Genes&Health

@genesandhealth.bsky.social

One of the world’s largest community-based genetics studies, aiming to improve health among Pakistani & Bangladeshi people 🧬 Based at Queen Mary University London.

A major milestone for Genes & Health in Greater Manchester! 🎉 Former Lord Mayor of Manchester, Cllr Yasmine Dar, has become the 3000th local volunteer to join the study, helping shape a healthier future for British South Asian communities.

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Did you know you can explore all this and more via our website? If you're interested in our study and want to keep yourself updated with our newest research studies, understand how to volunteer and learn more about genetics in general, visit lnkd.in/eu2fWx2D Have a question? Visit our FAQ's page!

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Delighted that the 'flagship' manuscript on our @genesandhealth.bsky.social 44k exomes (British Pakistanis & Bangladeshis) is now preprinted. Great academic-industry collaboration. Lots of new associations (mostly additive, a few recessive) and new insights into homoz knockouts & drug discovery.

Georgios (Yiorgos) Kalantzis@yiorkala.bsky.social · last yr.

Preprint alert! 🚨 doi.org/10.1101/2025... Our manuscript on Exome sequencing and analysis of 44,028 British South Asians, using @genesandhealth.bsky.social is now available at @medrxivpreprint.bsky.social! We present several great results, and I’m thrilled to highlight the pieces I worked on:

Understanding mental health is a priority our Community Advisory Board has set and this summer, we'll launch new research on mental wellbeing with a focus on anxiety and depression in British Bangladeshi and Pakistani communities, inviting both current and new More information coming soon!

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By combining thousands of genetic signals into one polygenic risk score, we can pinpoint young British South Asians at highest inherited risk of developing Type 2 diabetes—often years before symptoms appear. Our data shows those in the top 10% of genetic risk develop diabetes up to a decade earlier

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10 years ago, we recruited our first volunteer in East London. Since then, 66,000+ British Pakistani & Bangladeshi volunteers across England have joined Genes & Health—powering one of the world’s largest community-based genetic studies. #1 of 10 in our anniversary countdown. #Genesandhealth10

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NEW RESEARCH: Combining genetic + clinical data helps predict gestational diabetes risk in British Pakistani & Bangladeshi women. Study of 10,000+ women shows those with highest genetic risk were 5X more likely to develop GDM, with 1/3 later developing type 2 diabetes. #MaternalHealth

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We were honoured to have the Mayor of Rochdale, Cllr Shakil Ahmed, show support for Genes & Health at a Health & Wellbeing event with BACP. BACP plays a vital role in tackling deprivation & reducing health inequalities in British Bangladeshi, Pakistani & Kashmiri communities. #GenesAndHealth

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