Thrilled to share our paper "A conserved GTPase complex gates exocytosis for defence and parasitism across alveolates" Ciliates are fantastic to understand rhoptry exocytosis, and cryo-ET once again reveals so much🤩 Thanks to all who contributed. @martacova.bsky.social @yiweichang.bsky.social

Nature Microbiology@natmicrobiol.nature.com · 2w ago

Out Now! A conserved GTPase complex gates exocytosis for defence and parasitism across alveolates #MicroSky

Congratulations to Melanie Ohi for this very well-deserved recognition!

@lizkellogg.bsky.social · 10mo ago

As 2026 chair of the Biophysical Society Cryo-EM subgroup, I am thrilled to announce that Dr. Melanie Ohi has been selected as the recipient of the June Almeida Award: an honor recognizing women scientists whose leadership, scholarship, and mentorship have profoundly shaped the field of cryo-EM.

Excited to share our new @science.org paper! Led by postdocs Ruchao Peng and Xin Xu, we used cryo-EM/ET to reveal the influenza ribonucleoprotein complex structure and its strand-sliding mechanism for RNA synthesis, paving the way for new antivirals. www.science.org/doi/10.1126/...

Molecular basis of influenza ribonucleoprotein complex assembly and processive RNA synthesis

Influenza viruses replicate and transcribe their genome in the context of a conserved ribonucleoprotein (RNP) complex. By integrating cryo–electron microscopy single-particle analysis and cryo–electro...

science.org

Thrilled to share our @elife.bsky.social paper "Inflammasomes primarily restrict cytosolic Salmonella replication within human macrophages" by 1st author Dr. @marisaegan.bsky.social (@cambupenn.bsky.social alum, now faculty @swarthmorecollege.bsky.social)! elifesciences.org/articles/90107 🧵(1/n)

Exciting update on the CryoET Data Portal! A new annotation set from Mart Last & team is now live. They’ve doubled available annotations with >1,800 tomograms of Chlamydomonas reinhardtii which now have almost fully dense labels, and all can be visualized in the browser using Neuroglancer.

AI x Bio Discovery@aixbiobot.bsky.social · 2y ago

Scaling data analyses in cellular cryoET using comprehensive segmentation [new] Comprehensive segmentation of cryoET data enables ontology-based voxel ID, used for context-aware particle picking and faster template matching.

Thrilled to share that our work with the Ben Black Lab, led by a co-mentored star MD/PhD student Katie Kixmoeller, now is formally published! We used cryo-ET to study kinetochore features in human mitotic chromosomes. 🧬🔬❄️

🦟🌍 Join us for the 21st edition of #EMBLMalaria as we strengthen partnerships, share insights, and drive innovations to combat malaria's toll and advance global health. 📅 20 – 22 May 2025 📍 EMBL Heidelberg and Virtual 📝 Submit abstract by 25 Feb 👉🏻 s.embl.org/bmp25-01-bl #malaria #epidemiology