eu/results And here's one final shoutout to T-T-V from the team 🙌

The results of our #TTVguideIT trial were recently presented at the annual meeting of the Upper Austrian Kidney Patients Association. Thanks to Prof. Daniel Cejka at Ordensklinikum Linz for supporting the important dissemination of our findings! Learn more via: www.ttv-guide.eu/results

Torque Teno virus 🦠 is safe to guide immunosuppression in kidney transplantation our manuscript is now available as preprint ☺️ ssrn.com/abstract=740... #TTVguide

Proud that our project was featured by CORDIS Results in Brief - a service of the @ec.europa.eu. #TTVguide

Gregor Bond@gregorbond.bsky.social · 2mo ago

results of our EU funded project ☺️ TTVirus is safe to guide immunosuppression in kidney transplant patients #TTVguide cordis.europa.eu/article/id/4...

#TTV is spreading to #Rheumatology. Congratulations to the @squeezeproject.bsky.social team at @meduniwien.ac.at.

SQUEEZE project@squeezeproject.bsky.social · 3mo ago

🧪 Can tiny amounts of blood help us understand treatment response in #RA? Our latest SQUEEZE study shows that Torque Teno Virus levels can be measured reliably even in small serum samples – an important step towards using large biobanks for future biomarker research. 🔬 www.mdpi.com/2076-3271/14...

Join us Friday 7:15 CEST for best of #ERA2026 @markusathome.bsky.social to learn more about TTV-guided immunosuppression in kidney transplantation #TTVguide youtu.be/OxbYH9yOd6w?...

62nd ERA Congress - Profs. Segelmark, Willcocks, Dixon, Fervenza, Bond, Lambers Heerspink, Neuen

YouTube video by MARKUS at HOMe

youtu.be

Proud and happy to have such a strong partner like @biomerieux.com on board! #TTVguide

bioMérieux@biomerieux.com · 5mo ago

#Kidney Transplants: Torque Teno Virus #biomarker can safely guide a more personalized immunosuppression. The use of bioMérieux’s TTV R-GENE® assay during the TTVGuideTX interventional trial shows how diagnostics can help optimize care for patients at risk. @ttvguidetx.bsky.social #MedSky

First results out! Our study achieved its primary goal: #TTV guided treatment was shown to be as safe as standard care.Check out the @meduniwien.ac.at press release and our website for more information: www.ttv-guide.eu/results

MedUni Wien@meduniwien.ac.at · 5mo ago

Successful trial ✅️ An international team coordinated by #MedUniVienna demonstrated in a #clinicaltrial that #TorqueTenovirus-guided dosing of #immunosuppressants in #kidneytransplant recipients is safe. More about the @ttvguidetx.bsky.social​ study coordinated by @gregorbond.bsky.social​! ⬇️

first data of the TTVguideIT RCT presented by @fredhaupenthal.bsky.social at ERA26 in Glasgow Torque Teno 🦠 virus guided immunosuppression 💊 is safe in kidney TX and might help reducing TAC dose #TTVguide

First data of the TTVguideIT RCT presented @ERA26 in Glasgow 🏴󠁧󠁢󠁳󠁣󠁴󠁿 Personalized Immunosuppression 💊 by Torque Teno 🦠 virus in kidney TX is safe and might help reducing Tacrolimus #TTVguide @fredhaupenthal.bsky.social 👏

the TTVguideTX team @research night for the public @meduniwien.ac.at Vienna - Austria all age groups were welcome to learn about science we presented the principle of TTV-guided immunosuppression #TTVguide

New paper out! Our project partners in Leiden notified an increased risk of BKPyV DNAemia in recipients of deceased donor kidneys when the contralateral kidney recipient develops BKPyV DNAemia www.mdpi.com/2227-9059/14... #ttvguide

New publication: the Vienna group at @meduniwien.ac.at demonstrates the predictive value of #TTV load during months 4 to 12 post-transplant for the incidence of malignancy during years 2 to 5 post-transplant. academic.oup.com/ndt/advance-...

Torque teno virus is predictive for malignancies after kidney transplantation

AbstractBackground and hypothesis. Malignancy, driven by the effects of immunosuppression, is a major complication following kidney transplantation. The wi

academic.oup.com

clinical trial simulations to optimise analysis strategies for multiple endpoints highlight the trade-off between statistical efficiency and interpretability #ttvguide www.nature.com/articles/s41...

If you are a Vienna resident or plan a spring visit to the most liveable city in the World: come join us at our booth at the Researchers Night at @meduniwien.ac.at and learn about the superhero-virus #TTV: langenachtderforschung.at/station/6326

Viren können Superheroes sein oder wie kann man das Immunsystem messen? - #LNF26 Lange Nacht der Forschung

Wir erforschen wie man die Stärke des Immunsystems messen kann. Zuerst erklären wir Ihnen, anhand eines Posters und eines Animationsfilms wie das funktioniert und warum uns das TT Virus dabei hilft. D...

langenachtderforschung.at

The TTVguideIT trial uses a compound endpoint incl infection, organ rejection & patient- & graft survival. The team around @gregorbond.bsky.social at @meduniwien.ac.at used clinical trial simulations to optimise primary-analysis strategies for such multiple endpoints: www.nature.com/articles/s41...

Associations between #TTV and Leukocyte Populations in Solid Organ Transplant Recipients - Partners in The Netherlands provide evidence to support the theory that TTV replicates in immature granulocytes. www.ijidonline.com/article/S120... #TTVguide

Torque Teno Virus Loads and Leukocyte Populations in Stable Outpatient Solid Organ Transplant Recipients

Dosing immunosuppressive medication after solid organ transplantation remains a challenge, with no established marker of immune function available for routine clinical use. Torque teno virus (TTV), a ...

ijidonline.com

Immune Monitoring Goes Viral 🦠 Torque Teno Virus for Immunologic Risk Stratification After Kidney Transplantation ⏩️ new review in TI 🔥 doi.org/10.3389/ti.2... #ttvguide

can viruses 🦠 be superheroes 🦸‍♂️ ? PhD student Felix Herkner just published the statistical analysis plan of the TTVguideIT trial 💪👏 Torque Teno virus guided immunosuppression #TTVguide data cleaning until Q1/26 analysis Q2/26 trialsjournal.biomedcentral.com/articles/10....

Statistical analysis plan for TTVguideIT—a multicentre, patient- and assessor-blinded, non-inferiority, randomised and controlled phase II trial to compare standard and Torque Teno virus-guided immuno...

Background Non-interventional studies indicate an association between Torque Teno Virus (TTV) load in peripheral blood and immunosuppression related outcomes in kidney transplant recipients. This make...

trialsjournal.biomedcentral.com

happy to speak about TT virus 🦠 @Italien 🇮🇹 micro biology congress TTV based immune monotoring #TTVguide

Last week, our team around @gregorbond.bsky.social from @meduniwien.ac.at took part in the "Kinderuni Wien" - Vienna’s Children’s University - to bring science to life for curious kids aged 7 to 12, where the kids learnt that some viruses like TTV can also be superheroes. #TTVguide

Gregor Bond@gregorbond.bsky.social · last yr.

I had great fun at kids university @meduniwien.ac.at today 😁 viruses 🦠 can be superheroes 🦸‍♀️ 🙏 @sebastiankaps.bsky.social and @fredhaupenthal.bsky.social for your support #ttvguide

🗞️ New paper out: Detection of non-intact Torque Teno viral particles. Partners in Italy have analysed the added value of PMAxx™ treatment to detect non-intact Torque Teno viral particles which may overestimate viremia quantified by digital droplet PCR. #TTV #TTVguide www.mdpi.com/1422-0067/26...

Interesting insights into running clinical studies in EU projects.

SQUEEZE project@squeezeproject.bsky.social · last yr.

How to run #clinicaltrials in EU consortia? SQUEEZE expert Daniela Sieghart of @meduniwien.ac.at shares insights into the work of managing clinical studies during the Austrian Research Promotion Agency Coffee Chats on "Health in Action". 🎬 Watch the full talk via www.youtube.com/watch?v=3u6U...

Our team around @gregorbond.bsky.social recently participated at #ESOT2025 - here's our most important learnings: 🔸 More & more groups worldwide pick up the idea of TTV-guided immunosuppression. 🔸 First data on the association between TTV load & the development of malignomes is available. #ttvguide

#ESOTCongress 2025 London 🇬🇧 action at the eposters Torque Teno virus 🦠 for the prediction of Infection post kidney TX first long term data #TTVguide

freddi at #ESOTcongress 🇬🇧 depression is a major factor for reduced HRQOL post kidney TX @fredhaupenthal.bsky.social

happy 😊 meeting you @ #ESOTcongress this Monday 1.7. in London 🇬🇧 talks 🗣️ on Torque Teno virus 🦠 guided immunosuppression 💊 09:30 and 11:00 room S1 13:15 room S5, 16:15 room S4 #ttvguide

meet me at #ESOTcongress in London 🇬🇧 🗓️ July 1, 13:00-14:00, ROOM s5 to discuss Torque Teno virus 🦠 based immunologic monotoring viruses 🦠 can be superheroes 🦸 #ESOT2025 #TTVguide #ESOT

Very happy to see #TTV having the opportunity to be presented and discussed in the realm of #rheumatology Great work of Daniel Mrak and interdisciplinary collaboration😊 POS0914 @squeezeproject.bsky.social #EULAR2025

#TTV spreading to #Rheumatology. Currently happening at #EULAR2025. @pstudenic.bsky.social #TTVguide

SQUEEZE project@squeezeproject.bsky.social · last yr.

Evaluation of the Torque Teno Virus as a potential immunologic marker in #RheumatoidArthritis presented by Daniel Mrak today. Interested in the potential of TTV as an "immunometer"? Follow @ttvguidetx.bsky.social on TTV-guided dosing of immunosuppressive drugs in kidney transplant recipients. #TTV