Happy to see @lizthayer.bsky.social's magnum opus published in peer-reviewed form in @cp-cellsystems.bsky.social!! Check it out! www.cell.com/cell-systems...

Single-cell heterogeneity in interferon induction potential is heritable and governed by variation in cell state

Thayer et al. used multiple approaches to uncover why only a few cells in a population express IFN upon RNA stimulation. They found that variation in cell signaling state at the time of stimulation is...

cell.com

Chris Brooke@christopherbrooke.bsky.social · 10mo ago

Check out @lizthayer.bsky.social's new preprint exploring factors that influence cell-to-cell heterogeneity in interferon (IFN) induction potential!

Happy to see @joelrc.bsky.social's paper identifying cellular heterogeneity in basal OASL expression as a major determinant of interferon induction during influenza virus infection out in its final form: www.pnas.org/doi/10.1073/... Happy new year, hope everyone's 2026 is better than 2025!

Check out @lizthayer.bsky.social's new preprint exploring factors that influence cell-to-cell heterogeneity in interferon (IFN) induction potential!

bioRxiv SysBio@biorxiv-sysbio.bsky.social · 10mo ago

Single-cell heterogeneity in interferon induction potential is heritable and governed by variation in cell state https://www.biorxiv.org/content/10.64898/2025.12.09.693293v1

Finally, it's up on bioRxiv! It's been a rewarding journey shaping this story. My deepest gratitude to @vignuzzilab.bsky.social and @christopherbrooke.bsky.social for their incredible support, and to the @mcbillinois.bsky.social & @astar-idlabs.bsky.social for enabling this research

No better reason to join Bluesky then to say the first chapter of my PhD is out as a preprint! New surgeonfish phylogeny, ecomorphological relationships, evolutionary shape correlations-with NEW method to accurately account for phylogenetic covariation among shapes! www.biorxiv.org/content/10.1...

Phylogenetic relationships and the evolution of fin and body shape in the surgeonfishes

Patterns of evolutionary change in the fin and body shapes of fishes are strongly related to dietary ecology and locomotor mechanisms, and associations between shapes affects ecomorphological relation...

biorxiv.org

More than 1800 detainees are missing after the closure of Alligator Alcatraz. Their families and lawyers can’t find them and they’ve vanished from the ICE database. Feels like this should be a much bigger story www.miamiherald.com/news/local/i...

Hundreds of Alligator Alcatraz detainees drop off the grid after leaving site

As of the end of August, the whereabouts of two-thirds of more than 1,800 men detained at Alligator Alcatraz during the month of July could not be determined by the Miami Herald.

miamiherald.com

TreeSort is out at MBE! Fresh off the press so DOI below is not yet working, but you can find the article here: academic.oup.com/mbe/article/... 💡If you want to apply it to your data - please see the tutorial here github.com/flu-crew/Tre...

Revealing Reassortment in Influenza A Viruses with TreeSort

Abstract. Reassortment among influenza A viruses (IAV) facilitates evolution and has been associated with interspecies transmission and pandemics. We intro

academic.oup.com

Molecular Biology and Evolution@molbioevol.bsky.social · last yr.

@alexey-markin.bsky.social @tavisanderson.bsky.social et al. introduce TreeSort, a tool for identifying recent and ancestral reassortment events on datasets with thousands of influenza A virus genomes. 🔗 doi.org/10.1093/molbev/msaf133 #evobio #molbio #virus

Check out @mfarjo.bsky.social's new preprint where she uses a simulation-based approach to explore the evolutionary consequences of genetic mixing through co-infection for segmented viruses: www.biorxiv.org/content/10.1... hope you like it!

The fitness consequences of coinfection and reassortment for segmented viruses depend upon viral genetic structure

Cellular coinfection between multiple virions is a common feature of viral infections. The collective virus-virus interactions enabled by these coinfections can influence the fitness of viral populati...

biorxiv.org

“Department of Homeland Security officers, who are posted outside the woman's Tucson Medical Center hospital room, are refusing to let the new mother speak to a lawyer, as she's requested” tucson.com/news/local/b...

Border agents posted at Tucson maternity ward to quickly deport migrant mom

The Guatemalan woman arrested in the Arizona desert will be given the choice taking her newborn — a US citizen born Wednesday at Tucson Medical Center — with her when

tucson.com

I feel like we need to keep saying this because it’s so insane: This is a legal U.S. resident who has been detained for over a month now for his political opinions.

The New York Times@nytimes.com · last yr.

The Department of Homeland Security denied Mahmoud Khalil permission to attend the birth of his first child, who was delivered at a New York hospital on Monday, according to emails reviewed by The New York Times.

Why can't these viruses be friends? In a new study from her PhD @cvrinfo.bsky.social, #AnnaSims shows that #SARS-CoV-2 infections segregate into distinct microdomains as they spread. But why? (1/N) journals.asm.org/doi/10.1128/...

@joelrc.bsky.social 's paper on differences between the seasonal H1N1 and H3N2 lineages in their relative capacity to antagonize IFN induction and signaling at the single cell level is out now in PLOS Pathogens: journals.plos.org/plospathogen...

Seasonal influenza a virus lineages exhibit divergent abilities to antagonize interferon induction and signaling

Author summary Successful replication and transmission of influenza A viruses (IAVs) requires effective subversion of the innate immune response. We developed a new single cell method to examine the i...

journals.plos.org

Excited to *finally* have @mfarjo.bsky.social 's fantastic paper on SARS-CoV-2 within-host evolutionary dynamics during acute infection published at JVI: journals.asm.org/doi/10.1128/...