My first PhD paper on the spatial characterization of colon organoids is finally out! Thanks to @hausmannannika.bsky.social for spearheading this collaboration with me. Read more about the study in the post by @mannlab.bsky.social.

Mann Lab@mannlab.bsky.social · 11mo ago

Out in @cp-cellsystems.bsky.social‬: Deep Visual Proteomics shows xenotransplantation drives colon #organoids toward in-vivo-like proteomes supporting their use in regenerative medicine; culture tweaks can mimic this shift. With @kimbakjensen.bsky.social. Lead author Frederik Post explains below:

Very happy to share that part of my postdoc work @ucph.bsky.social @kimbakjensen.bsky.social lab is out now in @cp-cellsystems.bsky.social! In close collaboration with @freddyomics.bsky.social @mannlab.bsky.social we show that orthotopically transplanted organoids recapitulate in vivo phenotypes 👇🏼

Mann Lab@mannlab.bsky.social · 11mo ago

Out in @cp-cellsystems.bsky.social‬: Deep Visual Proteomics shows xenotransplantation drives colon #organoids toward in-vivo-like proteomes supporting their use in regenerative medicine; culture tweaks can mimic this shift. With @kimbakjensen.bsky.social. Lead author Frederik Post explains below:

Our paper is out in Nature today! We use Deep Visual Proteomics (DVP) to dissect α1-antitrypsin deficiency (AATD) in human liver at single-cell resolution. Let us take a tour through proteotoxic stress in intact human tissue — one hepatocyte at a time. www.nature.com/articles/s41...

Deep Visual Proteomics maps proteotoxicity in a genetic liver disease - Nature

High-resolution spatial proteomics were used to map molecular events during hepatocyte stress in pseudotime across all fibrosis stages, recapitulating known disease progression markers and revealing e...

nature.com

Out today in Nature Genetics: Using MS-based proteomics, we mapped 1,200+ plasma proteins in 2,100+ children, showing how genetics & development shape blood protein levels during childhood. nature.com/articles/s41588-025-02089-2 #PediatricProteomics #pQTL First author @liliniu.bsky.social explains ⬇️

Plasma proteome variation and its genetic determinants in children and adolescents - Nature Genetics

This mass spectrometry-based proteomic study profiles the plasma proteome in 2,147 children and adolescents and reveals its association with age, sex, puberty, body mass index and genetics.

nature.com