Modesto Redrejo-Rodriguez

@mredrejo.bsky.social

Left-handed & weekend cyclist. Assoc. Prof. Biochemistry & Bioinformatics @uammadrid.bsky.social and PI @RnR_Lab DNA replication & repair: mechanisms, evolution and biotech 🚲💻🧬🧪 https://linktr.ee/mredrejo

With @remyfurrer.bsky.social, a new piece in Nature Human Behavior. The standard description of a polygenic score as a "genetic predisposition" essentializes a statistical construct. It's not language policing: PGS are a new kind of entity; now is the time to think carefully about what they are.

Polygenic risk scores are not genetic predispositions - Nature Human Behaviour

Nature Human Behaviour - Polygenic risk scores are not genetic predispositions

nature.com

🧬 ¿Te interesa la biología molecular y la biomedicina? Ya puedes solicitar las becas de la Fundación Margarita Salas para asistir a la Escuela de Biología Molecular “Eladio Viñuela-Margarita Salas”, organizada por nuestros investigadores Luis Blanco y Miguel de Vega.

Becas para la XXV Escuela de Biología Molecular Eladio Viñuela-Margarita Salas 2026 - Fundación Margarita Salas

fundacionmargaritasalas.com

New paper out! ♨️ onlinelibrary.wiley.com/doi/10.1002/... In collaboration with Mario Mencía, Pepe Berenguer, and their team at @cbm-csic-uam.bsky.social , we used Tn-seq to analyze the Thermus genome and found that it strikingly tolerates transposon insertions in essential genes.

Tn‐seq of Thermus thermophilus Genome Reveals Unexpected Tolerance to Insertions in Bacterial Common Essential Genes

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onlinelibrary.wiley.com

New paper from the lab from Sriram Garg in my group. We introduce a general substitution matrix for structural phylogenetics. I think this is a big deal, so read on below if you think deep history is important. academic.oup.com/mbe/advance-...

A general substitution matrix for structural phylogenetics.

Abstract. Sequence-based maximum likelihood (ML) phylogenetics is a widely used method for inferring evolutionary relationships, which has illuminated the

academic.oup.com