Through the integration of the #PEACE autopsy programme, which allows high breadth metastasis sampling, with the #TRACERx lung study, we collected and studied 501 primary and metastatic tumour samples from 24 patients with non-small cell lung cancer (NSCLC) enrolled in the both studies. 2/9

Using MACHINA from @braphael.bsky.social's lab to infer metastatic migration patterns, we found that NSCLC primaries had multiple seeding subclones more often than a single seeding subclone. 4/9

Excited to share our ‘Evolutionary characterization of lung cancer metastasis’ in #TRACERx & #PEACE, published today in @nature.com in collaboration with @charlesswanton.bsky.social @nickymcgranahan.bsky.social @zaccasimo.bsky.social at @ucl.ac.uk & @crick.ac.uk. www.nature.com/articles/s41...

Evolutionary characterization of lung cancer metastasis - Nature

DNA-sequencing data from primary tumours and paired metastases from participants in the TRACERx lung study and PEACE autopsy programme are used to analyse the metastatic diversity of advanced non-smal...

nature.com

🚨 Huge honour to have helped supervise this landmark PEACE study! New insights into metastasis + a unique dataset of unprecedented resolution on metastatic evolution and dissemination that we hope will drive future advances. 🙏 @cancerresearchuk.org @uclhresearch.bsky.social Please take a look 👇

Jamal-Hanjani Lab@jamal-hanjani-lab.bsky.social · 3mo ago

Excited to share our ‘Evolutionary characterization of lung cancer metastasis’ in #TRACERx & #PEACE, published today in @nature.com in collaboration with @charlesswanton.bsky.social @nickymcgranahan.bsky.social @zaccasimo.bsky.social at @ucl.ac.uk & @crick.ac.uk. www.nature.com/articles/s41...

1 in 2 people will get cancer in their lifetime. Our team'll still run @cancerresearchuk.org Muddy Race also this May to highlight the importance of funding cancer research and improving patient outcomes Please support us if you can! #RaceforLife 👉 fundraise.cancerresearchuk.org/team/computa...

Computational Cancer Genomics (CCG) Research Group

We are the Computational Cancer Genomics (CCG) Lab at the UCL Cancer Institute, a group of passionate scientists and clinicians who work on developing computational methods to unravel cancer's mysteri...

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