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(Y|G)iannis P.

@ipatramanis.bsky.social

Postdoctoral Researcher at Globe, University of Copenhagen, Denmark I'm mostly interested in human history and evolution, but also more general: Bioinformatics, Population genetics, Phylogenetics, aDNA, Simulation tools and Palaeoproteomics.

33 Posts247 Follower301 Folgt
Miren Iraeta Orbegozo@mireniraorb.bsky.social · last mo.

Happy to share our new paper on DNA preservation in the Caribbean: Open access: doi.org/10.1098/rsos... 🌎 Summaries in Español, Français, Kreyòl Ayisyen and Kréyòl Gwadloup: shorturl.at/FMHNI 🧵👇 @jazminrm.bsky.social @bitesizedna.bsky.social

Ancient DNA preservation in the Caribbean

Abstract. Ancient DNA (aDNA) analysis has transformed how we study human migration, species dispersals and environmental change, but poor preservation rema

doi.org

Marco Capodiferro@marcocapo.bsky.social · last mo.

Our paper on archaic introgression in imputed ancient genomes is out. Imputation performs better in archaic regions, making Neanderthal and Denisovan segments detectable in low-coverage data. Thousands of archived genomes become usable. doi.org/10.1038/s414...

Archaic ancestry inference in imputed ancient human genomes - Nature Communications

Genotype imputation enables accurate detection of Neanderthal and Denisovan ancestry in low-coverage ancient genomes and allows the identification of introgressed haplotypes as well as candidate genes...

doi.org

Arev P. Sümer@arevsumer.bsky.social · 2mo ago

Our new study with @benmpeter.bsky.social is now on biorxiv! Here we present a new computational tool which makes it possible to conduct population genetic analyses from very contaminated and very low quality archaic human genomes. (1/7)

bioRxivpreprint@biorxivpreprint.bsky.social · 2mo ago

A Method to Analyze Low-Quality Archaic Human Genomes and its Application to the Teshik-Tash 1 Neandertal https://www.biorxiv.org/content/10.64898/2026.08.10.743885v1

Palesa@palaeoprotpalesa.bsky.social · 4mo ago

Hello Hello, If you have some downtime and want to read something excitingly odd, read on the enamel proteins of Homo naledi: www.cell.com/cell/fulltex... Working closely with Alberto, @clairekoenig.bsky.social, @ipatramanis.bsky.social, and the rest of our collaborators was just so wonderful.

Proteomic analysis of dental enamel from 20 Homo naledi individuals shows no male markers

The morphological homogeneity of the middle Pleistocene hominin Homo naledi is reflected in its dental proteome, with no evidence supporting confident identification of male individuals, and the detec...

cell.com

(Y|G)iannis P.@ipatramanis.bsky.social · 5mo ago

Interesting points! If you look at the protein data alone, there are no recovered variants that support these samples being very divergent from modern humans, e.g. 'H.erectus like'. For comparison, the H.antecessor enamel had a variant, placing it as an outgroup to nean, deni, and present day humans

John Hawks@johnhawks.net · 5mo ago

I feel a little heretical in saying that the headlines may say Homo erectus, but the Denisovan connection is pointing me a different direction. The connections over time within China are an old topic, and protein data has made them resurface again. www.johnhawks.net/p/rethinking...

(Y|G)iannis P.@ipatramanis.bsky.social · 7mo ago

The final chapter of my PhD thesis, is finally published in GBE! academic.oup.com/gbe/article/... You can also read the earlier recommendation by PCI in a nice little summary here: evolbiol.peercommunityin.org/articles/rec... #palaeoproteomics #phylogenetics

Assessing the potential of ancient protein sequences in the study of hominid evolution

Abstract. Palaeoproteomic data can provide invaluable insights into hominid evolution over long timescales. Yet, the potential and limitations of ancient p

academic.oup.com

Giulia Zampirolo@giuliazamp93.bsky.social · 8mo ago

Seeing our work on videnskab.dk brings back memories of those fieldwork days. It was a great journey from sampling archaeological and old river sediments in Serbia to the ancient DNA labs in Copenhagen. Read more about the challenges and our findings in the original paper: doi.org/10.1038/s415...

Ancient DNA reconstruction of Late Holocene ecosystems within the Carpathian Basin from paleo-meanders and archaeological deposits - Scientific Reports

The diverse ecology in the Carpathian Basin supported a variety of subsistence strategies throughout the Holocene, ranging from animal husbandry to the management of woodlands, grasslands, and wetland...

doi.org

Mikkel Winther Pedersen@mikkelwp.bsky.social · 8mo ago

It is fascinating how even small traces of DNA preserved in mud can act as an archive of human–environment interactions across millennia. The article is in Danish, apologies for that 🙂 But there are some great ancient DNA details and pictures in there. videnskab.dk/naturvidensk...

Vincent J Lynch 🐘🦣🦥 🦇🐋🐢🐍@devoevomed.bsky.social · last yr.

The slander slanders on. Criticizing #ColossalBio and its co-founder Ben Lamm for their de-extinction #DisInformation campaign complete with #DeepFake dire wolves & woolly mammoths has unleashed a slew poorly written AI news stories about me, again 🙄 www.greenmatters.com/news/lynch-s...

Questioning Credibility: Lynch’s Stem Cell Shortcomings

Vincent Lynch, a researcher at the University at Buffalo, has publicly raised doubts about the value and feasibility of de-extinction efforts.

greenmatters.com

(Y|G)iannis P.@ipatramanis.bsky.social · last yr.

The Paranthropus paper is out! :D See the post from Palesa for a quick summary. Although technically small in scale (4 specimens🦷), this work took many years and many people to complete... Excited to see how the results we show will be applied to future sample sets, now that we know what works!

Palesa@palaeoprotpalesa.bsky.social · last yr.

Hello, Our paper on enamel proteins from Paranthropus robustus has finally been peer reviewed, please have a read here: www.science.org/doi/10.1126/... Paranthropus robustus has been puzzling scientists since its discovery in 1938 in South Africa, where a high number of fossils have been found.

Jorge García@jgarcia-cal.bsky.social · last yr.

I am delighted to share with you some new insights into the selection processes that shaped the Spanish population! This work has been led by @ebosch1972.bsky.social @francesccalafell.bsky.social ( @upf.edu ) in collaboration with Rafael de Cid ( @igtp.bsky.social ) and @sabiagini.bsky.social ⬇️⬇️⬇️

Inferring past demography and genetic adaptation in Spain using the GCAT cohort - Scientific Reports

Scientific Reports - Inferring past demography and genetic adaptation in Spain using the GCAT cohort

nature.com

(Y|G)iannis P.@ipatramanis.bsky.social · last yr.

We’ve released a preprint on #palaeoproteomics and #phylogenetics ! Over the years, I’ve gotten multiple questions on the usefulness of ancient proteins in resolving phylogenetic questions. This is our attempt to provide some answers: www.biorxiv.org/content/10.1...

Assessing the potential of ancient protein sequences in the study of hominid evolution

Palaeoproteomic data can provide invaluable insights into hominid evolution over long timescales. Yet, the potential and limitations of ancient protein sequences to resolve evolutionary relations betw...

biorxiv.org

Frido Welker@fridowelker.bsky.social · 2y ago

Incredibly proud that our paper on the #palaeoproteomics analysis of the Penghu mandible, led by @tsutatsuta.bsky.social and in collaboration with Chun-Hsiang Chang, Enrico Cappellini and co, is out now in @science.org! doi.org/10.1126/scie...

A male Denisovan mandible from Pleistocene Taiwan

Denisovans are an extinct hominin group defined by ancient genomes of Middle to Late Pleistocene fossils from southern Siberia. Although genomic evidence suggests their widespread distribution through...

doi.org